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N&PD Moderators: Skorpio
How toxic is Mephedrone?
- Thread starter Giovanni
- Start date
ColtDan
Bluelighter
- Joined
- Jul 27, 2009
- Messages
- 24,876
Mine went down the toilet for sure, fuuuuuck this drug.
My money is on it caused DIDM or a similar auto-immune reaction. drug induced dermatomyositis. DIDM has been triggered by cocaine use before. The effects are scary similar, purple knees that come and go, discolored knuckles and fingertips, etc etc. A lot of drugs trigger it, but it seems to have a genetic predisposition required too. I am going to get blood creatine tests to determine if this is ruled out, or a possibility. Elevated creatine levels in blood are a strong indicator of DM, although low levels don't rule it out they make the chances of it much lower.
Thankfully even if it is DIDM, the prognosis of this is significantly better than regular DM, and in modern times the prognosis is drastically better than it was only 50 years ago. in the 60's more than half of people with DM died with in 5 years, in a study concluded in 2004 slightly over 90% of people who had been diagnosied with DM ten years previously, in cases where it was not caused by cancer, were still alive, and 15-20% had it go into full remission with treatment. DIDM has significantly higher remission rates, with over 20% having remission with in two years after discontinutation of the drug that triggered it. Although it should be noted that many people with DIDM didn't have the symptoms show up until ~6 months after starting the drug that triggered it. DIDM is very rare, mostly caused by lipid drugs, with reports of it being caused by cocaine, NSAIDs, heavy alcohol use and anti-retroviral drugs as well. Hopefully this isn't what is happening but the more I read about it the more similar the effects caused seem and the more likely I think this is happening.
I have been researching the fuck out of this disorder recently. Not very much information on it, and a lot of contradictory information as a great deal of progress has been made in treating and understanding the disease in just the past ten years, so older articles tend to say things almost completely different from newer ones, especially regarding prognosis.Last edited:
But from what I can tell through google there wasn't an overwhelming amount of evidence for significant health risks, the incidence of serious adverse reactions seems pretty low. So while mephedrone is surely not good for you, do you guys think it is really so bad that all use should be ruled out? I mean, most people on this board are surely ok with putting themselves at some kind of risk?
So, is it a "I'm going to avoid this because I don't know what it does", a "I'm going to avoid this because I don't fancy the long term adverse effects, like one might say about smoking" or is it a "I'm going to avoid this because I don't want to die"?
I just want to understand the feelings you guys have about mephedrone, without having to learn a load of technical chemistry and pharmacology. I've done it a few times now and despite having some minor concerns I was beginning to feel comfortable with it and have shared it with a few people very close to me. But then I read this thread I got a bit worried and started to get the idea that maybe my planned 2-3 week break should be made indefinite.
dread
Bluelighter
For me, it's "I'm going to avoid this because I don't fancy my knees turning purple and fingers falling off"
Cornishman
Bluelighter
Apparently someone I know did 5g's of this one night & tried to cut their arm off to use as a puppet?!
Needless to say, I really think it fucks with the brain!
Bob Loblaw
Bluelight Crew
I've done loads of the shit, gotten things like chest pain and lingering visuals (i knoe rite), but never even the slightest tinge of blueness or any noticeable effects on the immune system. Just my IME, of course. But lately whenever I look at a popcorned ceiling, it starts to swirl, almost like I'm on a hallucinogen. I used to have slight HPPD-esque visuals like that, but they're much more pronounced. Also, this past week I think I almost went into a sleep deprivation/psychosis state with the help of Meph
. Visuals were subtle, sounds turned into voices and things they weren't, I heard voices from no sound at all, things quit making sense, and reality started to seem like a dream. Got a bit unsettling TBH.
Easier to do if you haven't tried it :/f&/b/ said:
Cornishman
Bluelighter
Raw garlic will go down well with the ladies in night clubs 8). Mind you, will probably be drowned out by the reek of sweaty meph, fags and vodka (the staple diet of the young, male, ill educated meph user
)
meph users have a diet of faggots? why they gotta be homos?
Hahaha!
That made me LOL!
dread
Bluelighter
Eating homos makes you lol?
ColtDan
Bluelighter
- Joined
- Jul 27, 2009
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- 24,876
i smell bullshit. 5gs is a stupid amount to do in a night, even if thats possible
it doesn't fuck with brains that bad
Cornishman
Bluelighter
Lol
No one mentioned eating homos.
They were referring to a staple diet of cigarettes and vodka. (cigarettes being 'fags' here in the U.K).
dread
Bluelighter
How do you british people know the sexual orientation of cigarettes?
Cornishman
Bluelighter
Who knows, that's just what I was told. (Although my mate probably did overexaggerate about the dosage).
Lol.
We just call them straight fags or gay fags.
Shiftpicker
Greenlighter
- Joined
- Aug 27, 2009
- Messages
- 3
I feel like a guinea pig everytime I take a drug
ManRider
Bluelighter
- Joined
- Apr 18, 2008
- Messages
- 78
The cases of purple knees and other similar side effects are very worrisome, but it seems that for every incident like this there are at least 100 incidents of people going on multi-gram binges without dangerous side effects. Could it be more accurate that a small minority of people are vulnerable to such dangerous effects due to whatever factor in their biochemistry while the large majority of people will receive no worse than typical stimulant after effects?
vortex30
Bluelighter
Of course that is the case, at the rate this stuff has been used in Israel, UK and Sweden there would have been some major public safety announcements if a significant minority or majority of users were experiencing this. But we can't be certain about that 'no worse', from what the user is aware of, yes that seems accurate, but there could definitely be things happening that users are unaware of.The future ill effects of these multi gram binges i a complete unknown. Given the short term side effects it's not beyond the realms of possibility that this type of use could turn round and bite people in the ass in the future.
fastandbulbous
Bluelight Crew
Seeing the incidence of distressing side effects in the short term, the possibility of nasty long term effects looks more & more likely. Seems thepeople sayinmg "stop with the doom & gloom about mephedrone" aren't replying in this thread - possibly they don't want to read about the side effects in detail...
my instinct is yellow blue green brown whatever, the principle toxic component is the mephedrone itself or more likely its metabolite.
people are clutching at straws with all this batch discussion and color debate, the drug itself has immediate toxic side effects in some people some of the time, and if it is anything like ephedrine or methcathinone I expect it to be associated with increased incidence of cardiac damage as well as renal problems and aneurisms in anyone who uses it regularly for an extended period of time.
I guess we have to wait and see now.
