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Phenethylamines [Mescaline Subthread] Synthetic / Pure Mescaline - Dosage & Methods of Administration

Allylbenzene said:
With the right otc ALDH inhibitors (see earlier post) and predosed lysine (regular amino acid) then 333mg would likely provide a far more spectacular experience (potentially rivaling 2C-B).
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Perhaps yes, but for my first experience and with a slightly unknown likelihood of increased potency from boofing, I decided to stick with just the Mescaline.

If I do it again I would look into inhibitors, or more likely combine it with LSD.
 
Bicycle Tripper said:
Perhaps yes, but for my first experience and with a slightly unknown likelihood of increased potency from boofing, I decided to stick with just the Mescaline.

If I do it again I would look into inhibitors, or more likely combine it with LSD.
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honestly I would LOVE if you tried it with allylbenzenes ALD inhibitors. He's been spouting it so long like it's fact.
Kinda sick of it and would love a single REAL person that isn't a schill to give feedback on it.
 
Bicycle Tripper said:
Honestly it would be more effort for me to get Pomegranates than it would be to get more Mescaline... could be worth a go, I'll try get a bunch next time I trip
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Peppermint and lemon juice also work so pomegranate isn't necessary. Kash from dmt-nexus always recommended using peppermint and lemon juice when he detailed his experiences with HBWR extracts, and I don't think anyone back then realised why those 2 unsuspecting items were so helpful.

Beside peppermint/lemon, there's also fresh orange juice, salicylate, cloves, mace, ginger, fenugreek seeds and apples (as ALDH inhibitors). Pomegranate extract powder is widely available also.

If you're regularly eating cruciferous vegetables then this (according to my heterodox interpretation) will render mescaline weaker/less effective. This is due to sulforaphane which increases (induces) ALDH; many other inducers exist (eg supplements ALCAR, CoQ10, lipoic acid).
 
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Bicycle Tripper said:
Honestly it would be more effort for me to get Pomegranates than it would be to get more Mescaline... could be worth a go, I'll try get a bunch next time I trip
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jealous! I propose a trade .... jp jp. *Quietly mails you a bunch of pomegranites and hopes*

nah but FR mescaline is the one psychedelic that has managed to slip through my hands. ( I should just do the san pedro thing or w/e ) but after living in NM and knowing peyote buttons are around --- idk ill wait
 
notsmokeymcpot420 said:
after living in NM
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Why eat an endangered species when you live in a place that San Pedro grows great? They've even bred varieties of trichocereous that are more potent the peyote in mescaline content and they grow 10x faster and in more diverse climates...

IMO the only reason one would eat peyote in 2026 is to experience the unique entourage effects of peyote's isoquinoline profile including such alkaloids as anhalamine, isoanhalamine, anhalanine, pellotine and so forth, none of which are known to be psychedelics. I've taken peyote on a number of occasions and I would not call it better or worse than San Pedro. I would just call it rarer.
 
Which one you gotta consume more cacti to get there?

I am not super handy with chems -- sometimes i can figure it out. But hell if I trust me as my chemist lol --- my impression was always less cacti eating with buttons? Am Iwrong
 
notsmokeymcpot420 said:
jealous! I propose a trade .... jp jp. *Quietly mails you a bunch of pomegranites and hopes*

nah but FR mescaline is the one psychedelic that has managed to slip through my hands. ( I should just do the san pedro thing or w/e ) but after living in NM and knowing peyote buttons are around --- idk ill wait
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It evaded me for a long time too and when I saw it available (and had a spare wad of money) I had to try it. It is great stuff, I read it described as "The gentle teacher" which seems apt, only it is probably a bit too gentle for me.
 
Wild peyote is typically more potent than San Pedro. But as Didgital pointed out, there are cultivars of San Pedro more potent than peyote. If you can source those, it is less cactus eating. If you want to forego the plant material entirely, CIELO is not hard to figure out. Please do not take an endangered species for selfish/convenience reasons. There are ethical ways to consume peyote - when cultivated from seed by humans. These are quite expensive. Why? Because peyote grows so damn slow unfortunately. Growing one should give you insight why they shouldn't be poached.
 
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xdrc said:
If you want to forego the plant material entirely, CIELO is not hard to figure out.
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I think if the idea is to mimimise the quantity of cactus material, or maximise the amount of mescaline powder one has, then potentiation methods become quite relevant. Besides the mescaline diet and ALDH inhibitors, there's also scopoletin containing plants traditionally used as admixtures to potentiate peyote visions. Scopoletin is a fascinating coumarin with 5-HT2A and dopaminergic activity.
 
Allylbenzene said:
I think if the idea is to mimimise the quantity of cactus material, or maximise the amount of mescaline powder one has, then potentiation methods become quite relevant. Besides the mescaline diet and ALDH inhibitors, there's also scopoletin containing plants traditionally used as admixtures to potentiate peyote visions. Scopoletin is a fascinating coumarin with 5-HT2A and dopaminergic activity.
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Do you just buy scopoletin from amazon?

how do we trip on it
 
Allylbenzene said:
I think if the idea is to mimimise the quantity of cactus material, or maximise the amount of mescaline powder one has, then potentiation methods become quite relevant. Besides the mescaline diet and ALDH inhibitors, there's also scopoletin containing plants traditionally used as admixtures to potentiate peyote visions. Scopoletin is a fascinating coumarin with 5-HT2A and dopaminergic activity.
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Have you or anyone actually used scopoletin with cactus or are we "factually theorizing" as in using LLMs for "facts".
 
scientificMETHood said:
Have you or anyone actually used scopoletin with cactus or are we "factually theorizing" as in using LLMs for "facts".
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He's trying to get everyone to believe his bs so be can write a book on it and go on a podcast with dennis mckenna.

Please do your research before believing a word that he says.
He likes to claim and speak like it's fact that ALD inhibitors slow down the metabolism of secondary metabolites because he thinks* they are responsible for most of the effects of mescaline. However there have been experimental studies in rodents that show that the specific downstream metabolites (like TMPA, TMPE, and N-acetylmescaline) do not actually reproduce the psychedelic state of mescaline. There is no evidence to support that no matter how hard he believes it.

He probably has a website where he sells stinging nettle extracts or some other scopoletin containing plants.
 
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