Rarest drugs you've done?

[notsmokeymcpot42088]

^Indeed

the term 'research chemical' can be a bit deceptive and covers ALOT of ground from shite that is toxic af and invented truly yesterday to substances that have been well researched for humans and just never put into to practice --- or just not in the us in some cases like etizolam, phenezepam....... Prodrugs to conventional drugs like diazepam (avisafone)

They are all not made equal --- the more that get banned the stranger (less desirable) the variations that are created and sold become as a rule of thumb.

 

[unodelacosa]

the more that get banned the stranger (less desirable) the variations that are created and sold become

I'm not sure how you're defining "strange" in terms of psychoactive materials, and I can't agree with the desirability thing either. For example: 4-AcO-DMT, aka psilacetin, was at one time an interesting, useful, and desirable research chemical. Same goes for 4-PrO-DMT, 4-HO-MET, 4-AcO-MET, and 4-PrO-MET. Also 4-HO-MiPT and its acetoxy and propyloxy analogues. You've also got dissos for days that defy this rule. MXE was an RC at one point. Also 3-MeO-PCP, 3-MeO-PCE, 3-HO-PCP, 3-HO-PCE, O-PCP, O-PCE, and so on a so forth…

I will grant you that MDPV and α-PVP are probably the best pyrovalerones out there and subsequent pyros really sucked ass progressively while extra carbon groups were attached to skirt new drug laws and drug scheduling… It's just not always the case. Lysergamides RCs have mostly all been really rewarding and interesting to check out.

 

[notsmokeymcpot42088]

I dont really mess with dissos -- mxe was an exception.... In that category you may be correct.

Just a general rule I have noticed -- the more things that get banned the further away from the original buzz you desire you end up.

Lysergamides you are correct --- idk why it took so long to go there though. Seems like an lsd prodrug would be move #1 if I am looking to replicate.