https://www.nature.com/articles/s41467-024-51856-y <- Check the supplemental data section for synthetic info. Their initial route to 4-allyl-6-oxa-noribogainalog is absolutely fucking absurd, but it's led to the discovery of what I think may be the smallest molecule to selectively upmodulate the kappa subreceptor. If anybody knows of smaller
please let me know. I am a long time admirer of salvia, but working with salvia and expecting consistency is a formula for disappointment, coming from someone who spent a few years cultivating it. Is your problem with the pursuit of kappa PAMs as therapeutics, or is it with the idea of a corporation working on psychedelics/adjacent hallucinogens? Shulgin's initial work was funded by his position at DOW. Ariadne, DOM, DOET, MDMA, mescaline, LSD, ethocin, MDA, AMT and AET are all also drugs that have been patented before, but that doesn't interfere with getting them into the hands of folks who need them without a cent making its way to the company that held the patent.
ASRI (the Alexander Shulgin Research Institute) has two patents right now, one for 2C-B-5-Isopropoxy and the other for 5-MeO-iPALT. Are you arguing this is also invalid for some poorly articulated reason? I fear I'm wasting my time even responding to this post tbh, the more I reread what you wrote the less sense you make.
You say you can't afford to let this continue, but I can't figure out what it is you think you're going to lose from Gilgamesh developing things like Blixeprodil, Bretisilocin, etc., are you a competing company in the space of FDA-approved hallucinogens? I doubt it, you'd probably be able to write a cohesive comment. I still think it's worth amusing your half-assed opinions despite your apparent stance that telling me to "grow up" is meaningful in any way.
What was delusional in the mention of a pharmaceutical with no history of human use yet being viewed as neat? As far as I'm aware, 4-allyl-6-oxa-noribogainalog has not yet seen human use at least, maybe you're aware of more? If you have legitimate information about Gilgamesh that supports any claims you want to make, I'd love to hear it dude, as a mod on this forum I will specifically support the platforming of any information relevant to harm reduction in the psychedelic space. If you have some, feel free to reach out with it, we'll make sure it gets signalboosted here. So far I've had a couple people tell me they have information like this though, to then show nothing for it.
I hope Fester's found stable housing and employment again, last I heard of him was during Covid. I don't think Fester made imitators of shit personally, I think he catalyzed the intersection of an interest in drugs with people who already had a background in chemistry. Nobody I've ever known to half-assedly cook up meth in the US has ever even known who Fester is though, idk may just be regional bias or something. Every single person had been taught by people before them, usually as an oral tradition associated with organized crime networks, and the information inevitably leaks out into those peoples' relatives and friends. Most people with meaningful chem backgrounds synth themselves lisdexamphetamine instead of N-methylamphetamine from my personal observations, but I really can't tell the two apart experientially when orally dosed.
Where did you encounter a trip report of 4-allyl-6-oxa-noribogainalog? I couldn't find anything, and as far as having read thousands of TRs,
join the club buddy. You're on Bluelight. It's probably a good portion of us here.
Proof is absolutely the relevant thing here, I'd love it if you could provide some to back up a single cohesively formed point, at least. It'd be a start. What is psychedelic exclusion? And what is it that I need to "grow the fuck up and tell the people" about? Idk if this is just lazily written out, you were intoxicated, or this is some sort of cognitive thing going on but every word I write, I find myself more convinced you're wasting peoples' time on purpose.
The sector of industry? I'd love a definition on this one too. You write like a fucking LLM hallucination dude, if a simple comment on a forum induces questions instead of answers at the rate yours does, it might just be flouting Grice's maxims that can pretty easily discern whether opening your mouth/writing a word is useful or not. Assume what you want too, I'd implore you to always be critical of info sources but somehow I doubt you have the capacity to meaningfully authenticate information, and especially to generate a well rounded opinion on uh, idk probably anything but I don't know you dude, just this one timesink of a comment.
I assume this is referring to the tianeptine combinations I was talking about? If so, then damn straight it is dude, tianeptine's a fascinating compound.
