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  • BDD Moderators: Keif’ Richards

How dangerous is medetomidine on its own?

C

curiousexplorer

Greenlighter
Joined
Mar 2, 2026
Messages
3
I know that this drug is being added to other opioids and benzos which makes them more deadly, but how dangerous is medetomidine on its own? Let’s say medetomidine 10mg/kg.
 
i cannot find any Medetomidine xylazine alone users, its 100 percent just a contaminant of dope supply, i know its got the zombie tranq open wound thing as bad look but non injection use? i looked around for rec xylazine users and not seeing any. I'm not going to lie these drugs sound interesting on paper
 
It is an alduterant cutter typically mixed with Fent in my city. Its 100x or more stronger than xylazine, so 10mg/kg would kill you a thousand times over, but when they get the dose right ppl just fall asleep standing up off of a few micrograms. The Xylazine was making their limbs fall off so I guess this is better, but I feel bad for the poor souls chasing the dragon still. The W/D's from the tranq substances are apparently multiple times worse than opioids too.
 
I would like to know who the genius is that came up with the bright idea of even contaminating the fentanyl supply in the first place. Don't they know that it is highly dysphoric and nobody would even enjoy it? I just want an explanation I'm just curious what the justification would be
 
opiatekrzy said:
I would like to know who the genius is that came up with the bright idea of even contaminating the fentanyl supply in the first place. Don't they know that it is highly dysphoric and nobody would even enjoy it? I just want an explanation I'm just curious what the justification would be
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The original concept came from an arms race. On particular US city is self-declared "ground zero", and takes pride in having the strongest dope on the east coast. Heroin and Fent can only go so far, and someone with half of a brain realized that spiking the supply with tranquilizers would potentiate the opioid high at some point. If they had a full brain, they would have realized that their first choice of Tranquilizer was making people W/D 10x worse and form grotesque sores before there was an amputation epidemic that decimated the client base.

I was an IV user who quit dope in about a decade ago and never looked back a few years before this development. Everyone that I knew who kept going got killed off by the Fentanyl before Tranq arrived too. I drove through my old running grounds a few years ago and it was just sad. There was a lot less people and they looked to be in worse shape than I remember, and a weirdly higher % was straight up disabled. I was worried that seeing the old neighborhood would make me want to go back, but it was the opposite and I just felt a tremendous amount of pity for ppl stuck in the current meat grinder. I researched online and learned about the Xylazine era of the Fentanyl epidemic. I had gone about as low as I could imagine in my dope days, but injecting something that you know is going to eat your skin is a straight up horror story.

Switching to a tranquilizer that doesn't eat your skin sounds like it would be better, but the "Heroin" supply is now just Fentanyl and an equally strong and fatal Tranquilizer, both of which can cause you to OD from a single flake too small to see with your naked eye. The only users that remain are the poor souls with a foot in the grave. On the bright side, I don't think Opioids draw in a fraction of the new customers around here. They caused such gross side effects and became so lethal that it has lost all appeal to new users.
 
Looking at the big picture it's pretty sad things ended up like this. I personally feel fentanyl doesn't deserve the respect of even being an opiate/opioid. It's a toxic chemical and it's more dysphoric than euphoric for sure
 
From what I gathered, people that go to the emergency room withdrawing from fentanyl that is laced with that garbage, end up being put under in ICU for the length of the acute withdrawal and they are given some form of medotomidine for withdrawal guess it's really bad on the heart and rhythm
 
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