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Tryptamines The Big & Dandy 4-HO-MiPT Thread - 2nd MiPteration

SuperPsych said:
I agree with 4-HO-MIPT being on par with psilocybin in terms of introspection. They both tend to focus on different things and they go about it differently. 4-HO-MIPT is pretty interesting in the fact that even when the introspection gets a bit intensive, the vibe still remains positive; whereas with psilocybin, deep introspection can take on a darker vibe, until the problem is figured out, then it delivers a huge rush of euphoria. 4-HO-MIPT I also do find to be the most erotic of the 4-substituted tryptamines that I've tried. Have never been fortunate enough to take 4-HO-MIPT with a romantic interest, but I imagine it would be sublime.

4-HO-MIPT is likely my favorite tryptamine that I've tried. Followed by 5-Meo-Mipt. I suppose that I ought to try MIPT. I find miprocin to be a very valuable tool. It's still effective for depression, good for mental work. I get the benefits of mushrooms without the intimidation of taking mushrooms, knowing that they'll be a roller coaster ride and that it won't be easy. Miprocin is always what I turn to when I haven't tripped in months - year(s) due to fear of the psychedelic experience. I always choose 4-HO-MIPT to help remind me that psychedelics aren't so bad. Very, very special substance IMO
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Miprocin is also my favorite tryptamine, with N,N-DiPT being a very close second. Miprocin and sex is also an absolutely absurd and intense combination, on par with 2C-B or LSD for me. I agree with your sentiments here about miprocin being more of an upbeat, mania-inducing, depression-deleting kind of thing whereas psilocin (and its various esters like 4-PrO-DMT, 4-AcO-DMT, 4-PO-DMT (aka psilocybin) all have a more "serious" or "profound" sort of vibe. I've pushed miprocin up to 45mg (I am a dosedemon who can tolerate very high amounts of these things, don't do it just because I did) and while it was as intense as the 16-20g range of Psilocybe cubensis would be, it was still a fantastically healing time. I still hda noticeable visuals from that almost a week out, though.
 
Esperighanto said:
I've pushed miprocin up to 45mg (I am a dosedemon who can tolerate very high amounts of these things, don't do it just because I did) and while it was as intense as the 16-20g range of Psilocybe cubensis would be, it was still a fantastically healing time. I still hda noticeable visuals from that almost a week out, though.
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Wow, that's quite extreme! With me it's the opposite: I'm very sensitive to psychedelics. 10 mg can already feel like "too much" (not emotionally, but rather as if boosting music volume digitally, causing clipping). I don't smoke weed, maybe that's why.
This week alone I've done it in 10, 10, and then 6 mg. Usually I wait longer between trips, but I'm kind of on a "sabbatical" and it felt right. The last "trip" (6 mg) was actually the most profound. I was in a negative mood but did it anyway. The 4-HO-MiPT took me to the (very early childhood) traumas that were causing the negativity, and I just began shaking, but it felt good. And the day after, I went cycling and there was very nice "automatic" integration. So I wouldn't say miprocin isn't "profound". It's truly amazing stuff.

BTW, How do y'all dose it? I dissolve the fumarate salt in PG at 20 mg/mL and use a tiny syringe to measure the volume. This works great, except that a small amount remain undissolved no matter what (unlike my previous batch of 4-HO-MET which dissolved without a trace). I suspect it's excess fumarate or another impurity.
 
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CosmicPancakes said:
Wow, that's quite extreme! With me it's the opposite: I'm very sensitive to psychedelics. 10 mg can already feel like "too much" (not emotionally, but rather as if boosting music volume digitally, causing clipping). I don't smoke weed, maybe that's why.
This week alone I've done it in 10, 10, and then 6 mg. Usually I wait longer between trips, but I'm kind of on a "sabbatical" and it felt right. The last "trip" (6 mg) was actually the most profound. I was in a negative mood but did it anyway. The 4-HO-MiPT took me to the (very early childhood) traumas that were causing the negativity, and I just began shaking, but it felt good. And the day after, I went cycling and there was very nice "automatic" integration. So I wouldn't say miprocin isn't "profound". It's truly amazing stuff.

BTW, How do y'all dose it? I dissolve the fumarate salt in PG at 20 mg/mL and use a tiny syringe to measure the volume. This works great, except that a small amount remain undissolved no matter what (unlike my previous batch of 4-HO-MET which dissolved without a trace). I suspect it's excess fumarate or another impurity.
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4-Substituted tryptamines degrade very rapidly in solution, I'd suggest keeping it out as crystal and weighing it that way if you can.
 
Esperighanto said:
4-Substituted tryptamines degrade very rapidly in solution, I'd suggest keeping it out as crystal and weighing it that way if you can.
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Yes I've heard that, but that's actually not my experience. My 4-HO-MET solution, stored in the freezer, is still as potent as it was 1 year ago, and without discoloration.
Do you know what specifically causes degradation of the substance in solution?
I asked Grok (ChatGPT refuses to answer) and it says oxidation is the main reaction causing degradation. Perhaps an excess of fumaric acid (in my batch) is helping me here, acting as an antioxidant. Also, I really take care to keep the substance and its solution away from light as much as possible: I keep the powder in dark bag in the freezer, the solution goes in a small amber vial in the freezer, and in a dark bag when transporting (for outdoor consumption).
 
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CosmicPancakes said:
Yes I've heard that, but that's actually not my experience. My 4-HO-MET solution, stored in the freezer, is still as potent as it was 1 year ago, and without discoloration.
Do you know what specifically causes degradation of the substance in solution?
I asked Grok (ChatGPT refuses to answer) and it says oxidation is the main reaction causing degradation. Perhaps an excess of fumaric acid (in my batch) is helping me here, acting as an antioxidant. Also, I really take care to keep the substance and its solution away from light as much as possible: I keep the powder in dark bag in the freezer, the solution goes in a small amber vial in the freezer, and in a dark bag when transporting (for outdoor consumption).
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Oxygen is very soluble in water (it's what allows fish to 'breathe'), having everything in solution where the molecules are happily jostling about and rapidly coming into contact with each other speeds up the oxidation reaction enormously.
 
idle_curiosity said:
Oxygen is very soluble in water (it's what allows fish to 'breathe'), having everything in solution where the molecules are happily jostling about and rapidly coming into contact with each other speeds up the oxidation reaction enormously.
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Even then, 1 L of water can carry 8 mg of oxygen, so that's 0,04 mg oxygen in a 5 mL vial (1,25 * 10^-6 mol). Not too much opportunity for oxidation of 20 mg (8,6 * 10^-5 mol, about 69 times more than the oxygen). Keeping it properly sealed, deeply frozen, and away from light, and accepting minor loss every time the vial is opened, seems acceptable and would explain the lack of observed degradation on my side?
 
Esperighanto said:
Miprocin is also my favorite tryptamine, with N,N-DiPT being a very close second. Miprocin and sex is also an absolutely absurd and intense combination, on par with 2C-B or LSD for me. I agree with your sentiments here about miprocin being more of an upbeat, mania-inducing, depression-deleting kind of thing whereas psilocin (and its various esters like 4-PrO-DMT, 4-AcO-DMT, 4-PO-DMT (aka psilocybin) all have a more "serious" or "profound" sort of vibe. I've pushed miprocin up to 45mg (I am a dosedemon who can tolerate very high amounts of these things, don't do it just because I did) and while it was as intense as the 16-20g range of Psilocybe cubensis would be, it was still a fantastically healing time. I still hda noticeable visuals from that almost a week out, though.
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Miprocin is truly amazing stuff, has to probably be my favorite tryptamine as well. Its like the 2C-B of tryptamines for me, albeit a more intense headspace than 2C-B, but in relation to shrooms I used to tell people its somewhat to mushrooms what 2C-B is to acid, for me at least.

Highest I went was 65mg intranasal with a big ass joint and that sent me to hyperspace, it was different from DMT. I instead went through these huge cathedrals/castle structures in a dark void and became what felt like experiencing life as a single cell organism of some mycelium derived species. Doesnt make sense when I try to explain it.
The only worrying part was I seemed to enter a state of full body shakes somewhat mimicking hypothermia, I would kind of black out for a moment and my whole vision was overtaken by a dark silver tessaract that would melt into colors, accompanied by an intense buzzing/electronic noise and a strange noise that I at the time thought was the choir of heaven singing and playing music. Euphoria was out of this world
 
Esperighanto said:
Miprocin is also my favorite tryptamine, with N,N-DiPT being a very close second. Miprocin and sex is also an absolutely absurd and intense combination, on par with 2C-B or LSD for me. I agree with your sentiments here about miprocin being more of an upbeat, mania-inducing, depression-deleting kind of thing whereas psilocin (and its various esters like 4-PrO-DMT, 4-AcO-DMT, 4-PO-DMT (aka psilocybin) all have a more "serious" or "profound" sort of vibe. I've pushed miprocin up to 45mg (I am a dosedemon who can tolerate very high amounts of these things, don't do it just because I did) and while it was as intense as the 16-20g range of Psilocybe cubensis would be, it was still a fantastically healing time. I still hda noticeable visuals from that almost a week out, though.
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That gives me courage to explore higher doses of Miprocin. I always would do between 16-20mg and felt that it was more than strong enough at that dose, though I can't help but be curious.

I did do 23mg of Miprocin during my Michael Jordan (Rare Air) psychedelic marathon where every re-dose of something was 23mg to celebrate the GOAT, but by that time I had consumed at least 6 or 7 different psychedelics (phenethylamines, psychedelic amphetamines, tryptamines, LSD), so by the time I took the 23mg of miprocin, it felt closer to what 15mg typically would for me.

I also must try N,N-DiPT. I've always felt a strong pull towards it and 5-MeO-DiPT since I was 15 or 16. 32 almost, and haven't tried either. Maybe I'll try the Foxy this summer as it always struck me as one that would be stellar for summer nights (but then again, what psychedelics aren't?).
 
TheLightBringer said:
Its also one of the psychedelics to give me the most pareidolia out of any substance, lots of eyes, faces, mouths and animal shapes/faces covering every surface I looked at
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Interesting that you say that as miprocin and psilocybin are the 2 drugs that regularly create that phenomenon in myself


Kinda like when you're on meth and watching porn and edging for 3 or 4 straight days, and then suddenly the popcorn ceilings depict all sorts of pornographic scenes

Sorta
 
CosmicPancakes said:
Even then, 1 L of water can carry 8 mg of oxygen, so that's 0,04 mg oxygen in a 5 mL vial (1,25 * 10^-6 mol). Not too much opportunity for oxidation of 20 mg (8,6 * 10^-5 mol, about 69 times more than the oxygen). Keeping it properly sealed, deeply frozen, and away from light, and accepting minor loss every time the vial is opened, seems acceptable and would explain the lack of observed degradation on my side?
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If it's frozen and sealed, then I'd agree that oxidation would be much, much slower and it should be fine for years, but if it's liquid and open to the air then the dissolved oxygen will be constantly replenished and oxidation will be relatively rapid.

Personally, I chuck in a bit of vitamin C as well as sealing, freezing and keeping in the dark, as it's an effective, cheap and positively healthy antioxidant.
 
wow this substance is great, there is something very subtle about its effects, i can see the resemblance towards those of standard mushrooms.

i think i will try 20mg next time, did 10 and was right at this beautiful edge of my normal perception. making music was super interesting, almost a bit LSD like. Downed another 10mg's with a little gin in the next morning then went home to eat big. I kind of want to know what lies beyond that edge now
 
Camomill said:
wow this substance is great, there is something very subtle about its effects, i can see the resemblance towards those of standard mushrooms.

i think i will try 20mg next time, did 10 and was right at this beautiful edge of my normal perception. making music was super interesting, almost a bit LSD like. Downed another 10mg's with a little gin in the next morning then went home to eat big. I kind of want to know what lies beyond that edge now
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It gets absolutely otherworldly at high doses (50mg+), literally realm-shattering experiences from this one. Been sober for many years now but I can still remember the fantastic insanity that a 4-HO-MiPT peak is…
 
TheLightBringer said:
It gets absolutely otherworldly at high doses (50mg+), literally realm-shattering experiences from this one. Been sober for many years now but I can still remember the fantastic insanity that a 4-HO-MiPT peak is…
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amazing, oh it must be! Although for my sensitivity to drugs 50mg would probably... well i don't know really :D i think 50 mg would probably knock most people out of their socks anyways (in the most silverish shimmering neon-river way hehe)
 
Camomill said:
wow this substance is great, there is something very subtle about its effects, i can see the resemblance towards those of standard mushrooms.

i think i will try 20mg next time, did 10 and was right at this beautiful edge of my normal perception. making music was super interesting, almost a bit LSD like. Downed another 10mg's with a little gin in the next morning then went home to eat big. I kind of want to know what lies beyond that edge now
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It forms exceptionaly little tolerance which is fascinating, 4-subs in general are like that for some reason. Many phenethylamines too, it's quite neat. LSD and NBXX's really can make some killer tolerance, though.

Beware jumping straight from 10-20, I've pushed miprocin up to uh, I want to say ~80mg? 75? I'd need to check my notes but I've pushed it to "I am fully unconscious in a DMT-breakthrough-ish experience" territory, and it's a fantastic drug. Yesterday I took 15mg and imo 10, 15, and 20 milligram doses are all completely different, past that I'd say ~28, ~35, ~45, and ~60 are the next sort of "plateaus" for me, subjectively.
 
Esperighanto said:
It forms exceptionaly little tolerance which is fascinating, 4-subs in general are like that for some reason. Many phenethylamines too, it's quite neat. LSD and NBXX's really can make some killer tolerance, though.

Beware jumping straight from 10-20, I've pushed miprocin up to uh, I want to say ~80mg? 75? I'd need to check my notes but I've pushed it to "I am fully unconscious in a DMT-breakthrough-ish experience" territory, and it's a fantastic drug. Yesterday I took 15mg and imo 10, 15, and 20 milligram doses are all completely different, past that I'd say ~28, ~35, ~45, and ~60 are the next sort of "plateaus" for me, subjectively.
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ah yes thanks for the tip, i don't have a reason to push this in a hurry.
I think I'll actually follow that advice.
 
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