Reindeerspotting is crazy!!! I'd love to watch it again, but I can never find a rip with English subtitles like I did in the past.
I can't believe they actually sit there & inject a whole 8mg pill in one sitting. And yet some how nod out & everything (well they were taking benzos too though).
But it shows what tolerance & individual body chemistry can do. I thought bupenorphine was semi-enjoyable similar to my other favorite opioids.
But once you're dependent on it, you can forget about all that. And even if you lost your dependence, it only takes a time or two of using it again before your tolerance starts going back up.
And because of the ceiling effect, taking more Suboxone really doesn't do anything. Unlike with somethiing like heroin, where you can take it every several hours & take more if you need it to get the effects back.
Yes & no. If you're using low doses & it disappears, you could go up a little bit more & maybe get some of it back. But we're talking microgram range doses.
And because buprenorphine has a ceiling effect, after a certain dosage is built up in your body, taking more generally doesn't do anything.
Anything past 8mg for me really doesn't add much to the experience. And with it's long half-life, if you take it every day even at 2-4mg, it's eventually going to build up to that ceiling effect & taking anything higher won't bring much back. These numbers can vary.
After almost 10 years of daily bupe for me, I'd say I'd still rather be on something like heroin. It has more euphoria, more antidepressant effect, more pain relief, more feelings of "contentedness", where as bupe feels kind of hollow. I feel WAY more sedated on buprenorphine than I do on other opioids. Even with a heavy tolerance to it. And because it's so damn long acting, this sedation sticks around waay too long. I got more stimulation on things like heroin or tramadol. But oddly, in the beginning I got similar stimulation from buprenorphine, it was almost slightly comparable to the a tramadol high where you're stimulated & noddy at the same time, but not quite as pleasant, but did the trick.
But after getting use to it, that stimulated feeling is very elusive & if I do get it, it only lasts for maybe an hour. And it's such a 'natural' feeling for me, that I don't necessarily feel "euphoric" or anything when it does happen. Bupe's "high" is so in the background of your mind with how mild it can be by that point, that It can't even be called a high or anything IMO. It's just a natural burst of feeling mentally & physically stable enough to get things done & not feel like a mopey depressed person. It's too bad that that effect didn't stick for me. Even heroin & tramadol at least retained that "get up & get things done" factor for me after extended periods. But I think bupes partial agonism is also at play here, so it has less of a potential to keep giving a good effect in the long run due to many factors (long half life, partial agonist, ceiling effect, sedative metabolites, etc.. etc..).
