The Neuroscience behind the 5-HT2a receptors.

[MedicinalUser247]

That's good to know. Thanks.

 

[MedicinalUser247]

In that case.. Would designing something as bazaar as this work ? https://ibb.co/gjHCF2d

 

[Deleted member 576750]

That's even more polar than the last one lol

 

[Smyth2]

In that case.. Would designing something as bazaar as this work ? https://ibb.co/gjHCF2d

maybe shifting the hydroxy groups to fluorine could work.

I've seen it work on other molecules:

[1] Grover C. Helsley, Larry Davis, Gordon E. Olsen, US4861889 (1989 to Hoechst-Roussel Pharmaceuticals, Inc.).
[2] Grover C. Helsley, Larry Davis, Gordon E. Olsen, US4914204 & US4954511 (Both 1990 to Aventis Pharmaceuticals Inc).

 

[MedicinalUser247]

How would this drug effect the 5-HT2 receptors ? https://ibb.co/JsTsLy3