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Mental Health Coming off Invega/Xeplion (paliperidone) injections v 8.0

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paliperidonevictim2005 said:
what about the people who never recovered 8-10 years later with full anhedonia and sexual dysfunction from 1 injection?
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I will still repeat the same thing I said. Some people recover more slowly. I don't know why you're trying to continue to argue.

On a serious note though, I find it difficult if not impossible to believe that people almost a decade later show no improvement after 1 injection. The effects they will experience regarding ahedonia and sexual dysfunction, may I reiterate, are common across the board for almost all psychiatric medications, and also some other random medication. I was on meds once where a not uncommon side effect is a permanent erection. Not actually an ideal situation as if it continues over time, the less likely they are able to prevent permanent damage.

ALL substances, whether prescribed, non prescribed, illicit, licit, etc, have side effects. It's just a matter of how tolerable they are.

The reality is, I loathe seroquel XR. And lithium. I absolutely hate them both and would never ever ever use them again. The side effects are awful. I was still pissing 15 times a day 2 years after being put on lithium, and I was on it for 1.5 years. Every day.

There are other people in the world who no doubt swear by either lithium, or seroquel XR. For them, these meds are life saving and life changing. For me, they were intolerable.

The same can be said for all psychiatrists medication. This is perfectly normal. I really disliked abilify - personally. I have a friend who absolutely swears by it.
 
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t_xeplionhell said:
Why do you have to repeat yourself so many times? You speak too much for no reason, like a politician. So annoying...
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If someone or some people make the decision to ask me the exact same question that I have already answered for them multiple times, yes I am going to just repeat myself. There is little point saying what I said another way. The other poster kept asking me 'why does it take some people years to have effects go away?' And my answer to that will always be the same as what I wrote.
Mucky said:
It looks like we lost invegatorture he was a good guy , his name was harry … rip harry
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If this user has passed away, we can discuss making a shrine post for him. I will contact other staff.
 
t_xeplionhell said:
Mechanism of Seroquel is completely different, it antagonizes only D1 dopamine receptor type while paliperidone has strong antagonism on D1 to D5, Seroquel is known for its weak antagonism, and it's considered weak AP.
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Seroquel absolutely is not a weak AP even remotely. Maybe for you you had that experience, but I was unable to function at even the most basic of levels. No other medication i have been on at any dose has resulted in me being bedridden for almost a month.

Regardless, even if it were weak (which it's not, seroquel is a highly dangerous medication that as mentioned causes a heightened risk of dementia and alzeimers as well as diabetes from weight gain amongst older people who take it. The pharma industry passing seroquel off as a perfectly safe insomnia medication was one of the most successful tricks they pulled for a while.

Where I live, seroquel has rightfully gone from normal prescription, to being regulated, made a higher level prescription, and only available at reduced cost to individuals with a psychosis history. The fact is, seroquel is primarily abused either to abort stimulant highs, or people apparently go around taking 4 or 5 of them and from what I understand eventually find it impossible to move.

Doesn't seem like a fun time for me, but then again it sort of wasn't ever.

The mechanism of action for APs varies depending on the exact medication. Regardless of that fact, if someone is on a slightly weaker or even really a significantly weaker AP, or multiple med + high dose weaker AP for an extended period of time, logic would stand to reason that the continued exposure to negative side effects from APs all the time will unsurprisingly result in side effects.

Again, I've been on multiple medications, some of which are in fact relatively strong (I have no idea how you can say seroquel is not strong. People treat that shit like quayludes plus I think the developers of seroquel got in big trouble for framing it as an insomnia medication to get more product sales), and in any case, a *starting* dose of 900mg my first medication attempt was not safe, nor was it effective at doing anything but essentially paralysing me. Some of the other meds I used were more or less okay.
 
Is this a correct analysis ?


Half Life = 29-50 days
I’m hoping my half life is around 30-33 days because that is when the severe akathisia started to fade alongside heavy benzo use.



June 1st First Month Loading Dose Injection 234 mg= 12 mg daily oral
daily Severe Akathisia, can barely talk, extremely flat

July 1st 2nd Month 117 = 6 mg daily oral
Moderate Akathesia with daily use of Benzo, severe Anhedonia, can barely talk

August 1st Month 58.5 = 3 mg daily oral
On and off Akathisia, Severe Anhedonia, barely talkInvoluntary Movements of limbs, neck, and jaw, with moderate use of Benzo

September 1st 4th month 29.25 = 1.5mg daily oral
involuntary movements, speech improvement, occasional use of Benzo

October 1st 5th Month 14.6 = .75mg daily oral
daily Involuntary movements, moderate anhedonia, easily fatigued, lowered carb intake toward latter part of month

(153) November 6th Month 7.3 = .375mg daily oral
( planning on starting 4:1 clinical keto diet)




(183) December 7th month 3.6 = .187mg daily oral
(214) January 8th month 1.8 = .09 mg daily oral
(245) February 9th month .9 = .04mg daily oral (LD 14.6=.75)
(274) March 10th month .45 = .02 mg daily oral
(305) April 11th month .225 = .01 mg daily oral (LD 7.3= .375)
(335) May 12th month = .005mg daily oral
(365) June 13th month = .003mg daily oral (LD 3.6 = .187mg)
 
keepinghope said:
Is this a correct analysis ?


Half Life = 29-50 days
I’m hoping my half life is around 30-33 days because that is when the severe akathisia started to fade alongside heavy benzo use.



June 1st First Month Loading Dose Injection 234 mg= 12 mg daily oral
daily Severe Akathisia, can barely talk, extremely flat

July 1st 2nd Month 117 = 6 mg daily oral
Moderate Akathesia with daily use of Benzo, severe Anhedonia, can barely talk

August 1st Month 58.5 = 3 mg daily oral
On and off Akathisia, Severe Anhedonia, barely talkInvoluntary Movements of limbs, neck, and jaw, with moderate use of Benzo

September 1st 4th month 29.25 = 1.5mg daily oral
involuntary movements, speech improvement, occasional use of Benzo

October 1st 5th Month 14.6 = .75mg daily oral
daily Involuntary movements, moderate anhedonia, easily fatigued, lowered carb intake toward latter part of month

(153) November 6th Month 7.3 = .375mg daily oral
( planning on starting 4:1 clinical keto diet)




(183) December 7th month 3.6 = .187mg daily oral
(214) January 8th month 1.8 = .09 mg daily oral
(245) February 9th month .9 = .04mg daily oral (LD 14.6=.75)
(274) March 10th month .45 = .02 mg daily oral
(305) April 11th month .225 = .01 mg daily oral (LD 7.3= .375)
(335) May 12th month = .005mg daily oral
(365) June 13th month = .003mg daily oral (LD 3.6 = .187mg)
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you have to wait until its 0-1 ng/ml and then a few weeks to a few months after that to start healing
 
cmf77 said:
Dude...shut the fuck up.Dont play tough guy.Im serious! I'm informing people so they know when they get treatment any doctor worth a fuck can find something for them to help elevate the pain instead of giving a false diagnosis.
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i deleted my first response to inform you i am done arguing with you stop telling us we won't recover!
 
What is the half-life of INVEGA SUSTENNA? How long does it take for a dose of INVEGA SUSTENNA to be removed from the body?
Be sure that you read, understand, and follow the FDA-approved patient labeling before you use INVEGA SUSTENNA.1 Talk to your healthcare provider or pharmacist if you have any questions.
After receiving an injection of INVEGA SUSTENNA, the release of the drug starts as early as day 1 and lasts as long as 126 days.1
Half-life is defined as the time it takes for 50% of the drug to be removed from the body. After 5 half-lives (calculated by multiplying the half-life value by 5), about 97% of the drug should be removed from the body.
The median (“middle”) apparent half-life of paliperidone, the active ingredient in INVEGA SUSTENNA, following a single-dose administration over the dose range of
39 mg-234 mg ranged from 25 days-49 days.1 The half-life for an individual may not fall exactly within this range. Since these are median values, the half-life may be longer or shorter. The median is the half-way point in the range, so 50% of individuals will have half-lives longer than the median and 50% will have half-lives shorter than the median.
The time it takes for the drug to be fully removed from the body depends on the dose you are taking−the higher the dose, the longer it will take for drug removal. The time also depends on various other factors, including the body’s ability to remove the drug. Since this is a complex answer that depends on many specific patient factors and can vary from one person to another, share any concerns with your healthcare provider or pharmacist.
 
keepinghope said:
What is the half-life of INVEGA SUSTENNA? How long does it take for a dose of INVEGA SUSTENNA to be removed from the body?
Be sure that you read, understand, and follow the FDA-approved patient labeling before you use INVEGA SUSTENNA.1 Talk to your healthcare provider or pharmacist if you have any questions.
After receiving an injection of INVEGA SUSTENNA, the release of the drug starts as early as day 1 and lasts as long as 126 days.1
Half-life is defined as the time it takes for 50% of the drug to be removed from the body. After 5 half-lives (calculated by multiplying the half-life value by 5), about 97% of the drug should be removed from the body.
The median (“middle”) apparent half-life of paliperidone, the active ingredient in INVEGA SUSTENNA, following a single-dose administration over the dose range of
39 mg-234 mg ranged from 25 days-49 days.1 The half-life for an individual may not fall exactly within this range. Since these are median values, the half-life may be longer or shorter. The median is the half-way point in the range, so 50% of individuals will have half-lives longer than the median and 50% will have half-lives shorter than the median.
The time it takes for the drug to be fully removed from the body depends on the dose you are taking−the higher the dose, the longer it will take for drug removal. The time also depends on various other factors, including the body’s ability to remove the drug. Since this is a complex answer that depends on many specific patient factors and can vary from one person to another, share any concerns with your healthcare provider or pharmacist.
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they are bullshit
 
Got my estrogen tested, it's low. Progesterone is also low. I'm going to be pissed if this shit sterilized me.

I'm probably never going to have a baby anyway because I don't feel romantic attraction anymore because of Prozac. Shouldn't have a baby without a partner.
 
InvegaAnon said:
Got my estrogen tested, it's low. Progesterone is also low. I'm going to be pissed if this shit sterilized me.

I'm probably never going to have a baby anyway because I don't feel romantic attraction anymore because of Prozac. Shouldn't have a baby without a partner.
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very unlikely it sterilized you maybe your prolactin is high but im sure you will feel romantic attraction again in a few months its just prozac
 
paliperidonevictim2005 said:
very unlikely it sterilized you maybe your prolactin is high but im sure you will feel romantic attraction again in a few months its just prozac
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I finally had regular periods after getting a proper treatment for my IBD, I had invega, and I haven't had a period since April. I was normal and then it got all fucked up. Luckily it might be fixable, I just hope my insurance covers it. Medicaid is spotty when it comes to repdoductive healthcare stuff.

Prozac can permanently remove sexual and romantic feelings from a person. I don't know if it did that to me, but I just feel a void now. I am truly asexual and aromantic right now.

I got a "message" in the mental hospital right before I got injected, that I should reject the injection because it "will have a cascading effect on my life" would ruin sex and drugs for me (I have PSSD now because I took Prozac because invega made my OCD unmanageable and I can't smoke weed anymore because it makes PSSD worse and it's not as fun as it used to be), make me infertile, and cause multiple organ failure and I would kill myself. I was tempted to go on Lamictal to help my PSSD and it can cause organ failure if you have NAFLD and autoimmune issues. Bullet dodged, remind me to never touch that shit. I've had weird waves of premonition all my life and I didn't listen to that one because I thought I was just being crazy. I got 2/3 here. I'm in a doomed timeline, this wasn't supposed to happen to me.

The "message" also said I would have had a baby if I didn't get invega. I feel like I can't put anything into motion to make that happen now, even if I'm fertile. My life feels like it's been completely leveled. At least I won't take lamictal and kill myself.
 
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Mucky said:
It looks like we lost invegatorture he was a good guy , his name was harry … rip harry
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God damn it, I must be psychic, because I had a bad feeling about what would happen to him. I've had premonitions about death. I reached out to him because of that feeling. Sad to hear this.
 
InvegaAnon said:
God damn it, I must be psychic, because I had a bad feeling about what would happen to him. I've had premonitions about death. I reached out to him because of that feeling. Sad to hear this.
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god has gifted you with a very strong intuition and gut you should have listened to it its so strong for you but its ok we all make mistakes learn from this and never get injected again i have lots of regret too and blame myself because it really is my fault, also rest in paradise harry we love you❤️
 
cmf77 said:
So I just want to throw this out there. I've seen every doctor from harvard,yale,columbia, and cornell and all of them said I was by bi polar and dismissed my MRI's.Low behold a scientist from India found the damage in my brain yesterday.My Hypothalamus, pituatary and pineal glands are all damaged to a high level.Pituatary not so bad but the others are in bad shape.He says he can get me better but not perfect.If he helps me I will gladly pass his name on to all of you.
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Did he say he will help treat the anhedonia? That’s the real game-changer if he can do that… what techniques is he going to use, how long will they take to work? I’m really hopeful from what you’ve said about him
 
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