Man im glad u are ok. Thats insane.
I got quite bad with ketamine a few years back but the bladder irritation got too much. Was like pissing razor blades.. i cant imagine going through that :O
I'm wondering about the RC derivates, both those which are structurally close like O-PCM and these less (O-PCE I had high hopes for given similarity to MXE but either much bunk stuff was going round or it was a failure imho but some like - yet would guess it's none one would get tempted to use daily) or especially 2F-PCM as this was designed to be a K replacement.. is it
only about potency or something specially toxic to either K or certain synthesis routes? To my (still superficial) knowledge John C. Lilly et al didn't get urotoxicity, neither did "the K chemist" mention it.
It certainly felt like K is the absolute worst nightmare about physical toxicity, like the K cramps and all, I only got them once in full strength, this was when doing 25g over like 3 days or so, and it was cristalline but certainly not pure but made to look like it was, which comes to wreckless criminals putting into whatever it needs ... but once I wetted my bed(! never before and never again) from something feeling like an urinary infection from MXE. Yet nothing anywhere near to what K can do - maybe a coincidence as afterwards I was using MUCH more MXE without nothing physical.
How about mental toxicity or personality changes? Never really read about a psychosis from K, but neither anything permanent from MXE but O-PCM certainly can induce some things when abused too much - I was always aiming for the hole but never ever really reached it, had my share of OOB experiences yet always connected with my body which greatly distracted from the trip ... over-dosed / passed out countless times, in acute terms it's perfectly safe but long-term dunno.. would be interesting to read about this in a realistic setting, not some dosed-to-death rats..
Edit: Finally found a vendor for vet grade K (anesket ampoules)

now
only need to convince my gf about it.. Will report about the subjective comparison of effects!
Edit2: Memantine does
something about interactions, can become psychotomimetic but remember having thought that it reduced felt toxicity. Might just be cause of its own analgesic effects and thus lead to worse use but it certainly blocks the after effects of a binge.