I get the visual fuzz after smoking when there's been serotogenic drugs involved. That's the part I enjoy the most. The part that always throws me off is the temporary partial dissociative experience and simultaneous heightening of bodily sensations.
I'll say this though, Shady had a point on the strains. Some light sativas don't tend to be as harsh in terms of peripheral side effects.
I was a little annoyed at how a single puff off a joint hit me the other day on 275 mg pregabalin. I thought the pregab would smooth things out like etizolam does, but it was a fairly uncomfortable and stimulating experience. Opposite of what I expected, but serves me right knowing weed does that to me anyways.
Also, I was pretty amazed at how smashed you can get at hour 6 on low dose pregabalin +0.5 mg etizolam. I was blanking out in the middle of gaming, snapping back into what my eyes were focusing on every so often. Almost in and out of the room with eyes wide open haha. GABA receptor agonists are interesting drugs.
I was looking into some of the mechanisms by which cannabinoids effect the CNS, and I was lead to a few very interesting articles on interneurons and their various roles as selective inhibitors of nerve impulses, while being varied in morphological presentation, type, and general locus in the CNS. It's a whole layer deeper of neuroanatamy and the function of certain types of interneurons and their associated neurochemical and membrane binding affinities, and what changes in chemical environments in the CNS can do in regards to affecting neuroplasticity, such as wiring functional circuits in the brain (also this chemical environment directly effects differentiation of different type of neurons), coding memories, attaching emotions to things like smells or sounds, determination of what stimulus goes where in the brain. It's a rats nest, all things considered, I bet most of us are lucky to still be as functional as we are haha.
I'll find them and link them actually. They're a good read
Cannabinoids have been shown to disrupt memory processes in mammals including humans. Although the CB1 neuronal cannabinoid receptor was identified several years ago, neuronal network mechanisms mediating cannabinoid effects are still controversial in animals, and even more obscure in humans. In...
pubmed.ncbi.nlm.nih.gov
Understanding brain neural circuits begins with understanding their component parts, the cells that form them. GABAergic interneurons, although a minority of cells within the brain, are critical in the control of inhibition. While understanding ...
www.ncbi.nlm.nih.gov
