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How High Are You? V. Dude Where's My Bar?

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Cream Gravy? said:
Dude seriously I hate how much I like bupre. If I dose early enough in the day I can sleep a whole 8 hours that night, which is unprecedented for me these days. It completely turns my mood around when I'm down... I mean, most opioids do, but bupre has the duration and potency on its side.

After a few years of frequent on/off O-DSMT abuse I find I'm pretty tired of the NRI aspect of it. Bupre is still kinda annoying with how it's only a partial agonist... but dem legz!
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Did tramadol for years and I always dug the SNRI properties. The opiate qualities were only pronounced when I smoked hash on top...
 
BK38 said:
Did tramadol for years and I always dug the SNRI properties. The opiate qualities were only pronounced when I smoked hash on top...
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O-DSMT has much more pronounced opioid effects, especially for me, I only need 10-20mg. I mean, the NRI effect is nice sometimes for its anti-depressant properties as well, but it can make me irritable and I'll like snap at my wife for not cleaning something right, you know, petty shit. I blame that reuptake inhibition of norepinephrine, as all opioids can make me a bit grumpy, but especially O-DSMT.
 
Cream Gravy? said:
O-DSMT has much more pronounced opioid effects, especially for me, I only need 10-20mg. I mean, the NRI effect is nice sometimes for its anti-depressant properties as well, but it can make me irritable and I'll like snap at my wife for not cleaning something right, you know, petty shit. I blame that reuptake inhibition of norepinephrine, as all opioids can make me a bit grumpy, but especially O-DSMT.
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I love that desmetramadol man it gets me fuckin going. It does make me kinda an asshole too but in a weird way I enjoy the aggressive extroversion. I use it mostly at work and I really snap my lazy ass coworkers into shape lol they hate me but we get shit done, can't be a coincidence. Fuck you and your tiny tolerance I need at least 150mg lol.

Also you weird people calling it bupre. Bupe damnit!

I need more sleep and drugs...
 
Cream Gravy? said:
O-DSMT has much more pronounced opioid effects, especially for me, I only need 10-20mg. I mean, the NRI effect is nice sometimes for its anti-depressant properties as well, but it can make me irritable and I'll like snap at my wife for not cleaning something right, you know, petty shit. I blame that reuptake inhibition of norepinephrine, as all opioids can make me a bit grumpy, but especially O-DSMT.
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Yeah ,well O-DSMT is a metabolite no? So maybe I was getting the baby nuts of the opiate side of things and some SNRI properties on top. People vary in their metabolization of said substances, I suspect I converted a lot :)
 
BK38 said:
Yeah ,well O-DSMT is a metabolite no? So maybe I was getting the baby nuts of the opiate side of things and some SNRI properties on top. People vary in their metabolization of said substances, I suspect I converted a lot :)
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Yeah, tramadol relies upon its being metabolized into O-DT in order to give its pain killing effects, which is why some people really like it and some don't get anything from it; it requires a certain enzyme in order to metabolize it and some people have more, or less, in their liver.
 
devilsgospel said:
but in a weird way I enjoy the aggressive extroversion. I use it mostly at work and I really snap my lazy ass coworkers into shape lol they hate me but we get shit done, can't be a coincidence.
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I found the periods I abused it most were periods I had a shitty laborious job. I was always a dick to coworkers but for instance, I could put a bunch of pallets up with a forklift in half the time anyone else could, I'd get so amped up and it helped me ignore fatigue from labor. Great drug for working a shit job lol. Made me kinda impulsive though. I think every time I've quit a shitty job it has been while high on O-DSMT. I'd easily get pissed off about bullshit and I'm very blunt even sober so I'd really speak my mind and people don't like that lol
 
Cream Gravy? said:
^^I add the R to Bupe because I have weird obsessions with even shortened words being spelled correctly -_-
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I really feel you on that it also kinda bothered me too, being a grammar nazi and spelling nerd. Bupe just sounds better to me though, that's my writer side coming through and latching onto presentation.

As for desmetramadol (also easier for me to type instead if O-DSMT and an alternative chemical name for it) being a metabolite; I've always metabolized tramadol incredibly well when I used it. I did always like the SNRI property though. I find myself thinking a lot about tapentadol lately and it's serotonin effects being close to a psychedelic. Absolutely baffles me to be able to trip on an opioid. Might grab some...
 
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