OpiateKiller
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Possible to do at home with little chemistry knowledge?
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MDMA &
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What is wrong with the MDMA available today?
- Thread starter Le Junk
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Possible to do at home with little chemistry knowledge?
I mean of course
It depends how diligent and intelligent you are and how quickly you can learn.
Also, you will need to invest in some pure solvents, glassware and fine silica powder. Column chromatography usually uses different mixtures of solvents that are selected experimentally.
There are two types of preparative column chromatography:
1) gravity assisted
2) high pressure
If you choose the latter, you will need more hardware, e.g. a high pressure solvent pump, metal columns, degasser, etc...
Watch this video for an explanation:
Warning:
In USA and Canada's legal system purifying drugs with chromatography is qualified as "manufacturing".
In some tyrannical jurisdictions purchases of glassware and solvents constitute grounds for a search warrant.
Hi,
Just finished reading this thread. Thanks for creating it! I've only tried MDMA a few times (US capsules and pills in Amsterdam), so while it's very, incredibly good every time, I'm just not sure if it was really "magic" or it gets even better. My more experienced friend said it was meh, so that's what brings me here.
@indigoaura : Hi indigoaura. Thanks for all your contributions, sending that powder to EC, reporting the results and so on!
What about trying those Q-Dance presses? They are supposed to be among the best of the Dutch megapills, and several people on this thread said they were magic. QDance presses are also a standard item, unlike powder. So if you, G_Chem, Le Junk, Hilopsilo and others concurred that Q-Dance was the cat's meow, that'd both falsify the initial claim and answer the practical question of most readers here. Right?
If the MAPS trial succeeds, I imagine the final product would be in pill form, like every other medicine. It'd be a pill weighing 240mg and containing 120mg of 99.5% pure MDMA*HCl and 120 mg of inert binder, or something similar.
So working backwards, a question for chemists: is it possible / useful to wash an OG checkpoint or qdance pill in acetone to remove the binder, so you're left with just MDMA*HCl plus synthesis byproducts, basically whatever the lab made and put in the pill. Then use an MDMA purity test from EZ-test to estimate how pure your sample is? Or even send it to EC. Indigo's sample was 80% pure, so how pure is the compound in those qdance pills in comparison?
Edata only tells you that a pill is 250 mg MDMA with a total mass of 500 mg. But that could describe a future MAPS pill with 250mg of 100% pure MDMA and 250 mg of inert binder, which is probably magic. Or 100mg of binder and 400 mg of very impure MDMA*HCl compound, which is likely meh.
If a pill is washed and revealed to have >95% pure MDMA*HCl, and it's STILL not magic, that'd be very interesting and surprising.
Just finished reading this thread. Thanks for creating it! I've only tried MDMA a few times (US capsules and pills in Amsterdam), so while it's very, incredibly good every time, I'm just not sure if it was really "magic" or it gets even better. My more experienced friend said it was meh, so that's what brings me here.
@indigoaura : Hi indigoaura. Thanks for all your contributions, sending that powder to EC, reporting the results and so on!
What about trying those Q-Dance presses? They are supposed to be among the best of the Dutch megapills, and several people on this thread said they were magic. QDance presses are also a standard item, unlike powder. So if you, G_Chem, Le Junk, Hilopsilo and others concurred that Q-Dance was the cat's meow, that'd both falsify the initial claim and answer the practical question of most readers here. Right?
If the MAPS trial succeeds, I imagine the final product would be in pill form, like every other medicine. It'd be a pill weighing 240mg and containing 120mg of 99.5% pure MDMA*HCl and 120 mg of inert binder, or something similar.
So working backwards, a question for chemists: is it possible / useful to wash an OG checkpoint or qdance pill in acetone to remove the binder, so you're left with just MDMA*HCl plus synthesis byproducts, basically whatever the lab made and put in the pill. Then use an MDMA purity test from EZ-test to estimate how pure your sample is? Or even send it to EC. Indigo's sample was 80% pure, so how pure is the compound in those qdance pills in comparison?
Edata only tells you that a pill is 250 mg MDMA with a total mass of 500 mg. But that could describe a future MAPS pill with 250mg of 100% pure MDMA and 250 mg of inert binder, which is probably magic. Or 100mg of binder and 400 mg of very impure MDMA*HCl compound, which is likely meh.
If a pill is washed and revealed to have >95% pure MDMA*HCl, and it's STILL not magic, that'd be very interesting and surprising.
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An acetone wash wont fix the product. Mine was self synth acetone washed...
Indigo's sample was 80% pure, so how pure is the compound in those qdance pills in comparison? My sample of mdma crystal that was then sent via nmr was a WOPPING 97% via a private lab.. IT was pretty fucking pure and when column ran there was almost no loss/sepearation i was told that it was pretty fucking pure mdma. NMR found decerpancises and was ran after i told him you didnt get high for this meh did you..
Acetone wash doesnt remove amines... chances are whatever is block the high is an amine... are re crystallization, or column...
Distilling the freebase also maybe the issue...
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Very time consuming/lots of work. Very very low yeild. Finky synethsis vs other routes
This is insane. Is it possible the Chinese have developed a new drug that tests positive on GCMS as MDMA but is a different drug entirely? It is crazy to think that current MDMA is testing positive as just MDMA but has absolutely none of the characteristics associated with MDMA. Lovey-dovey, touchy-feely, feelings of love and empathy, completely dilated pupils, openness, loving everyone around you, incredible sex, next day afterglow, etc. etc. etc. None of those characteristics are present in today’s MDMA. And it’s not just some of the MDMA that’s like this, it’s most of the MDMA that’s like this nowadays. Finding magic MDMA today is like finding a needle in a haystack. Something has changed significantly and it’s widespread and commonplace. Whether it’s pills or crystals or powder, it’s pretty much all the same. There is one common thread here and it is the missing link to this entire tale. The manufacturers know. That’s for sure. And that’s why all of today’s pills have 250 mg in them versus 80 to 120 mg in pills for the past. This is crazy and frustrating. I can assure you the answer is very simple. The question is what the fuck is it and how the fuck long will it take us to figure it out? Such a sad time in the world for drugs. The beautiful and true cocaine high was completely ruined by levamisole. Now it’s MDMA’a turn apparently.
Welcome back bro! I’m back as well. I want to be present when the mystery is finally solved
My theory is also the safrole (or lack thereof). But time will tell.@vash445: Thanks for all your work on this thread! If your mdma sample had no effect despite being 97% pure, that's an extraordinary finding! In a scientific setting, all aspects would need to be replicated.
No effect: you personally observed 5 people take 1.3-1.5mg / kg body weight and show no pupil dilation? Like Shulgin said, people could take MDMA and say "nothing happened." And Hilo just said that even magicDMA didn't work for some of his/her friends. So while I totally believe your friend when they say "they didn't get high from this meh," the scientific standard of proof calls for more data before we go looking at NMRs.
97%: would be good to get independent labs to confirm this 97%. If someone personally dropped off a sample with saferparty.ch in Zurich or Jellinek in Amsterdam, and both of those labs said it's 97% MDMA*HCl, then that's established. If EC says it's 97, that works too. Even a consumer MDMA purity test from EZ could confirm purity in the 80-100% range, though it can't distinguish MDxx compounds.
97%: what's the history of the small lab that produced your 97% sample? If they've been churning 97% for years, then there is a strong prior that the sample is indeed 97%. On the other hand, if it's their first or second attempt, such purity seems difficult to achieve. Most crystal samples are reported at 50-80% pure. If the lab is experienced, has their earlier product been magic or meh?
Yes, I read that, but that's not what I was getting at. We simply want to determine the purity of the compound that goes into q-dance pills, so we use AW to remove the binder. Q-dance either is or isn't magic (still hoping some experienced rollers would make the calls on that...) And Q-dance compound maybe >95% pure or it may be 75.
If it's only 75% and meh -- no surprise there. In my mind, 135mg of 75% purity is not the same as 100mg of 100% purity, not when it comes to subtle effects. If the 75% compound happens to work (like the old Leuckart reaction), good for you, don't change a thing, but you can't draw any practical conclusions why it works or doesn't because everyone's 75% is different. Conversely, if 135mg of the 75% pure (impure) product was meh, you can't predict that 100mg of the same compound at 100% purity would also be meh.
Now if Q-dance's compound is both >95% pure AND magic, then all is well and as expected, chemically speaking. That's what G_Chem was saying, I think.
Le Junk's mystery would present itself only if the compound was ~100% pure MDMA*HCl (not MDPH, not another salt etc) and NOT magic.
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Le Junk, sir, your name will go down in the history books of MDMA! Tricky part is, them damn pills DO produce some or all of these effects. r/MDMA is full of saucer eyes and I personally observed the same. It's just that the more mental effects are not consistent or something. One time you may feel like it's the happiest moment of your life, and a simple touch feels more pleasurable than sex (tactile enhancement.) Another time the music may sound incredibly good. Or lovey-dovey, empathy, endactic, next day glow and so on. Some/many pills have some degree of these effects for some of the people some of the time!
I have another long-shot theory that one's experience may be somewhat affected by what you're told. If your source says this batch is fire, and you trust the source, it becomes a self fulfilling prophecy. And if you rolled hard on the same batch, or another batch with the same taste and especially smell, all those associations kick in again to enhance the roll, especially memory recall due to smell. Can an inert compound that merely tastes and smells like someone's long-loved batch of MDMA induce some of the same effects? Depending on the power of the individual's mind, there may be something to this, like Shulgin's story with undissolved sugar.
Welcome back bro! I’m back as well. I want to be present when the mystery is finally solved
Is it possible the Chinese have developed a new drug that tests positive on GCMS as MDMA but is a different drug entirely?
NO , Ive told you my meh MDMA WAS SAFROLE based... that is not it... That theroy DIED in NOV if you read the forum, my meh batch for sure... I know it is safrole based because I traded safrole for mdma and the chemist even complained he didnt get high
This has to be an impurity issue. because my meh MDMA batch after being column ran became clear NMR vs when it was dirty. The magic and meh became more inline once purified.
Whatever it is is an amine and not easily cleaned... This is what the evidence points to
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We had me, the MDMA cook, THE MDMA lab testing tech. AND and MDMA virgin 200mg nothing... 400mg was MEH for sure... PS we had NO EXPECTATIONS and this was private lab based MDMA... We thought it was his anti depression med but NOPE 4 people had no mdma effects it was meh until 400mg. The lab tech thought it was gonna be fire because it tested at 97%... this is much more then someone telling me it's fire or this is junk... because my expectations with the lab results saying 97% would tell me it's fire... it was not...
ALso I DID NOT TELL these people if the mdma was meh or magic everyone complained about it I only told the virgin it tested at 97% percent... Mine is private lab synth and private lab test results with this NMR... I trust MY RESULTS over EC/Dancesafe at this point. ALso we have no more of this meh to send into a public lab it was been purified and run thru the column already there was only like 1-2 grams.... You are just gonna have to take my word for it. ALso We don't need a second lab... The running of the column proved it was pure as he said their was not much impurity when he ran the column so... PLease read what we have done I would like not to repeat myself and clog the thread with theories we have already crossed off...
What that impurity is IDK, he misplaced the the stuff to test so we are back to square one unless someone sends me a few grams of meh to purify and see if the scan shows the same results...
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I basically bet my left nut it is a minor impurity that cann't be easily distilled or cleaned. It's what ALL THE evidence is pointing to with what we have collected. Our NMR of 3 mehs prove it is MDMA, it cann't be anything else...
However the picture of MDMA is unclear unlike the magic sample which have a perfect NMR
@mars2025 @Le Junk
However the picture of MDMA is unclear unlike the magic sample which have a perfect NMR
@mars2025 @Le Junk
Ok, that's convincing. I'd say negative result is well established via bioassay
As well you should. Every scientist worth their salt does. And yeah, I trust your data. But another lab still needs to confirm it to eliminate all doubt. Need to confirm that it's 97% 3,4-MDMA, not mixed with another MDxx etc. I don't know the specifics here, but that's just standard procedure in any research. Extraordinary claims require extraordinary proof, that sort of thing... And seeing no effects from 200 mg of 97% pure 3,4-MDMA in four different subjects is indeed an extraordinary claim.
Regarding a few grams of meh, I really think something like Q-dance's Skype or Checkpoint's Reddit (with pill binder removed via AW) would be the best candidates for further study. You'll never run out; your findings would be broadly relevant; you can compare your purity measurements to edata values without sending in samples and so on.
I'll defer to your expertise then, esp considering the nature of the proposed wager
But do you believe the same, ultra-potent roll-killing impurity is hiding in most samples of mehDMA today (those that are pure MDMA to begin with)? That the same impurity results with different precursors and different synthesis routes? And every sample or pill of magicDMA, like Hilo's 91% powder, has somehow avoided this one impurity?Again NOTHING WAS ADDED TO OUR BATCH... I KNOW EXACTLY HOW IT WAS SYNTHED down to mol's down to if they used methylamine. or nitromethane... I know VERY FINITE details about it there is no way of another MDxx AS WELL.. I assure you NOTHING was added, this impurity has drastic effects in mg dosages... I do not want to disclose much BUT I KNOW MORE THEN ANYONE about that batch the chain on it is VERY close
Here is the deal safrole was converted to MDP2P using benz wacker... MDP2P was animated with methylamine with Al/Hg. I know much much more but you get the picture.....
Also WE HAVE MUCH MORE TESTS then EC or DD will ever have. I assure you if WE CANT FIND IT they wont... and it will just show the same thing... this is the issue we seem to be encountering
And we don't need a second lab because the COLUMN proved 97%... what don't you understand? That when he ran the column the product showed it was clean 97% pure... almost no bands of contamination... we don't we a second lab there was other ways for us to show purity....
AGAIN this MEH mdma sample was TESTED every way thru sunday and we had a lot of people look at that report and come back it's MDMA.... TRUST me my meh IS MDMA and I know the way it was made... It was a bit funny on the NMR vs magic... when the column was ran after the product became clean....
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That the same impurity results with different precursors and different synthesis routes?
We have no idea... but reports of that popping up in our early lab results we found online... multiple routes impurities block the mdma high... please read the articles we posted earlier they post about 3-4 different routes explaining it...
We have no idea... but reports of that popping up in our early lab results we found online... multiple routes impurities block the mdma high... please read the articles we posted earlier they post about 3-4 different routes explaining it...
Ok, call me convinced. Suppose this 5mg impurity can completely negate the effect of 200 mg of MDMA. Do you believe the Dutch megapills have the same impurity? 200mg megapill will definitely roll, it's not nothing by any stretch, but some aspects of the high seem to be missing or reduced.
Are we dealing with two completely separate problems here:
1. Why some MDMA tests at 97% but does not work at all
2. Why some Dutch MDMA pills seem to be missing the "magic", while still providing a pretty good high
Can you explain that again?
Agreed, they won't. But there's a small chance that they would've come back saying your sample was not .97 but .60. Meaning something went wrong in your purity measurement or calculation. Don't ask me how. It's unlikely, but so is the proposed ultra-potent impurity. The purpose of getting a second purity measurement would be simply to eliminate this objection completely. Though I actually find your theory more likely, it won't be taken seriously by folks on that other chemistry board (I skimmed that thread), other researchers and so on, not without corroborating purity data from a known public lab.
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1. Why some MDMA tests at 97% but does not work at all
because these impurities block sert release in sub mg dosage..... and release 1/10 the ammount of serotin please read the report...
2. Why some Dutch MDMA pills seem to be missing the "magic", while still providing a pretty good high
Because binders and filler effect oral bioavailability . and good presser like checkpoint and the few other produce semi magic pills.
The FDA only requires that you get 80% to 125% of the drug into your bloodstream from a generic medication compared to the original drug. What’s even more concerning is that there are often many different generic versions of the same drug, and each of these may be different as well. Consider this: If you take a generic which only meets the minimum requirement and refill that prescription with one that’s at the maximum limit, you’ve potentially increased the amount you get into your body by as much as 45% percentage points – and you would have no way of knowing this from the labels, but it could certainly affect you. The opposite could also happen, and you would be getting a lot less drug than you were previously – which could also affect you.
TLDR basically the dutch are hiring pro pill pressers who understand pharamacology and binders and fllers and are pushing 125% + bioavailability with the binders/ dissolution... Binding a pill properly is HARD WORK... There are only a few true pro pressers is my guess tbh hence some magic... increase in meh but it is still meh...
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