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What is wrong with the MDMA available today?

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AutoTripper said:
Interesting that you still vomited from plugging. I would have assumed that the need to vomit may be greatly reduced by anal administration, but while I actually think about it right now I guess it makes sense to me how this would still be the case.
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Nausea is triggered by 5HT3 serotonin receptors in your stomach, so if you snort or plug the concentration at those receptors is going to be much less than having the dose absorbed directly close to them.
But if the dose is strong enough even the plasma concentration is going to trigger nausea.
 
I am relaying a 3rd party trip report from a gf of a friend:

A 38 y.o., female, 85kg, virgin MDMA user with no history of antidepressant nor stimulant nor psychotropic nor psychoactive substance use, reports a 1 hr come up and 3h duration of couch-sitting non-empathic expeience after ingestion of 150mg of tan MDMA crystals tested with a fresh Marquis reagent (straight to black) , subsequently dissolved in a glass of freshly squeezed orange juce after fasting for 6h. Her partner reports minimal mydriasis and no noticeable trismus and also no appreciable increase in music appreciation or change in the conversation flow.

The origin of the MDMA crystals is Utrecht, NL.
I did not perform a more complex analysis of this substance since they did not have anything left over by the time the news got to me.

I am relaying this unremarkable "trip report" because it concerns a virgin user - which is rare.
 
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Hilopsilo said:
2.) "The problem is something leftover in the MDMA" Depending on the production method chosen and skill of the chemist, leftover precursor or "organic impurities" are present in the final product and have an orders-of-magnitude impact on the subjective effects dose-for-dose. There is some literature on leftover precursor and organic impurities, but zero literature on the effects these might have when ingested.

It is not uncommon for MDP2P and other precursors (see Ecstasy Data) to be found in MDMA samples, it is possible that these interfere with the action of MDMA directly, but at the same time there is no evidence to say so. I do not believe it is possible that leftover precursor/organic impurities are the cause of differing effects purely due to diluting MDMA in a sample as they occur in such small amounts (usually, and in my own case).
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Would any of you be savvy enough to buy some analytic TLC Plates and solvents to perform Thin Layer Chromatography at home.on your substances ?

You can use Google to find a vendor of cheap "TLC plates" in your country. They are easy to buy and the procedure can be done at home in a glass with a dropper, some solvent and a UV light source (e.g. disco black-light or this). e.g. see this video or this video.

It would be ideal if you could test the MehMDMA and magic-MDMA side-by-side and post a photo of the spots on the TLC plate,
 
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A 38 y.o., female, 85kg, virgin MDMA user with no history of antidepressant nor stimulant nor psychotropic nor psychoactive substance use, reports a 1 hr come up and 3h duration of couch-sitting non-empathic expeience after ingestion of 150mg of tan MDMA crystals tested with a fresh Marquis reagent (straight to black) , subsequently dissolved in a glass of freshly squeezed orange juce after fasting for 6h. Her partner reports minimal mydriasis and no noticeable trismus and also no appreciable increase in music appreciation or change in the conversation flow.
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That sounds right, and I don't doubt it at all. I don't doubt that we could take dozens of virgin drug users an give them 150 mg of MehDMA and they would all have the same result.
 
I think even pharmaceutical-grade MDMA won't be for everyone. A lot of people have tried it once and never again. There's no guarantee that taking some drug equals good times or a profound or enjoyable experience.

If someone is 38 with no history of psychoactive drug use, I'd say that it's probably just not their thing.
 
I think even pharmaceutical-grade MDMA won't be for everyone. A lot of people have tried it once and never again. There's no guarantee that taking some drug equals good times or a profound or enjoyable experience.

If someone is 38 with no history of psychoactive drug use, I'd say that it's probably just not their thing.
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No offense, Kaden, but that is not very scientific.

I don't doubt that there are people out there who would not enjoy/fully experience MDMA, due to genetic variations, underlying conditions, etc. But to say that a 38 year old would be incapable of experiencing the effects of 150 mg of MDMA just because "it's not their thing" is illogical.

I've brought vodka up before because I think it is something most people understand. If someone who had never been drunk drank 8 shots of vodka, they would get drunk. They might or might not like the experience, it might or might not be their thing, but they WOULD get drunk.

Someone who has never rolled before SHOULD experience peak effects off a 150 mg dose unless there is an underlying issue. To try to argue against that is to disregard published scientific data on the topic as well as decades of anecdotal accounts. This 38 year old woman should have rolled, and it should have been observable by the people around her. Whether she found it to be "her thing" or not is a totally separate issue.
 
indigoaura said:
No offense, Kaden, but that is not very scientific.

I don't doubt that there are people out there who would not enjoy/fully experience MDMA, due to genetic variations, underlying conditions, etc. But to say that a 38 year old would be incapable of experiencing the effects of 150 mg of MDMA just because "it's not their thing" is illogical.

I've brought vodka up before because I think it is something most people understand. If someone who had never been drunk drank 8 shots of vodka, they would get drunk. They might or might not like the experience, it might or might not be their thing, but they WOULD get drunk.

Someone who has never rolled before SHOULD experience peak effects off a 150 mg dose unless there is an underlying issue. To try to argue against that is to disregard published scientific data on the topic as well as decades of anecdotal accounts. This 38 year old woman should have rolled, and it should have been observable by the people around her. Whether she found it to be "her thing" or not is a totally separate issue.
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It could also be argued that due to the effects profile of MDMA, I guess you can only get so far as not liking that you like it.
I mean that after the experience a person might say that it was too pleasurable, that it makes you say things you should not say, think things that you should not think (AAAH THE HORROR), feel too much confidence in others, that you talk silly and make terrible faces. Whatever. But it would be very hard for MDMA to be causing negative/feelings.
 
When I started doing E, my best mate and partner in crime never seemed to 'get' the experience. We've taken the same pills many a time and whereas I'd be bouncing off the walls grinning like a loon, he'd be flat on his back on the sofa monging out. However, he still used to get massively dilated pupils and chew his face off.


@Phobos in answer to the question on your Sig - 'the brain, heart or dick, it depends upon the copper....'
 
F.U.B.A.R. said:
When I started doing E, my best mate and partner in crime never seemed to 'get' the experience. We've taken the same pills many a time and whereas I'd be bouncing off the walls grinning like a loon, he'd be flat on his back on the sofa monging out. However, he still used to get massively dilated pupils and chew his face off.


@Phobos in answer to the question on your Sig - 'the brain, heart or dick, it depends upon the copper....'
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Aw come on in the UK most cops are pure gold compared to Italy, you're spoiled.
 
BTW did your friend have a generally high tolerance for all drugs? Or was it just MDMA that wouldn't be stimulating for him.


F.U.B.A.R. said:
Ah, seeing as you're in Italy, then my answer is 'the brain, the heart and the dick'. Oh, and 'the soul'... ;)
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I've invaded your country years ago.
 
Phobos said:
BTW did your friend have a generally high tolerance for all drugs? Or was it just MDMA that wouldn't be stimulating for him.
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No, he was a fuckin lightweight tbh :LOL:. The come up seemed to hit him very hard, but he'd still get there in the end. I guess my point is that while people can react to drugs very differently, good drugs are undeniable...


Phobos said:
I've invaded your country years ago.
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Happy to have you mate (y)
 
Yep, true that, in particular MDMA produces a smaller variation in effects between people compared to many other drugs.
Speed can make some talk forever while they pace and others will sit down all calm and silent.
Psychedelics can produce very evident problems at surprisingly low doses for some people.
 
If someone is 38 with no history of psychoactive drug use, I'd say that it's probably just not their thing.
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You interpret this as:
a 38 year old would be incapable of experiencing the effects of 150 mg of MDMA
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Not sure how you got that from what I said, but that's okay because you kind of demonstrate my point:
Someone who has never rolled before SHOULD experience peak effects off a 150 mg dose.

This 38 year old woman should have rolled, and it should have been observable by the people around her.
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People have expectations of how they believe drugs 'should' affect them. It clearly doesn't always work out like that.

To try to argue against that is to disregard published scientific data on the topic as well as decades of anecdotal accounts
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So I don't understand why you are arguing with it? The anecdotal report that was just offered, you are contesting the legitimacy of, just like all the lab tests and the experience reports outside of this thread which don't fit in with your 'something is wrong with the MDMA' belief.

If you believe that something 'should' have happened in Glubra's anecdotal report, talk to him.
 
Phobos said:
MDMA produces a smaller variation in effects between people compared to many other drugs.
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I would agree with this, but I think there is still a lot of room for variation. My eyes tend to light up like fireworks on MDMA while I chew gum like I'm sponsored by Wrigley's™.

Some of my friends will have twice as much of the same stuff and sit calmly at their computer messaging people all night.

Sometimes they really like a batch that I thought was a bit mediocre, other times it's the other way around. Then, sometimes there's a batch that everyone seems to rave about and remember forever.
 
AutoTripper said:
Interesting that you still vomited from plugging. I would have assumed that the need to vomit may be greatly reduced by anal administration, but while I actually think about it right now I guess it makes sense to me how this would still be the case.
Click to expand...


Phobos said:
Nausea is triggered by 5HT3 serotonin receptors in your stomach, so if you snort or plug the concentration at those receptors is going to be much less than having the dose absorbed directly close to them.
But if the dose is strong enough even the plasma concentration is going to trigger nausea.
Click to expand...


I think I was mixing lots of ket with it which probably contributed to that. Also threw up from that batch when eating a higher dose and plugging it with 2cb. I notice plugged mda hits real fucking fast allot quicker than varies 2cs I've plugged. I fully peaking within 10-15 mins. Probably that jolt of it all hitting me at once is what did it in but also threw up from eating the stuff. Really miss that stuff wish I could of got some mdma at the time to try and combining them to see how the experience compared to rolls I've previously had with pressed pills years before.
 
phenethylo J said:
I think I was mixing lots of ket with it which probably contributed to that. Also threw up from that batch when eating a higher dose and plugging it with 2cb. I notice plugged mda hits real fucking fast allot quicker than varies 2cs I've plugged. I fully peaking within 10-15 mins. Probably that jolt of it all hitting me at once is what did it in but also threw up from eating the stuff. Really miss that stuff wish I could of got some mdma at the time to try and combining them to see how the experience compared to rolls I've previously had with pressed pills years before.
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Mh, really curious to hear if someone can report about a combo of MDA+ MDMA in known amounts.
 
@Kaden_Nite , you are not understanding my post.

I 100% agree with the anecdotal report. It is totally believable to me and lines up with the last 116 pages of discussion. I am not discounting the legitimacy of it at all. It is yet another anecdote to add to the pile. The woman did not take "magic" MDMA. If she had, her experience would have been different.

You then had an alternative take on the anecdote, and came along and said that drugs must not be her thing. It seemed to be an explanation for why she did not roll, especially since it immediately followed your statement:
I think even pharmaceutical-grade MDMA won't be for everyone.
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Again, these phrases like "won't be for everyone" and "it's probably just not their thing" are not explanations for why this virgin user did not roll. They are not scientific explanations. Drugs have known effects profiles.
 
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