It was an induction, yes, but with one of the volatile fluorinated ethers as the secondary drug, sevoflurane from the smell and taste of it, I had told them not to use any barbs on me (I have my reasons, primarily shit veins and I didn't want to risk any extravasation due to the highly alkaline PH of barbiturate sodium salts as are used for IV, as the result would be a nasty burn. With it being an inhalational agent that gave me enough time to evaluate it a bit better and more control over things. And I wouldn't MAKE my own remifentanil, that would be just begging for trouble of a most unpleasant sort. I doubtless COULD do so but damned if I'd A-put my family at risk from traces of the stuff and B-want to end up physically dependent on something that would have to be redosed every few minutes, or else my walk around with a fucking IV bag attached to me. Waiting for the day I couldn't find a vein, and then end up insta-screwed.
And of course given the short duration of action, I'd never sleep again, literally, if it were not for using an IV bag every night or syringe driver. No thanks. Besides the fentanyl family really aren't to my taste. Too much tachyphylaxis, too cold and clinical, all the warmth of an inuit nun mother superior's icicle-encrusted cunt IMO. And not much euphoria either. Lofentanil and alfentanil (the latter again in hospital although both before and after a surgery so the second time around with it I got to get a proper taste of it, so to speak since they redosed me after I came around)
For an opioid, my aims are-long or at least intermediate duration of action, big IV rush, potent by weight but not TOO potent, not so damn strong one can't viably dose it safely. And if possible something with some NMDA antagonism. There's too much risk in making the fentanyl derivatives, I've more chance of getting away with it, due to tolerance, but other people haven't.
And as for little set up..heh I wouldn't say that. Its invaded four rooms thus far, five if you count having to keep my microscope away from everything else and still got the crate my rotavap came in in the porch for want of anywhere else to put it

I'm sure other people have better, but its definitely far from primitive

And I do have pretty good connections for reagents. Things like red P, nitroethane, acyl halides/anhydrides etc.? not a problem. For the most part if I need it and can't make it, or don't want to for some reason (chloroform being a good example, since the haloform reaction is so bulky and such a pissy return based on a small volume of acetone and masses of hypochlorite, along with its being damn exothermic and a nuisance in general on a large scale. Could make it easily, have done, just don't want to, not when I'd want several liters at a time and don't want to spend the next few days making batch after batch and ending up sleep deprived even more than usual) I can buy it (not specifically CHCl3, I mean, just, reagents and solvents in general. Got a pretty good selection of glassware and other equipment (E.g rotavap, vacuum pumps, quite a lot of mag-stirrer hotplates, microscope, power supplies, that kind of thing) and am not averse to hacking stuff together either when needed. Plus a pretty good workshop for metal and woodworking, including a metal lathe, drill-press, bench grinders, routers etc. All manner of the kinds of useful tools your average bee can't live without
And as for desomorphine, haven't tried it, yet. Its high on my to-try list though. I've heard a lot of good things about it, as long as one doesn't resort to nasty ass shit like the 'krokodil' of the russian peasantry. Apparently after chlorination of morphine with SOCl2, (this step is pretty easy as long as you are comfortable handling thionyl chloride, which admittedly isn't the nicest of reagents, but its certainly not the worst, and it IS a very useful chlorinating agent indeed, I rather like it, as the breakdown products are HCl and SO2, both gaseous so easily removed from the system, and it reacts very quickly)
I've tried the intermediate alpha-chloromorphide, which was rather weird stuff to say the very least. Didn't get round to reduction to desomorphine (apparently colloidal palladium in isopropanol at atmospheric pressure or with just a balloon to provide hydrogen pressure is enough, and presumably other Pd catalysts. Platinum however is too active and instead gives the tetrahydrodesoxymorphine derivative rather than the sought dihydrodesoxymorphine.) Because I got sidetracked investigating the chloromorphide itself, since as far as I could tell it hasn't really been tested at all, either in animals or people, I couldn't find a single paper on its biological activity anywhere, although not for want of trying, and to my great surprise it turned out as some weird arse kind of psychostimulant, quite unlike amphetamines, DARIs etc., and likely a convulsant in overdose (I stopped trials due to clonic twitching in the hands and feet at the highest doses tested)..weird stuff. Next time, its going all the way, though. Wanted to try desomorphine for ages, since it has quite the reputation)
Hm, and on another line entirely, anyone ever accidentally IV'ed? just went to IM a dose of morphine, a bit over 400mg, and without looking got rather more than I bargained for, first thing I knew was a funny taste in the back of my mouth and a LOT of histamine release, followed by a big rush and not long after, nodding right off before ending up totally asleep. Seems like I went to IM in my arse cheek and accidentally drove the needle through skin and muscle right where there was a vein at just the right height for the needle to end up in it, resulting in my giving myself a pretty big fucker of a hit for one I wasn't expecting
