I should add that I eyeballed the 2C-D but I have done it numerous times- it was a standard oral dose for me. 2C-D is better snorted though ridiculously painful.
i.m. 2CD is where it's at, although don't be like me and
go to 40mg the first time, not because I had any sort of "bad trip," I doubt it's really that possible to have a serious freakout on this exceedingly forgiving, gentile, and not too potent compound; it's one of the few RC's I wouldn't have reservations about eyeballing, p.o. doses are ridiculously high and for me wasteful -- remember I'm talking about 40mg
i.m. and I estimate by the seat of my ass that that's equivalent to 120-160mg p.o., the lowest dose I would really consider worthwhile is 80ish mg
however don't listen to me as I am particularly hardheaded to 2C-drugs in general (80+mg 2C-B gets me more or less to about where I want to be, p.o.; 2C-D twice that at the least, up to 2 points, this is probably a quirk of my chemistry [definitely not my drugs, as other people had them too, and took reasonable doses] so don't try this at home), I don't know about nasal doses though.
I used to love snorting small lines of 4-HO-MiPT (repeatedly, throughout the night), 4-HO-MET being a little more potently, you couldn't probably do it all that safely, OTOH on one occasion I mixed ketamine, mephedrone, and 4-HO-MiPT in approximately equivalent doses (maybe a 10:15:2 ratio or thereabouts) in a mortor and pestle, enough for three for a night, and it was an incredible experience; waste of good drugs to an extent on the 4-HO-MiPT as tolerane is a big factor (so I kept hitting key bumps of 4-HO-MiPT as a booster in addition to lines of my cocktail, again, don't try this at home) ... 2C-D and 4-HO-MiPT are good together though, as is 2C-D (Shulgin's "tofu") with just about everyone else.
2C-C I didn't particularly care for, it was emotionally neutral in a particularly aggressive way, if that makes sense, the first time that I tried it, which was, rather emphatically, not what I was going for at the time (I was with the most fucking adorable 18 year old hippie chick with a pixie cut and an active imagination, she turned out to be the daughter of [spoil]rich/famous/smart[/spoil] and [spoil]1980s cover girl[/spoil] which in and of itself was pretty nuts but needless to she was ... yet the drug kind of inhibited me from, like, appreciating the situation, yeah?) but anyhow, I'd consider it, like, tofu with a particularly unpleasant texture, insufficiently congealed and too much water, something like that ... weird ass drug ... I'm surprised people still make it ... 2C-M (a/k/a 2C-D; I'm trying to get more people on the train of calling it 2C-M (as in
methyl, as also in DOM), the D stands for desoxy-2,4,5-TMPEA but 2,4,5-TMPEA is not a drug of any relevance so I think we'd do better to maintain consistency in nomenclature across the α-Me/non-α-Me substitutions), on the other hand, is absolutely my favorite simple 4-substituted phenethylamine (not including, that is, the 4-thio-phenethylamines; which I really had a particular affinity for and
really miss, although I guess they don't distribute a lot of 2C-T-7 anymore given how it gained it, and the scene's, infamy way back in the Stone Age 90's, -21 was pretty cool though, -2 pretty much sucked though IMO)
I'm really curious about multi-drug low-dose combos. I've wondered what would happen if one was to consume say 2mg of 2C-D/E/I/B/C/D each. Would this add up to something else, would it be dangerous, would it simply not work? I did something akin to that by taking 3 different lysergamindes (LSD, 1P-LSD, ALD-52) getting up to an assumed 150ug of lysergamide but it didn't feel any different to just taking 150ug of either alone. I did. But I just wonder if a perfect ratio of the different flavour 2C-x's could do something cool.
From a strictly theoretical standpoint I don't really see why this shouldn't work, although I haven't tried something exactly akin to what you're talking about, lots of us have tried multiple psychedelics at the same time (obviously) and (
a) tripped
harder and (
b) had a trip of a different
character than if they were to take one or the other; now of course the big question is about threshhold doses adding up to be something active, and I could only assume that they would, although it's not something I've tried experimentally. It is so for pretty much every other class of drug (take a bump of heroin and a little morphine, or some meth and some dexedrine, or a shot of booze with a small benzo dose, or whatever), but given the uniqueness of the psychedelic recepterome, the tendency to build tolerance, etc. it would be a different sort of adventure. I'd wager a decent sum that you'd have an appreciable but not overly intense trip from taking, say: 10mg 2C-M/7.5mg 2C-B/5mg 2C-E/5mg 2C-I.
Hyper-customization of drugs is held by a lot of theoretical types to be the future, but that might already be accessible in DYI capsule form, we could even invent a nomenclature, say, call the aforementioned example a 2.5mg dose of [font="Cambria Math;Cambria;Times New Roman"]2C
ς {4
M:3
B:2
(C,I)}[/font]. This sort of stuff already finds (somewhat nefarious) application in the creation of synthetic cannabinoid "spice blends" and so on, but their purpose (even if clumsily executed sometimes to a fatal degree) is in fact to provide an optimal experience by combining, at times, more than one drug of the same class with different effects on the human recepterome.
Contrarily, in medicine, psychopharmacology in particularly but really everywhere, polypharmacy is generally held to be a Bad Thing, however, we can sometimes get considerable benefit from placing a patient on two antipsychotics (for example; sometimes even three, especially if the third is Clozaril), because they have, again, different affinities (albeit quite often the opposite ones for the same receptors.) The problem of side effects, of course, is increased by the number of drugs.
Also, I would not expect the dosage-response curve to be lineal, and would expect you'd have to do a considerable amount of mucking about with the dosages to come out with something optimal, and could
not assume (as I did in the above example, which I give as something which is probably safe but by no means optimal) that roughly subjectively equivalent doses put together would give an experience equal to the sum of the doses but with varying characteristics, that one would have to find out empirically.
But, I think it is safe to say, this would be a way to devise "new drugs" from combining smaller doses of old ones. Whether this would be economical is uncertain and probably doubtful (although careful choice of drugs with more subtle interactions might allow for selection of potentiating drugs, although something like 2C-T-7 mixed with tryptamines, while given MAO-inhibiting properties of the latter might be promising, might also be dangerous on the way to be really cool, and one would have to presume dangerousness and tread very carefully.) I wouldn't be surprised, though, that there would be a couple of [font="Cambria Math;Cambria;Times New Roman"]{n
d · · · m
dm}[/font]-type drugs that would be quite rewarding! And with doses starting low, I cannot imagine it being unsafe. Perhaps a worth area of exploration for people who have a variety of little vials going on and want to try something
really new; just remember my reservations and the universal reservation to "start low/go slow"