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200 mg dose safe?

Generic84

Generic84

Bluelighter
Joined
Dec 27, 2013
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130
I have done MDMA approximately 10-12 times. I was wondering though, is a starting dose of 200 mg at all dangerous? I think I've dosed that much or more once or twice, usually around 175. Thanks.
 
Clocktower said:
Certainly yes for some people, maybe yes maybe no for others.
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What would be the upper limit of a safe dose, do you think? Would 160 mg be safe? I always follow rollsafe.org on supplementation, vitamin C an hour before with grapefruit juice, one tums 30 minutes prior, vitamin C 2 hours after, usually one redose that's half of the original dose an hour and a half later.
 
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Thinking of 175-180mg next time. I think that has been my best dose to get floored. Redose an hour and a half 90mg.
 
Taking these high dosages just increase your tolerance, really. 150mgs should be enough, with maybe a 50mg redose later is the best bet, really.
 
Nicholai said:
Taking these high dosages just increase your tolerance, really. 150mgs should be enough, with maybe a 50mg redose later is the best bet, really.
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Thanks, think will keep in that range. I just want the best possible results, you think 150 is enough to floor someone? I want to get a real decent roll.
 
It used to floor me for sure, yeah, back when the pills were really good(circa 1995-2000).
 
200mg is not a dangerous dose of MDMA. In general for those without a tolerance it is simply not needed and could be too much and you may end up floored /unable to dance / very out of it etc but it's not a dangerous dose.
 
Bearlove said:
200mg is not a dangerous dose of MDMA. In general for those without a tolerance it is simply not needed and could be too much and you may end up floored /unable to dance / very out of it etc but it's not a dangerous dose.
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Hmm, maybe will dose 175-180, redose an hour and half later half like 90. Happy medium. Going to drink a glass of white grapefruit juice 6 hours prior and then an hour prior to dosing, 1,000 mg vitamin C. Half an hour before one TUMS. So I'm sure the grapefruit juice will potentiate it.
 
Generic84 said:
Hmm, maybe will dose 175-180, redose an hour and half later half like 90. Happy medium. Going to drink a glass of white grapefruit juice 6 hours prior and then an hour prior to dosing, 1,000 mg vitamin C. Half an hour before one TUMS. So I'm sure the grapefruit juice will potentiate it.
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WGFJ does not inhibit CYP2D6 at any concentration you could ingest which is the main cytochrome responsible for MDMA metabolism. It does inhibit CYP3A4 -- which has a very minor minor role in MDMA metabolism.

The acid content of GFJ and the Ascorbic acid could actually cause you to excrete MDMA at a higher rate than normal (MDMA is a base -- acidic urine excretes bases faster).

Bottom line -- GFJ will not potentiate MDMA

Things that will:

sexual stimulation (orgasm if achieved is the best) on the come-up or during a wave while peaking

starburst fruit chews

cigarettes

massages

standing in front of the speakers at a rave (may cause deafness)
 
shugenja said:
WGFJ does not inhibit CYP2D6 at any concentration you could ingest which is the main cytochrome responsible for MDMA metabolism. It does inhibit CYP3A4 -- which has a very minor minor role in MDMA metabolism.

The acid content of GFJ and the Ascorbic acid could actually cause you to excrete MDMA at a higher rate than normal (MDMA is a base -- acidic urine excretes bases faster).

Bottom line -- GFJ will not potentiate MDMA

Things that will:

sexual stimulation (orgasm if achieved is the best) on the come-up or during a wave while peaking

starburst fruit chews

cigarettes

massages

standing in front of the speakers at a rave (may cause deafness)
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You seem to really know about this. I was just going by what rollsafe.org suggested. I guess will skip the Grapefruit Juice. Marijuana can enhance as well right? Thanks.
 
200mg isnt a "Dangerous" dose, however its a very strong one. I wouldnt recommend 200 starting, floor city if you got the goods. I suggest 120 initial
 
well 200mg of product is almost definately less than 200mg pure MDMA - but eitherway not likely dangerous but certain too much for many - my GF finds 90 mg plenty for example - I really don’t think she would find twice that good and not many really need 200 I think.
 
Grapefruit juice supposedly allows MDMA to be absorbed more slowly, from what I understand. Therefore, prolonging the roll. If you would like to potentiate it, you could try a regimen of racetams or noopept. Personcally, I've tried piracetam for 2 weeks prior and found not much of a difference; however, many others have found it to work great. Most recently I will have been taking noopept for a month and will roll soon. Also, 200 mg what my girlfriend and I take everytime. We love the floored feeling and 69'n is amazing :)
 
2007YZFR6 said:
Grapefruit juice supposedly allows MDMA to be absorbed more slowly, from what I understand.
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It will not cause MDMA to be absorbed more slowly.

Grapefruit juice is thrown around because it does inhibit CYP3A4, one of the cytochrome P450 enzymes that metabolizes MDMA. --

only problem is, it only plays a small role in MDMA metabolism.
 
I was mistaken, rolaids or tums help with prolonging the roll, and nausea. This is what rollsafe says, 1x Tums/Rolaids (Not for harm reduction, unlike other supplements. Increases stomach alkalinity which prolongs the roll).
 
2007YZFR6 said:
I was mistaken, rolaids or tums help with prolonging the roll, and nausea. This is what rollsafe says, 1x Tums/Rolaids (Not for harm reduction, unlike other supplements. Increases stomach alkalinity which prolongs the roll).
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There is no such thing as increasing stomach alkalinity -- your stomach will always be acidic maybe less acidic but certainly not alkaline

3 tums dropped in a cup of lemon juice (which has a pH of 3) only raised it to 5 (still quite acid); now consider that your stomach is normally at a pH of 2, and pH is a log scale -- you can see that 1 tums won't do dick

what they are probably thinking about is

Amphetamines are excreted more slowly from alkaline urine.

A tums will not prolong the roll that is BS
 
2007YZFR6 said:
Ha ok, I will let RollSafe know that they should edit their web page.
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Whatevs. It would be more prudent for you to actually educate yourself on some basic science and chemistry, than be snarky.

Or spot the hole in the logic of "a tums make the MDMA absorbed more slowly so it lasts longer."


A full stomach makes MDMA get absorbed more slowly and also increases stomach pH much more than 1 tums will, but the difference in length of roll from come-up to end is pretty much the same.

BTW, I bet if you take a tums, then drink a glass of juice with the dose dissolved -- you will come up just as fast as if you don't take the tums. Just Sayin'
 
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