I take 70mg Vyvanse a day. I've been on it a long time. I started at 40 mg a day. Even at that dose, I felt pretty good ADD coverage. My energy was up and I was pretty happy. The problem was it didn't cover a full day, so I was eventually moved up to 70mg.
70mg is a nice dose. For me, it lasts a solid 8 to 10 hours. It lasts this long and I've been on it for roughly 3 years.
Tricks I've learned while using this medicine include taking a medication break once in a while, a good 2 to 3 day break, makes the medicine feel new and fresh to me.
One thing that helped me continue to get the most out of this drug was/is tuning into it. I don't take the effects for granted and I make sure my mindset is right before I use the drug.
I can't really explain being in the correct mindset, but if I have a lighter attitude, this medicine continues to effect me strongly.
This is a very nice medicine. If you want to really tweak TFO, use Adderall or Dex, like the above posters have suggested.
IMO, most of the time, the comedown is not bad at all in comparison to other amphetamines. I find benzodiazepines make the comedown very easy or almost non existent.
It's important to only take what you need, in order to avoid tolerance issues. Cal,Mag,Zinc pills and low dose DXM doses (30-60mg) on off days, I believe help keep tolerance at bay.
I couldn't help try to shed a light on an excellent medicine. Use wisely.