The dose is too high, IV is 3-4x stronger than buccal administration at the very least, and being that it causes local numbing it's possible it's a local anaesthetic and constricts local blood vessels, making a missed shot more likely to cause necrosis or other problems (think krokodil pictures in worst case scenarios, a nasty abscess or maybe if you're real lucky nothing at all if you get away with it) - though I think with the small amount of material the risk would be low for necrosis.
The real risk comes from the seizure likelihood injecting such a dose. I now know 6 people who I've known for years in real life who have ended up in hospital, on the edge of death, all from NBOMes. Doses were all between 2 and 3mg (most around 2mg) with one exception being 3.5mg. 2mg can very easily cause a seizure which can very easily kill you, and the vasoconstriction and strain on your heart and blood pressure at such a dose can be pretty high too.
1mg IVed is more like 4mg+ buccal, and I would never recommend someone take 2mg buccal 25I after nearly losing one of my best friends to such a dose, it's like eating a gram of Tramadol, a lot of people will get away with it, and so a lot of people will post that such doses are safe, simply because seizures are not like say CNS depressant overdose, they're not a sure thing at a certain dose, it's just once you reach a certain dose, there is a very real, and not at all unlikely chance that you will actually
die. I'm not trying to scare you, I'm being frankly honest.
If you want to take a psychedelic that'll give you crazy visuals like the NBOMes, not cause elevated blood pressure or heart strain in the same manner, and not cause you to quite possibly have a fatal (i.e. you die) seizure just by shooting up 0.4-0.5mg or so, then take LSD or AL-LAD or a 2C-x or Mescaline or DMT or some other psychedelic that isn't loading up a gun with some bullets and pulling the trigger to your head and hoping you get an empty chamber like high dose NBOMes are.
No, IVing 1mg of 25I-NBOMe is not safe. I would not recommend IVing 25I at all for the above reasons since IV makes all these things more likely, but if you ignore my advice and choose to IV anyway, 200mcg (0.2mg, or less) should be enough for a strong trip if you have good material to begin with. To do this, place your blotter in 1ml of water (or something your particular salt/freebase of 25I is soluble in, look it up if you dont know, or ask here), leave it to soak for an hour or so, then take the blotter out, take a micron filter, draw up 20ccs of water (0.2ml) and there's your 200mcg~. You can use a cotton bud or cigarette filter if you can't get a micron filter, but for the dollar the filter will cost you, you avoid getting ink and some of the bacteria that will be all over that blotter, who knows how many hands it's passed through. In fact, considering how much blotter is handled, unless you know everyone down the pipeline and that they have nothing you could catch, I'd avoid IVing without first sterilising the solution. At best you can add a drop or two of Ethanol but remember the total volume of solution so you can divide to get your proper dose accordingly. Don't try to heat to sterilise the solution as this will likely damage the 25I.
Please reconsider the whole idea, if you want a mindblowing IV psychedelic experience, grab some clean and pure DMT fumarate and enjoy
Also, if you have never IVed before, do not even remotely consider IVing anything to begin with is my advice. I know in all the bullshit they teach kids in many countries about most drugs that's so horribly inaccurate it actually *encourages* kids to try drugs since they see their education on them is laughable - there was only one thing I remember in the big bad anti-drug leaflet that was 100% accurate - no, when I tried heroin, I didn't get hooked first try, I never took it again (though I was already an opiate addict and opiates will get you hooked, just in a different manner, so don't take this as me condoning them in the slightest aside from for legitimate pain, maintenance, or other genuine reasons for their use), no weed did not make me want to rush out and try every drug under the sun, being moved country to one of the drug capitals of Europe because my mother said we had to move to get me away from my "dealer friends" made me want to rush out and try every drug under the sun, no dealer ever tried to give me "free samples to get me hooked", tripping doesn't make you see people who aren't there (well not psychedelics anyway, stim psychosis and deliriants.. well thats a whole other kettle of fish)... but the moment I pushed down on the plunger successfully the first time, I was a changed man and I don't know if or when I'll ever stop thinking about needles.
Psychedelics (well, not NBOMes, but other psychedelics) are the only class of drugs I view as *solely* beneficial if used by the right people at the right time in the right place, don't go from a psychedelic user to an IVer if you weren't already. It doesn't necessarily matter what you inject the first time, it's a surreal thing I can't for the life of me explain.
