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The Big & Dandy Methoxphenidine / MXP / 2-MeO-Diphenidine Thread

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Thinking of ordering some to help ease Opiate Withdrawal and PAWS. looking for only small doses (25-35mg) anyone have experience with MXP and opiate WD/PAWS? or not to derail the thread but what would be the best aryl/disso. for alleviating some aspects of opiate WD/PAWS?
 
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Actually before checking this thread I started with a similar warning in the 3-MeO-PCP thread. And I just added one to the OP of this thread, slightly differently. I have experience with dissociatives including severe PCP-like types but not this particular one, so if you are still motivated help us out making the warnings as effective as possible. Please consider reactions / dosage suggestion etc other people posted about or suggested as well, not only your own response... all in all the most problematic reactions / experiences can be the most helpful to base our prevention on, those we want us all to avoid. :)

I would like to also have something added on the front page along the lines of 'methoxphenidine has shown a tendency to intoxicate users to different extents off of the same dosage level as previous dosages even in those tolerant to it and similar substances' 'methoxphenidine has shown a tendency to be metabolized very slowly and can greatly intoxicate someone who has not eaten properly while the same amount dosed on a full stomach may not hit as hard'. Something along those lines needs to be stressed. Plugging 100 mg didn't get me too far out there with a normal diet but on the otherhand I have went WAY out there with 100 mg oral on a different time with an empty stomach, much further than the equivalent dose plugging.

I have toyed with the eating normally vs fasting and dosing and have found that the effects are GREATLY potentiated when nothing much is eaten. This can manifest itself in very confusing situations by sneaking up on you and hitting you very hard ~6 hours (or more) in after eating the dose. I would say it is a very safe bet to say this stuff has a long half-life and is not metabolized very quickly. My suggestion to those who are thinking about giving this a go is to start low and only do it when you have AT MINIMUM 1 day free AFTER the first day of dosing. If you have weekends off want to do it, I would advise starting on Friday if possible and only redosing very late on that Friday or early on Saturday (once you are familiar with the duration, don't redose when first trying, this has been stated multiple times by many in this thread).

I have found through 3 different weekend experiments that 100 mg on Friday at midnight followed by 40 mg 18 hours later will make for a very nice Saturday and Sunday FOR ME. I have also found that 100 on Friday followed by 50 mg 18 hours later then 50 mg 6 hours after that will carry on for 2-3 days from time of first effects. Dosing 100 mg initially and then doing 100 mg more 12 hours later will have about the same reaction although metabolism and diet will determine length and strength. I was going for about 4 days off of 100 mg initial dose at 6 PM on first day followed by 50 mg 10 hours later and then 40 mg 24 hours after the first dose. This was on an emptier than normal stomach for the weekend and I was intoxicated to varying degrees from about 2 and 1/2 hours from first dose until late 4 days later. Yes you read that right, I was feeling it from Friday all the way through Monday and probably a little into Tuesday. This is where I see potential for trouble for those who are not careful and don't clear their calendars.

I found myself intoxicated (but functional) in places that I did not want to be intoxicated at and had luck on my side in being able to handle things easily.
This was all with doses totaling less than 250 mg over the course of multiple days and I can say that I have a tolerance to MXE and amphetamine and hydrocodone and this stuff still managed to put me a little too far out despite said tolerances.

I have a suspicion that this stuff stays around in your system in fat and releases itself when you don't eat enough. Others have commented on its long duration and I know there has to be some explanation as to why it changes its effects profile so drastically even with 'familiar' dosages. I strongly caution those who want to research that to do so very gradually.

On a different note I did find a 'hole-like' state during the last trial of 100 mg initial dose followed by 50 mg 10 hours later and then 40 mg 24 hours after the first dose. This state manifested itself probably 36 hours from initial dose and and I was flirting with an out-of-body experience while laying in my bed. I would say I was 50% successful in getting myself OOB but I fell asleep before I could get more control over the feeling. I was very surprised by this as I had used a similar amount in a shorter timeframe before that experience and did not get this 'hole-like' state then. I would like to potentially revisit said state but I am going to have to try a few different ways to go about getting there as this stuff does not act the same way more than twice for me and even then those dosages can be felt completely differently than previous dosages of the same amount.

This stuff is very hard to pin down, I still like calling the state 'phaded' but it doesn't really have a consistent profile every use. Hopefully this is helpful to some, I am very glad for your work Solipsis, hopefully it will help out many as this stuff has potential for interesting times but also problematic times as well.

I would say it is best kept as a weekend only thing and I am hesitant to recommend dosing 2 weekends in a row as I think it lingers around.
 
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Oh and the 'amnesia' on this, yeah that tends to manifest with me during re-doses over multiple days and it isn't much of a black out so much as a 'phade' out. Example, mild memory loss of task being completed and confusion regarding completion of said task. IME I just forget what I recently did or didn't do, no black outs just sort of 'did I do that' 'when did I do that?' kind of things. Kinda like nodding out and coming back, not exactly like nodding or dreaming but just that state where you aren't sure on the details of things. This phaded aspect can really hamper interpersonal relationships if you are not able to keep your mind on track, nothing bad has happened to me because of it but I can smell the potential for a bad situation to happen where I dose and have to do things that require more brain-power than my phaded ass can utilize.

Thats about all the suggestions and comments I have for now. I wouldn't advise in combos until you are damn sure you can handle this stuff by itself and even then I would say most are better off not playing around with any. I won't speak on anything being 'safe' to combine as it is all dose dependent and subjective and I think that more harm than good would come out of trying to combine this with numerous potential things.
 
Edited the OP, thanks for the contribution.
I know black-out type fading from GABAergics / downers, whiteout type fading from 5-MeO-DMT type psychedelics, and a more grey/static like dissolution from dissociatives but also in another way pregabalin. I guess MXP's amnesia sounds gradual in a way to me as far as self-consciousness goes. Seems like I know that from when I tried diphenidine, it's eerie to me, I'd much rather have pregabalin for getting blurry although its pretty different. But gradual fade to greyness full of static, yeah must be having your brain activity's integrity to code meaningful information collapse into noise.
 
Edited the OP, thanks for the contribution.
I know black-out type fading from GABAergics / downers, whiteout type fading from 5-MeO-DMT type psychedelics, and a more grey/static like dissolution from dissociatives but also in another way pregabalin. I guess MXP's amnesia sounds gradual in a way to me as far as self-consciousness goes. Seems like I know that from when I tried diphenidine, it's eerie to me, I'd much rather have pregabalin for getting blurry although its pretty different. But gradual fade to greyness full of static, yeah must be having your brain activity's integrity to code meaningful information collapse into noise.

Its nothing very much like the GABAergics/downers amnesia to me although it isn't too dissimilar from a psychedelic 'whiteout' in parts of it. The entire amnesia experience that goes with MXP is most similar to methoxetamine/ketamine 'holing' mixed with a dreamlike and nod-like state. The way I can best describe it is like coming out of a methoxetamine hole although that doesn't even do justice to what happens. I keep saying 'phade' because that is what says it the best for me. You phade out slowly like a nod coupled with going to sleep so that you are in a nod/dreamlike state and then you get a bit of dissociative confusion and euphoria where your mind drifts away for a bit. This can continue for a while or it can be short but it varies to me in both duration and intensity. Sometimes it will be long and very pleasant without amnesia just a very content headspace. Other times it goes more along the lines of nodding into a hole and then you are put in the phaded state and when you come out to a more sober headspace, the intoxication from being in that state and coming back out only slightly can cause confusion as I have mentioned previously.

I don't entirely experience the 'gradual fade to greyness full of static' as you have mentioned but you are very very close in understanding my personal experiences with the 'phade'. With MXP there is a different form of dissociation that I have not experienced before, I wish there could be better terminology used to describe such things but feelings are often hard to describe and definitions are often too vague.

To be dissociated off of methoxetamine is similar to ketamine although both are very different they have many similar feelings. MXE has a more manic/ dopaminergic dissociation to it is very different from ketamine which will glue you down and send you out of your body. MXP walks a fine line between a nod and a dream with its dissociation and I only see a couple similarities to MXE and virtually none with ketamine. For those who have taken SSRI's and felt detached/dissociated, MXP also has a different feeling than that. Hopefully I am not just rambling about this hard to define feeling and someone can get a better understanding out of it.

Another thing to add, MXP can give one a very mild case of 'robo-walking' that is experience by myself on MXE to higher degree and also on DXM to a MUCH MUCH higher degree. MXP has about 1/3 the 'robo-ness'/'wonkiness' that MXE has in my experience although I have not pushed very high dosages with it yet as doses under 200 mg do quite a bit to me. Depth perception is not impaired as badly as with other dissociatives, rather it is more-so like a dreamy psychedelic fuzz/buzz state. Depth perception on 100-150 mg is 75-80% or higher at times compared to 100% normal sober depth perception although things may appear fuzzier and maybe slightly farther away than they really are. It is nothing like other compounds where 4 feet becomes very similar to infinity or where you find yourself unable to judge distances well and are bumping into walls.

That is all I have to add for now, if other comments are added maybe a better effects profile can be built, I am surprised that the past posters who were very intrigued by this substance have stopped posting. I hope that nothing negative has came their way due to dosing issues or some other mishap. Time will tell how this continues to be reviewed by others. I am a bit surprised that there aren't reports coming out of the woodwork for this but I am happy also because I know this has potential to send someone to a state that they do not benefit from.
 
People have been saying it can take up to 8 hours to reach full effect so I'd wait longer than 5-6 hours in for a redose. Not that I've done methoxphenidine.
 
thinking of retrying this thursday just wondering after such a mind blowing time on 2g of mxe am i going to be disappointed or just go into it with a fresh mind and forget any idea of it been anything like mxe ?
 
cheers ive had before but that was when i was how to put a different person got personality disorder so was just thinking it could of been one of the reason as to why but i think il give it another go any one know when mxm the new mxe is coming out ?
 
If you use it for escapism, possibly. However tolerance rises really fast ime, so you can't really abuse it for longer periods of time.

And yeah, if you expect this to be legal MXE, you'll be disappointed. Look at the structure, not the name ;)
 
right one week on after consuming 1g in 24 hours


still have a tingling sensation like a vibration thru my body
my left eye is now having bad double vision

either the batch was tainted or mxp could be very bad for you.
Yup I had the same type of parasthesia off both diphenidine and methyoxy-diphenidine!! It passed after a couple of weeks. I also experienced the symptoms a few times for a couple of days after ingesting these drugs, but only once did it last for weeks. I actually started a thread about it I think. Never had lasting double vision from NMDA antagonists. You should definitely see a neurologist about that, especially if it isn't getting any better day by day!

Here is the THREAD, please reply to it so this is brought to other people's attention. These things quickly get lost in the 'big and dandies' and I think it deserves it's own thread.
 
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1g of this in 24 hours is a VERY high dose (very very high)... I do suspect this substance isn't good for you, but had you kept your dosages reasonable you would probably be fine now. Either way you'll be fine I think, just give it some time and stop taking massive quantities of almost entirely unresearched substances.
 
1g of this in 24 hours is a VERY high dose (very very high)... I do suspect this substance isn't good for you, but had you kept your dosages reasonable you would probably be fine now. Either way you'll be fine I think, just give it some time and stop taking massive quantities of almost entirely unresearched substances.
Needless to say I agree that 1g is a lot, but simply planning to moderate his intake next time will not cut it in my experience. I have sworn to myself I wouldn't redose, put up notes onto my (10kg) scale after putting it as far out of my reach as possible. There are a few drugs which compell me to redose, but I've honestly never experienced anything like this. IV cocaine is straight up reinforcing, but it's different with this substance. It's as if the devil in me took over and compelled me to do the worst thing I could possibly do. Often times I would dose much higher than my initial dose even before I reached the peak to find myself in a complete stupor with no recollection of the experience.

My advice would be to set a fixed dosage before you plan to take either of these two dissociatives and then stash the rest in another place, e.g. at a friend's house.


That being said, I have experienced the tingling even after taking moderate dosages. My lips will often turn numb for a few minutes even weeks afterwards. These symptoms have completely disappeared since I stopped using diphenidine and 2-methoxy-diphenidine. I also went on a ketamine binge of sorts recently, during which I IV'ed 13g within a month and haven't experienced anything similar. Neither has this happened during the time I was an avid PCP user (close to 4 months of daily usage).
 
That being said, I have experienced the tingling even after taking moderate dosages. My lips will often turn numb for a few minutes even weeks afterwards. These symptoms have completely disappeared since I stopped using diphenidine and 2-methoxy-diphenidine. I also went on a ketamine binge of sorts recently, during which I IV'ed 13g within a month and haven't experienced anything similar. Neither has this happened during the time I was an avid PCP user (close to 4 months of daily usage).
Have you stopped taking diphenidine now then man? Just curious cos I know you were a strong advocate for it when it first became available and made some insightful posts about it, so would be interested to know why you decided to give it up, have been strongly considering doing the same recently.
 
Hey crOOk glad to see you again :)

MXP turned out to be fun for me, moderate doses vaped in a glass pipe as usual. Not as fun as diphenidine but also probably not as dangerous. Will have to see though.
I also went on a small K binge before getting my hands on Methoxphenidine hehe so my tolerance might be too high for me to fully appreciate it.
 
I have read quite a few more trainwreck reports about MXP than diphenidine. Also there was a report of a guy who was all fucked up on MXP murdering his mom, with associated news article posted. Having never tried either, my impression is that you need to be even more careful with this one than diphenidine.
 
I have read quite a few more trainwreck reports about MXP than diphenidine. Also there was a report of a guy who was all fucked up on MXP murdering his mom, with associated news article posted. Having never tried either, my impression is that you need to be even more careful with this one than diphenidine.
For serious?!? Links petty please!
 
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