Interesting to see someone else has experienced this. After caning too much acid when I was about 18 I experienced exactly what you describe above. I even went to the doctor, convinced I was suffering some sort of depression. This was about 20 years ago though and they didn't dish out antidepressants like they do nowadays so didn't get given anything to help with it. It then took about a year of staying off all drugs completely for me to get my "normal" head back on.
I've not had acid since, although have tried and enjoyed a wide selection of other substances.
Recently I've been wanting to give DMT a bash, but if there's a danger that it could bring these type of negative post-trip feelings back then I don't think I'll bother. By the way, I wasn't someone that ever really suffered from bad trips. At the time they were all great fun.