^ I've been reading a lot about
gut flora recently, and their importance on the digestive system / liver. (They do so many other things too, it's crazy.) Apparently psychs like mushrooms can cause some dysbiosis in the small intestine. I wondered why when I took a strong probiotic recently that my sleep improved, and it's because most of our serotonin originates in the gut, some of those flora facilitate the tryptophan ---> serotonin process, which of course relates to endogenous melatonin. Liver function is also part of what the flora do.
DMT is too short acting to matter. Mushrooms actually have a cleansing effect on the lymphatic system, but if you're a slow metabolizer (i.e. you stay high for way longer than other people), then I'd take less if you're concerned about toxicity / nervous effects. The only one on that list that is "stimulant" enough to
maybe affect the heart is the 2c group of psychs, and only because they are sympathomimmetic and not true stimulants.