^ Please let's keep on topic and not disappear off into further discussion of whether or not medication is good or bad. You're welcome to discuss whether or not people should self-medicate with MXE (which is a
HUGE no in my opinion, particularly now that we've proven this has some SERT affinity, this is likely going to worsen any depression/anxiety/related problems in the long run with regular use)
Morkin, a tip, you can use the "Search Thread" function near the top of the thread
I'll answer anyway though. What kind of intensity are you looking for?
~15-20mg orally is a nice light dose that gives a pleasant mood boost, some stimulation, and maybe the tiniest hints of dissociation, but nothing much. One lovely thing about this dose range is you'll usually appear sober.
~30-35mg orally starts to get quite dissociating but is still strongly grounded in reality and quite lucid. It might become apparent to people that you're high at this range.
Once you get to 45-50mg+ you're already quite close to "hole" territory and the experiences can be very strongly dissociating at this stage, I'd aim to be somewhere safe where you don't have to interact with anyone you don't want to know is high immediately if you're taking a dose in this range.
If you already have significant tolerance from past dissociative experience you might want to push the doses higher, but I'd recommend starting off low and working your way up anyway - this is quite different from Ketamine and DXM, though they have similarities, and you might not prefer the same level you liked with those substances with this. For example, Ketamine I take to hole and pretty much nothing else, but MXE I'll mostly take at medium doses so I can become more absorbed by a game or films/tv, since the stimulation for me feels a little too dirty and weird at hole doses to make this range preferable.