Hi guys, just wanted to give quick impressions of a couple of synthetic cannabinoids that I've been researching recently; 1g blend of MAM-2201 and 3.5g of UR-144. I obtained both from the same trusted (sort of lol) vendor that I've been using more or less exclusively this last couple of years. These came in unbranded bags in a heat sealed foil pack with a sticker denoting their chemical structure and a CAS reference. Neither have any odour or flavouring, just a vague floor sweepings plant material smell, almost tea-like.
My background in brief; 20 odd years of general recreational drug use, primarily pot, though I take long layoffs between extended periods of use, sometimes months. I'm average build and because I've never been a fan of legal herbal highs I've literally no established tolerance for any CB2 agonist.
Straight to the chase, ROI is plain old pipe and gauze and I'm into the MAM-2201 first, I'm intrigued to find out if it's as scary as it's big brother AM-2201 is supposed to be. Cautious first hit is barely more than a few little particles. After 20 minutes I get very vague tendrils of high so decide to load a proper pinch into the bowl, about the same as I would strong weed. It burns very rapidly to nothing and I hold it in for a good 15 seconds. Onset is megarapid, probably 20 seconds at most. Lots of big, big head buzz and sense of blood pressure building, I can sense my heartbeat is elevated too, but I feel far from uncomfortable, just a little taken aback at just how hard and fast this has hit me. Very pleasant, if a little on the bright and jagged side. This buzz lasts for a good 25 or 30 minutes before receding somewhat. I wasn't couch-locked in the slightest throughout, and much like many of the Dutch haze strains, the more I move about and do things that distract me from it, the better I feel about it's effects. That's worth noting and it's an old trick learned from many past 'Dam trips - keep moving, keep finding things of interest to look at, keep the interaction going and all is generally well.
Some 20 minutes later and I'm onto a small pinch of UR-144. And I'm really surprised by how markedly different it feels against the background of MAM-2201 - that presumably bodes well for mixing the two to useful effect? Don't know. This is much more manageable though, again very Sativa-like, but much less jagged and bright, softer....perhaps the amount used in the blend is less, but after re-dosing some 30 minutes later I'm still of the mind that of the two, UR-144 seems the least likely to bite your face off.
The remainder of one day/evening is spent predominatly re-dosing UR-144 every hour or two, interspersed with some turbo nutter MAM-2201 here and there to get the pulse racing and put some slightly weird spin on the overall experience. I guess all in I got through about half a gram of material during my research. All went very well, very predictably actually.....until I had one last bowl of MAM-2201, more than I should have for sure. Unlike a big Thai Stick binge, this stuff seems a weird combination of rapid tolerance inducing, but also cumulative? Can't explain how else I was sent spinning into the scary tinnitus fear zone right at the end of the night. But that's where MAM-2201 took me. It wasn't monstrously hard to deal with, long experience has taught me what to do under those circumstances - hydrate, force my head space into a pleasant place and just dwell there until sleep comes.
A final word on all of this. I very much like the Sativa buzz. I was a massive fan of White Widow because it always felt like the best of all worlds; immensely potent but with the added payoff of motivating one to go out and do things. Perhaps it's my taste for the speedier weed experience that gave me some affinity for these substances, dunno. Perhaps I've been lucky these last few days. But I've really, really enjoyed both of these chems. They seem so much less...empty than most other synthetics I've tried in the past. In the case of MAM-2201, it's a very powerful thing, it will positively fuck you up if you don't show it some serious respect, I certainly came close to having something close to a very edgy time on it once or twice. BUT...it's a very nice buzz, very cerebral, very thought energizing. In fact, MAM-2201 seems to me like a doing small doses of MXE while smoking a lot of some decent skunk. And getting up the next day, both seem to have a similar afterglow to good old fashioned MJ, but with much less of a hangover, or so I've found.
I can definitely see two problems with these chems besides us having no idea what the long term effects are; high addiction potential (immediate fat and speedy buzz, fast tolerance and dizzyingly rapid diminishing returns), and anyone with a lack of longer term experience of handling tryptamines is possibly going to find the weird speedy, slightly head fucky world MAM-2201 can plunge you into at the very least highly disconcerting, possibly overwhelmingly, hospital visity panic-inducing. I loved both of these chems, and I'd go as far as to say if I were so inclined, and if I were not so concerned about long-term exposure to an untested substances like these, I'd consider both a serious substitute benched alternative to those wonderful Sativa dominant strains that seem so rare to appear these days.
My background in brief; 20 odd years of general recreational drug use, primarily pot, though I take long layoffs between extended periods of use, sometimes months. I'm average build and because I've never been a fan of legal herbal highs I've literally no established tolerance for any CB2 agonist.
Straight to the chase, ROI is plain old pipe and gauze and I'm into the MAM-2201 first, I'm intrigued to find out if it's as scary as it's big brother AM-2201 is supposed to be. Cautious first hit is barely more than a few little particles. After 20 minutes I get very vague tendrils of high so decide to load a proper pinch into the bowl, about the same as I would strong weed. It burns very rapidly to nothing and I hold it in for a good 15 seconds. Onset is megarapid, probably 20 seconds at most. Lots of big, big head buzz and sense of blood pressure building, I can sense my heartbeat is elevated too, but I feel far from uncomfortable, just a little taken aback at just how hard and fast this has hit me. Very pleasant, if a little on the bright and jagged side. This buzz lasts for a good 25 or 30 minutes before receding somewhat. I wasn't couch-locked in the slightest throughout, and much like many of the Dutch haze strains, the more I move about and do things that distract me from it, the better I feel about it's effects. That's worth noting and it's an old trick learned from many past 'Dam trips - keep moving, keep finding things of interest to look at, keep the interaction going and all is generally well.
Some 20 minutes later and I'm onto a small pinch of UR-144. And I'm really surprised by how markedly different it feels against the background of MAM-2201 - that presumably bodes well for mixing the two to useful effect? Don't know. This is much more manageable though, again very Sativa-like, but much less jagged and bright, softer....perhaps the amount used in the blend is less, but after re-dosing some 30 minutes later I'm still of the mind that of the two, UR-144 seems the least likely to bite your face off.
The remainder of one day/evening is spent predominatly re-dosing UR-144 every hour or two, interspersed with some turbo nutter MAM-2201 here and there to get the pulse racing and put some slightly weird spin on the overall experience. I guess all in I got through about half a gram of material during my research. All went very well, very predictably actually.....until I had one last bowl of MAM-2201, more than I should have for sure. Unlike a big Thai Stick binge, this stuff seems a weird combination of rapid tolerance inducing, but also cumulative? Can't explain how else I was sent spinning into the scary tinnitus fear zone right at the end of the night. But that's where MAM-2201 took me. It wasn't monstrously hard to deal with, long experience has taught me what to do under those circumstances - hydrate, force my head space into a pleasant place and just dwell there until sleep comes.
A final word on all of this. I very much like the Sativa buzz. I was a massive fan of White Widow because it always felt like the best of all worlds; immensely potent but with the added payoff of motivating one to go out and do things. Perhaps it's my taste for the speedier weed experience that gave me some affinity for these substances, dunno. Perhaps I've been lucky these last few days. But I've really, really enjoyed both of these chems. They seem so much less...empty than most other synthetics I've tried in the past. In the case of MAM-2201, it's a very powerful thing, it will positively fuck you up if you don't show it some serious respect, I certainly came close to having something close to a very edgy time on it once or twice. BUT...it's a very nice buzz, very cerebral, very thought energizing. In fact, MAM-2201 seems to me like a doing small doses of MXE while smoking a lot of some decent skunk. And getting up the next day, both seem to have a similar afterglow to good old fashioned MJ, but with much less of a hangover, or so I've found.
I can definitely see two problems with these chems besides us having no idea what the long term effects are; high addiction potential (immediate fat and speedy buzz, fast tolerance and dizzyingly rapid diminishing returns), and anyone with a lack of longer term experience of handling tryptamines is possibly going to find the weird speedy, slightly head fucky world MAM-2201 can plunge you into at the very least highly disconcerting, possibly overwhelmingly, hospital visity panic-inducing. I loved both of these chems, and I'd go as far as to say if I were so inclined, and if I were not so concerned about long-term exposure to an untested substances like these, I'd consider both a serious substitute benched alternative to those wonderful Sativa dominant strains that seem so rare to appear these days.
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