Limpet_Chicken
Bluelighter
I know 2-alkyl BENZOfurans are often/usually hepatotoxins, does this apply to furans also?
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N&PD Moderators: Skorpio
I Like to Draw Pictures of Random Molecules
- Thread starter nuke
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killermunchies
Bluelighter
- Joined
- Jul 9, 2010
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- 552
I was just joking about the MSpaint
I used BKchem to draw those.
Upon further review, it seems the two lone pairs on oxygen are necessary (at least the oxygen in the 4th position) to H-bond with the receptor.
Nitrogen, with its single lone pair + hydrogen would be vastly inferior in this regard. And probably toxic.
There was a thread on here a while back about using "Benzoxazole" (one O and one N) that proved promising...
I wonder if the resonance within the 5-membered ring helps or hurts its potency...
6-APB only has the oxygen across from the 3 position and that seems to be active, and 5-IT has no oxygens at all. 5-IT seems to be pretty rough, but it is active.
sekio
Bluelight Crew
WHY?
The Texas carbons/nitrogens (hypervalent- no carbon has 5 bonds!) are esp. distressing, and the strained double-bonds don't make this molecule look happy either. Nor the ketene moiteys.
This whole thing would just as soon blow up as exist
pharmakos
Bluelighter
reminds me of froganamine =p
That nitrogen doesn't only have more bonds than electrons in its valence shell, it has more bonds than electrons in all its shells! But I have a feeling Albion knew that his structure might not be the easiest thing to knock up in the lab
I'm sure it's fine, no chemists in ADD
Albion
Bluelight Crew
- Joined
- Mar 7, 2010
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- 11,070
That nitrogen doesn't only have more bonds than electrons in its valence shell, it has more bonds than electrons in all its shells! But I have a feeling Albion knew that his structure might not be the easiest thing to knock up in the lab
I'm sure it's fine, no chemists in ADD
If nobody has conceived of that specific molecule before, do I get dibs on naming it?
amanitadine
Bluelighter
No problems there I am sure! I think most folk here would quickly distance themselves from conceiving such a beast!Last edited:
amanitadine
Bluelighter
Well come on with the name then! I think you may have dethroned the reigning batshit crazy chem-wanks in the house . . .( no names mentioned. . . .)klfiend
Bluelighter
If 2c-e had a baby with mescaline
2-FMA was pretty sweet, lets get some ring fluorinated phenmetrazine in this bitch
or is this one gonna be the winner?
Think I have heard this was made and disappointing
the phenmetrazine analog to 4-mmc and 4-mma
wonder what happens if we extend the alpha chain?
one more extension for good measure (or to get past bans)
Last edited:If 2C-E had a baby with mescaline, that ethyl group would be in the para position and the methoxyls at both metas. And if we're going for structural isomers of 2C-E, psi-2C-E would be where I would look (although I imagine the duration might be on the high side).
Because everyone knows that 3,4-methylenedioxy is PURE WIN in any compound.
The bases are pretty much covered, ketamine/tiletamine etc at the 2, methoxetamine and the 3-MeO-PCxs at the 3, 4-MeO-PCP apparently demonstrating that the para is not where the action is.
Thioether is a bit out there, but I would actually like to see a ketone and a piperidine ring on the same one, that should be nice.
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pharmakos
Bluelighter
the 2-Fluoro analogue of ketamine was made by a university in the middle east (University of Iran maybe? i forget). i feel like the 2-Fluoro is going to be the winner out of all the 2-Halos. who knows tho.- Status
