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  • EADD Moderators: Shambles

Ketamine: A cure to depression? (Texas studies)

Not the case for me and many of my friends who found it to cause depression (almost like a comedown) after.



I don't really see there being any problem with side effects from a single dose once every week or two brimz. It takes a fair bit of binging (regularly) to even get the hot feeling piss, I've only ever had a moderate dose of the cramps but it took a week of stupid dosing to bring them on.

I think most of the analogues they've come up with so far (bar methoxetamine) are thought to be worse on the bladder (2-MeO etc), not to mention less tested. Ketamine we know a conciderable amount about what the likely outcome is.

Yeah but before one of the Glaxos of the world will put out a drug they will try and make it water tight legally . They can't afford any repeat of Seroxat . Many drugs get so far but not past the lawyers .
 
Not the case for me and many of my friends who found it to cause depression (almost like a comedown) after.

after what? A recreational dose or an anti-depressant dose?
Most anti-depressants will cause accute depression post-use if you take a dose that is many times the prescribed dose for depression, especially when not taken with any regularity.
Personally, when using methoxetamine as a anti-depressant it's a 3 times a day, 7 days a week thing.
 
I never got depression after MXE, only the opposite. Could feel sad during but never after. I have to say I feel pretty fucking chirpy after going daft with 3-MeO-PCP last week too!
 
after what? A recreational dose or an anti-depressant dose?
Most anti-depressants will cause accute depression post-use if you take a dose that is many times the prescribed dose for depression, especially when not taken with any regularity.
Personally, when using methoxetamine as a anti-depressant it's a 3 times a day, 7 days a week thing.

I've done it both ways. Overdoing it to the point of 3-500mg in a night. Dosing just 10mg twice a day all week.

The only time I had much sucess was after I'd already binged on ketamine for a week and happened to still have best part of a gram of MXE, 20-30mg a day kept me upbeat and saved me having to order more K.

There is no doubt which one I'd rather have.
 
From November to the beginning of February I had a really bad episode of depression and was experiencing the worst case of memory loss I've ever hadd in my life. Thankfully I decided to reorder some MXE (Never tried Ketamine) after not using for about August time.

After the first dose it made me snap out of it and my memory problems stopped and also regained 2stone I'd lost since Nov'.

I just wish it had never been bannned. :(
 
I've done K before infrequently, and it was great - no complaints about it. My only concern is that I heard if you do it too often for too long, it will do something to your receptors to prevent you from getting LSD visuals. Not sure if this is true or not, but that idea freaks me out!
 
I heard if you do it too often for too long, it will do something to your receptors to prevent you from getting LSD visuals. Not sure if this is true or not, but that idea freaks me out!

Most certainly not true!
K works on NMDA. LSD works on 5HT2a/b/c etc.

On the subject tho... K + LSD is a lovely combo. %)
 
I wish i'd experimented with more lower doses of mxe,between 10 and 15 mgs.The trippy side kind of put me off it,felt benign but weird and went on forever. Never done ket,but it seems more positive than mex.Would be nice to feel more content,maybe even 'happy' rather than AD's just taking the edge off.
 
I wish i'd experimented with more lower doses of mxe,between 10 and 15 mgs.The trippy side kind of put me off it,felt benign but weird and went on forever. Never done ket,but it seems more positive than mex.Would be nice to feel more content,maybe even 'happy' rather than AD's just taking the edge off.

I only ever sniffed a max' of 50mg. Once redosed too early (So had 100mg) and went into a hole). Didn't like it.

When it came to IM'ing (When I was running out post-ban) and had about 250mg left, I was using 20mg doses.

I don't like tripping to be honest, just the increase in energy, euphoria and anti-depressant effect! :)

Also took around 150mg of Methadone and then took my normal dose of 50mg MXE abit later and that put me in a hole. I think it might have been because Methadone also works on the NMDA receptors. Anyway I ended up after 20mins fine walking and talking (Don't remember much of the night) but it'd scared my mates too much by then and took me to hospital even though I was up and about talking.

I only remember 1 bit whilst tripping in the hospital and that was when I woke up had loads of tubes stuck to me, took'em off and as I was in isolation got off the bed and opened the door. I'm guessing it was a male nurse cause he immediately ran towards and said "It's OK Gary get back on the bed!" and I remember saying "Are you a robot?!" (I was still tripping and nodding hard and had the blurred vision off of MXE) and he obviously replied "No, I'm not a robot." and helped me on the bed and said lay down. So I went back to sleep.

Thankfully they didn't give me naloxone for the meth' (I'm guessing my mates either forgot or didn't know I'd taken it, I'm thinking one forgot.) otherwise I'd of potentially died as I have a condition that if I go into withdrawal from opiates/opioids will kill me! :\

When I woke up in the morning and was sober enough to go home (About 10am) I had about 5 doc's and nurse's asking me what I'd taken. I told them and they we were around a computer on google straight away. I told them it was related to ketamine and as soon as they punched it in on google the site I got it from came up. :D This was late early 2011.

My specialist a few months later who I see about my condition said to me "Oh I heard you were on ketamine and came in here a few weeks ago!", she said it with a smile. I told her what it was. She knows I still use 'stuff' and I even went through along list of drugs with her about if I have to increase/decrease my dose when taking them, as I'd been increasing my dose on speed and ephedrine (Stimulants increase the drug/hormone) I'm and she told me not too. Anyway I found out I need to not increase it on anyway, thank fuck. :)
 
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Ket definitely has a positive effect on me in the days after and I regularly suffer from depression and anxiety. It's funny though, I went through a period of using it LOADS around 2003 but now I just find I really want it every 2-3 months. Once I have a good few holes I'm usually fine for a good while and don't immediately think, "right, where's the next lot coming from?".

Good ol' K.
 
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