We have discussed the T-shirt process thoroughly and in the next few days I will be doing a bit of research and calculations. Its really important which I havnt seen anyone mention is that one needs to use WARM water to dissolve the pills then GRADUALLY cooling the solution down until it is very cold.
Ibuprofen is a white powder with a melting point of 74-77° C and is very slightly soluble in water (< 1 mg/mL) and readily soluble in most organic solvents. Now I use 3ml for every pill usually which is roughly about 90ml of water. The solubility is 1mg for every ml of water making the maximum amount of ibuprofen in the water 90mg which will be deducted from the end result once I have established the exact weight of the filtered ibuprofen and other inactives such a fillers and starch etc etc.
Filtration using a very fine tight knit/woven T-shirt
Completion of the filtration leaving behind Ibuprofen and other inactives
In the beginning before the filtration it contained 6000mg Ibuprofen - 90mg (that dissolved) = 5910mg. A panafen plus pill weighs 667mg. So 667mg - 12.8mg (codeine) - 200mg (ibuprofen) = 454.2mg of other inactives x 30 pills =
13 626mg + ibuprofen= 19626mg.Now bear in mind that ibuprofen very very slightly soluble in water so basically no issues there like I mentioned earlier the solution contains roughly 90mg of ibuprofen. So after keeping the filtered contents I will dry it out and see exactly how much the weight will be. Another thing to note I prob lost about a gram give or take due to it sticking to the filter and etc. Lets see how close the figure gets to roughly 18 000mg.
Another thing to note, Im not exactly sure how soluble all the other ingredients are but I imagine a fair few of them are pretty water soluble too. Which would also bring down the 18 000mg target. When I have a bit more spare time I will conduct another experiment where I will evaporate the solution and see how much Ibuprofen + inactives are left, and can incorporate those figures into teh calculations as well.
Lets just say I evaporated my solution (its a bit cloudy but not because of the ibuprofen itself after filtration) id imagine I wouldnt end up with more than half gram of solids (which I have tried long time ago) and lets just assume that all of it was ibuprofen thats about 2.5 pills. There are ibuprofen pills out there that contain 800mg each and 2.5 pills of P+ would be the appx recommended dosage.
Its good to see you being very cautious however I'm a very scientific guy and prefer research done on things. We have discussed the T-shirt process thoroughly and in the next few days I will be doing a bit of research and calculations. Its really important which I havnt seen anyone mention is that one needs to use WARM water to dissolve the pills then GRADUALLY cooling the solution down until it is very cold.
Ibuprofen is a white powder with a melting point of 74-77° C and is very slightly soluble in water (< 1 mg/mL) and readily soluble in most organic solvents. Now I use 3ml for every pill usually which is roughly about 90ml of water. The solubility is 1mg for every ml of water making the maximum amount of ibuprofen in the water 90mg which will be deducted from the end result once I have established the exact weight of the filtered ibuprofen and other inactives such a fillers and starch etc etc.
Filtration using a very fine tight knit/woven T-shirt
Completion of the filtration leaving behind Ibuprofen and other inactives
In the beginning before the filtration it contained 6000mg Ibuprofen - 90mg (that dissolved) = 5910mg. A panafen plus pill weighs 667mg. So 667mg - 12.8mg (codeine) - 200mg (ibuprofen) = 454.2mg of other inactives x 30 pills =
13 626mg + ibuprofen= 19626mg.Now bear in mind that ibuprofen very very slightly soluble in water so basically no issues there like I mentioned earlier the solution contains roughly 90mg of ibuprofen. So after keeping the filtered contents I will dry it out and see exactly how much the weight will be.
Another thing to note, Im not exactly sure how soluble all the other ingredients are but I imagine a fair few of them are pretty water soluble too. Which would also bring down the target. When I have a bit more spare time I will conduct another experiment where I will evaporate the solution and see how much Ibuprofen + inactives are left, and can incorporate those figures into teh calculations as well.
Lets just say I evaporated my solution (its a bit cloudy but not because of the ibuprofen itself after filtration) id imagine I wouldnt end up with more than half gram of solids (which I have tried long time ago) and lets just assume that all of it was ibuprofen thats about 2.5 pills. There are ibuprofen pills out there that contain 800mg each and 2.5 pills of P+ would be the appx recommended dosage.
Outcome:
30 pills x 667mg each = 20 010mg. Now 20 010mg - 30 pills x 12.8mg = 384mg. We subtract the codeine from the pill mass, 20 010mg - 384mg (codeine) - 90mg (ibuprofen that was water soluble) = 19 532mg.
After the pill mass was dried thoroughly this was the outcome
19 300mg of junk has been removed. 19 532mg - 19 300 = 232mg (Now this could be either 100% ibuprofen, codeine (I really hope not but I suppose its better loosing that then ibuprofen into the solution) or fillers and inactives. Either way 232mg will not cause serious harm. These calculations are not 100% accurate as there are a few other factors involved. Method was done with a T-Shirt.
Time to drink my CWE, cheers
Done
