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Any simple cures or aids to help get rid of "de-personalization".

pbuilder

pbuilder

Bluelighter
Joined
Oct 24, 2011
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Basically, i popped an m pill for my first time on saturday, while already quite drunk and under the influence of other drugs, including oxy.

So a), this is already a bad idea, mdma should be taken sober.

b), i got the pill from someone i barely know, so it likely had some sort of psych in it, or wasn't even mdma at all, cause i was drunk testing it was the last thing on my mind.(dont need to hear how stupid this was)

and c), i read online that apparently oxy and mdma have a synergy that gives it a dissassociation/weird psychness to it.

I'm very inexperienced with psychs or dissassociates, other than diphenhidramine and dxm, both only in low doses (never above 200mg).

Even those doses had me feeling weird and out of control, so i generally stay away from psychs. Same thing with weed, i hate feeling like im in a dream or something, like im just watching myself do sh*t.

Anyways, since that night I've felt oddly disassociacted with my life, like im just watching myself do shit and i dont know, like im kinda forgetful cause it almost feels like a dream, everythings sorta hazy...

Basically, what are some things that can help with this? Maybe exercize, certain vitamins, i don't know that's why im asking for all your opinions.

Thanks!

edit: and to just clear things up, i believe their was some sort of psychedlic involved in the pill thats why i posted here, and de-personalization and dissassocation are common side effects from psychedlics so i figured you guys would have the most knowledge.
 
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^ I STRONGLY advise against ingesting poison, or 5-htp as some call it. It is cardiotoxic and I can show you the research if you don't want to do the googling yourself.

Aniracetam and similar nootropics can be helpful in reclaiming your sanity, along with a healthy diet and lots of exercise.
 
^ It seems that we are talking about what the human body can handle, and it is quite a lot. I know someone who has been on 360mg of oxycodone daily for 25 years, now THAT is some hardcore shit.

Back on topic though, here's the research.


"5-HTP can cause hypertension by increasing plasma renin activity, when not co-administered with a peripheral aromatic L-amino acid decarboxylase inhibitor, such as carbidopa or benserazide"

"Some clinicians suggest that 5-HTP be administered with a peripheral decarboxylase inhibitor (such as carbidopa) to prevent elevated serotonin levels in the bloodstream (and the subsequent side effects)."

"Safety, Side Effects and Warnings:

5-HTP should not be used by those hypersensitive to any component of a 5-HTP-containing product. It is also contraindicated in people with carcinoid tumors, and during or within 2 weeks after discontinuation of an MAOI.

Large doses of 5-HTP can trigger excess of serotonin formation in tissues other than the target organ and cause significant adverse effects. It should not be used concurrently with any antidepressant, including SSRIS, tricyclics, or MAOIs. Concurrent 5-HTP use with an antidepressant may increase the risk of adverse reactions. 5-HTP should not be used by those with ischemic heart disease, coronary artery spasm, uncontrolled hypertension and any other significant cardiovascular disease."

"At the very best, people who take B-vitamins with 5-HTP, or
who take 5-HTP products with B6, waste their money. All this
would be merely humorous (caveat emptor) were it not for some
other facts. At worst, ignorant people fooling with 5-HTP
actually risk their health, since serotonin in the peripheral
blood is not benign. Serotonin causes not only harmless flushing
and diarrhea, but people with serotonin secreting tumors (hindgut
carcinoids) also have problems with fibrosis of the endocardium
and valves in their right hearts, which can cause heart failure.
This fibrosis is caused by the serotonin. This effect can also
be seen with dietary intake of only modest amounts of serotonin,
and there has actually been described in the medical literature a
tribe of South Sea islanders with right heart fibrosis as a
result of eating green banana mash (matuki), which poisons them
with its serotonin content. No, I'm not making this up. The
hydroxylation of tryptophan is a rate-limiting step in the
peripheral production of serotonin, and one bypasses it at one's
peril.

How much does it take? Several hundred milligrams of 5-HTP
taken per day, if converted to serotonin, would result in a
urinary excretion of the serotonin metabolite 5-hydroxyindoleac-
etic acid (5-HIAA) of several hundred milligrams also-- an amount
well within the urinary excretion range of the average person
with a serotonin producing carcinoid. Such a dose of 5-HTP
certainly would result in a serotonin blood load comparable to
that of green-banana-diet eating people who have
serotonin-induced heart valve disease. Normally, people do not
excrete breakdown products of more than 10 mg of serotonin
metabolites per day. If you take one capsule per day of 50 mg
5-HTP with 10 mg B6, however, you would be expected to go to at
least 50 mg per day of 5-HIAA in the urine. Less metabolism in
the liver (less B6) would result in less 5-HIAA in the urine. If
you are going to take 5-HTP, therefore, you probably need 5-HIAA
urine monitoring, to figure out just how big a dose of systemic
serotonin you're actually getting (and incidentally, how much
5-HTP you're wasting). See a doctor!

For all the reasons outlined above, I am presenting those
vitamin companies who sell 5-HTP with B6, or who sell it alone
but don't warn their customers about 5-HIAA monitoring or B6
intake, a special award: the Green Banana Award. This honor is
for those supplement-sellers who monkey around with people's
health before consulting with some really good nutrition and
medical specialists to make sure they don't f*&% up and hurt
somebody. Hopefully, companies which receive the Green Banana
Award will contemplate its message, and will thereby change their
behavior in order to avoid some of the less-coveted awards which
otherwise await them in the future: the Civil Damage Award, for
instance, or even the All-Expense-Paid Guest of the Federal
Government Award." -Steven B. Harris, M.D.
 
....I'm no longer sure what we're talking about. I can tell you from personal experience MDMA definitely has an ugly, ugly dark side if you choose to abuse her. I'm simply trying to show you why ingesting 5-htp is a damned horrible idea. I care about peoples' health man, including yours.
 
What will help you? Time. Stay hydrated, drink a lot of water. In a few days you'll start to feel back to normal.
 
You might want to try eating strongly flavored food, surrounding yourself with bright colors, listening to loud music, burning strong-smelling incense, ice packs and a cold shower, vigorous exercise, or other really sensory stimulating activities. Several years ago, I used to have depression with dissociative symptoms, and these things would always really help me.
 
Excerise of course be healthy eat the right food, keep your self occupied and entertained with activities that intrests you.

meditation and yoga helps alot ime, also for some people taking a good break from drugs works.

A good multi vitamin is always good to if your able to take those. Also have seen people go out and find them a girlfriend/ boyfriend to take there minds of there mind.

Take it easy everyone,
 
No drug will ever cure you of depersonalization. If depersonalization is stripping meaning from your world, immerse yourself into it and let meaning flood back in. I've been there, and the healthiest way out is just going out and seeing people, making friends. Go eat some of your favorite food, do something you've never done. Go fucking LIVE man!
 
5-htp is naturally occurring in the body, so how on earth can it be cardio-toxic? Anyway... moving on...

Best way to help with de-personalization is to take a big break from getting altered, 3 months minimum but 6 months is ideal. Focus on nutrition, healthy lifestyle (like appropriate exercise), and reconnecting with the human world. Depersonalization is a product of being severely ungrounded. You need to re-connect with people, worldly activities, the earth, and most importantly yourself. It's hard to tell what you even need when you are so out to lunch.

I know it's hard but a big break from getting altered can do wonders, and is your first step to improvement.
 
Foreigner said:
5-htp is naturally occurring in the body, so how on earth can it be cardio-toxic?
Click to expand...
That's a pretty stupid question. The fact that something occurs naturally in the body doesn't mean administering it orally doesn't have negative effects. It could be toxic in higher amounts than the amount which is naturally occuring in the body for example.

I see the post by cryptix420 already explained this: "Large doses of 5-HTP can trigger excess of serotonin formation in tissues other than the target organ and cause significant adverse effects." That means it might not be toxic in the amounts in which it normally occurs in the body, but higher levels of 5-htp, achieved by taking supplements, can be.
 
Yea, I was going to recommend one of the racetams with choline as well. Maybe low dose Wellbutrin? But honestly, just lay off for a while, and pot makes it 100x worse..get outside and just force yourself to interact. You prob just wanna stay hidden, but this makes it worse, too.
 
B.mans said:
That's a pretty stupid question. The fact that something occurs naturally in the body doesn't mean administering it orally doesn't have negative effects. It could be toxic in higher amounts than the amount which is naturally occuring in the body for example.

I see the post by cryptix420 already explained this: "Large doses of 5-HTP can trigger excess of serotonin formation in tissues other than the target organ and cause significant adverse effects." That means it might not be toxic in the amounts in which it normally occurs in the body, but higher levels of 5-htp, achieved by taking supplements, can be.
Click to expand...

It's serotonin at high doses, not 5-htp, that causes the probem - and this study was done in rats, not humans. I'll spare you the pages of research and give you a nice little laymon summary:

http://en.wikipedia.org/wiki/5-Hydroxytryptophan#Possible_risks_or_side_effects

Also, even if true, it would depend on your pre-existing body condition, how high your dose is, and how long you're taking it. You can't just run around saying "5-HTP CAUSES HEART PROBLEMS OMGZZZ!!!111" because it would be different for every person.
 
Yeah, chill with the anti-5HTP hype. I've been taking it for years, on and off as needed, sometimes for months in a row, and the worst side effect i've gotten is slight stomach upset. It can be really useful for combating fear-based mental patterns.

So can a quick, brisk Salvia trip.
 
I've had depersonalization ever since surgery, on-and-off, common in stresfull times, used to get it when drinking/after drinking.
Best way I found was to relax, and forget about it.
I find I forget about it if I go on the PC, like my brain doesn't need to use the area that it's in when I'm on the PC, so I forget about it.
Drinking lots of water, staying calm and realizing it'll leave when it's ready, don't let it get in your way.

I find it's common for me to get intense depresonalization peaks when in dim lighting, like shitty sports halls.
I often get it when I'm depressed.
There's whole forums out there dedicated to it, check them out.

I've nver thought of taking a nootropic on it, that.. would be interesting to try, I'll try it next time.
Staying off drugs is definitely recommended.
 
RhythmSpring said:
Yeah, chill with the anti-5HTP hype. I've been taking it for years, on and off as needed, sometimes for months in a row, and the worst side effect i've gotten is slight stomach upset. It can be really useful for combating fear-based mental patterns.

So can a quick, brisk Salvia trip.
Click to expand...


anti 5-htp hype? You've got to be joking.

Ever heard the phrase 'knowledge is power'? It's not like I'm selling tryptophan here. I am passionate about peoples' health. If I hadn't personally had negative reactions to 5-htp I would keep my mouth shut about it.

Let me rephrase your post to show you why it's a bit ridiculous

"I've been drinking budweiser for years, on and off as needed, sometimes for months in a row, and the worst side effect I've gotten is slight stomach upset. It can really be useful for alleviating my anxiety."
 
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