• Neuroscience & Pharmacology Discussion Welcome Guest
    Posting Rules Bluelight Rules
    Recent Journal Articles Chemistry Mega-Thread
    FREE Chemistry Databases! Self-Education Guide

  • N&PD Moderators: Skorpio

How toxic is Mephedrone?

dimensiontripping said:
The only proof I have is that I did 1g of mephedrone in a session and 2 days later, when I had sex it was extremely painful post -orgasm. I spent months trying to figure the issue out after being misdiagnosed with prostate infection, chrons disease, and was finally diagnosed with myofascial pain in my pelvic floor and lower abdomen. I was completely healthy young adult male. There is no reason this would have happened normally. it has been 7 months and I have abstained from using mephedrone since then and continue to have this issue but is slowly going away. You want a medical record? I dont have that. do doctors understand mephedrone? no. Do I have personal evidence that this is caused by mephedrone, hell ya. I know you are trying to filter people who are complaining and two issues may be unrelated but I know this are completely related. Mephedrone caused my long-term muscular damage. Simple as that.
Click to expand...

I'm sorry for you. I've heard similar cases with MDMA as well, not muscular problems but liver failures with a relatively low abuse. I guess it's not common but can happen.

Of course your experience is useful, but we can't say mephedrone is gonna hurt everybody even with responsible comsumptions. I mean, I know hundreds of people who did this drug in the past and i haven't noticed any problems with them.

Did you notice any problems with your experiences with less than 0.5-0.6gr?
 
Velvet cacoon said:
I'm sorry for you. I've heard similar cases with MDMA as well, not muscular problems but liver failures with a relatively low abuse. I guess it's not common but can happen.

Of course your experience is useful, but we can't say mephedrone is gonna hurt everybody even with responsible comsumptions. I mean, I know hundreds of people who did this drug in the past and i haven't noticed any problems with them.

Did you notice any problems with your experiences with less than 0.5-0.6gr?
Click to expand...

no, it was once i breached my .5-.6 limit that this occurred and I only did this once. I know I am a special case and cannot speak for everyone at all but i think it is important to bring even unusual side effects to the main discussion. I have no access to it nor do any of my friends and I am grateful for this. The original argument amongst my circle of friends was that since mdma was so impure or actually a mix of RC products resold at super high inflation, that taking known pure RC's was safer than consuming "molly" or "beans" This actually seemed to resonate as being true for a bit, but upon my negative reaction (which I must say none of atleast 20 people I know who took same batch experienced) everyone stopped. I would love to take pure mdma as that was never a problem before there was loss of access. But I now doubt all new amphetamine/cathinone RC's for me personally as it seems my body chemistry and them do not work well together.
 
dimensiontripping said:
no, it was once i breached my .5-.6 limit that this occurred and I only did this once. I know I am a special case and cannot speak for everyone at all but i think it is important to bring even unusual side effects to the main discussion. I have no access to it nor do any of my friends and I am grateful for this. The original argument amongst my circle of friends was that since mdma was so impure or actually a mix of RC products resold at super high inflation, that taking known pure RC's was safer than consuming "molly" or "beans" This actually seemed to resonate as being true for a bit, but upon my negative reaction (which I must say none of atleast 20 people I know who took same batch experienced) everyone stopped. I would love to take pure mdma as that was never a problem before there was loss of access. But I now doubt all new amphetamine/cathinone RC's for me personally as it seems my body chemistry and them do not work well together.
Click to expand...

the whole point of this thread is to highlight the negative reactions people have had from mephedrone. its purpose is being served in an insightful manner
 
ebola? said:
Can someone with more chemistry knowledge than I comment on whether sticking a 3,4-methylene dioxy on a cyclohexane group would even make sense? Given the geometry of cyclohexane, where would the MD even stick out toward? If the drop in potency is analogous to methamp----->mdma, I don't see this compound being viable anyway.

ebola
Click to expand...

I heard speculation that the methylenedioxy ring would quickly be cleaved, yielding certain toxic byproducts I don't recall. Also, I don't think the SARs for benzene containing compounds likely apply to cyclohexanes...
 
The many after affects of mephedrone

I haven't chimed in on this thread in awhile so I think it's time for an update... In 2010 I bought close to a kilo of mephedrone. I did 1-3 grams a day for about 2 months. After the meph got confiscated by the police I got into smoking and IV-ing mdpv.

I had chronic pain previously but now it is much worse. My first 2 clinical diagnoses after meph were fibromyalgia and high blood pressure. I am 27 years old.

Recently I had a yearly blood test and my TSH (thyroid stimulating hormone) was below normal, indicating hyperthyroid. This level was fine at the end of 2010 though.

I am now taking 120mg/day of cymbalta (duloxetine, the maximum), blood pressure meds, tramadol, several grams of neurontin a day, several grams of kratom a day, and still in so much pain at the end of the day in my knees and back that i just want to curl up and die.

Back when I was doing so much meph I had skin peeling on feet, hands, mouth, purple legs/knees, etc.

It was just about the most euphoric drug I have ever done (and I have tried a LOT of drugs in my lifetime). Compared to the meph, MDPV was complete crap, but it is extremely addictive even though the high isn't very good. And the amphetamine psychosis from the mdpv was terrible. Even from meph at 1-3 grams a day everyday for nearly 2 months.

Just an update. Do I wish I had never tried meph? Absolutely not. I do wish I had the will power to have been responsible with it though. No doubt in my mind that is very toxic stuff. I feel like I have vascular damage (vericose veins in legs) and also nerve damage (chronic widespread pain). You gotta pay to play though. The harder you play, the more you pay.

I have since given up stims except for the occasional adderal when visiting a close friend. I haven't touched a needle since August 2010.

Cheers,
-SimStim
 
simstimstar said:
I haven't chimed in on this thread in awhile so I think it's time for an update... In 2010 I bought close to a kilo of mephedrone. I did 1-3 grams a day for about 2 months. After the meph got confiscated by the police I got into smoking and IV-ing mdpv.

I had chronic pain previously but now it is much worse. My first 2 clinical diagnoses after meph were fibromyalgia and high blood pressure. I am 27 years old.

Recently I had a yearly blood test and my TSH (thyroid stimulating hormone) was below normal, indicating hyperthyroid. This level was fine at the end of 2010 though.

I am now taking 120mg/day of cymbalta (duloxetine, the maximum), blood pressure meds, tramadol, several grams of neurontin a day, several grams of kratom a day, and still in so much pain at the end of the day in my knees and back that i just want to curl up and die.

Back when I was doing so much meph I had skin peeling on feet, hands, mouth, purple legs/knees, etc.

It was just about the most euphoric drug I have ever done (and I have tried a LOT of drugs in my lifetime). Compared to the meph, MDPV was complete crap, but it is extremely addictive even though the high isn't very good. And the amphetamine psychosis from the mdpv was terrible. Even from meph at 1-3 grams a day everyday for nearly 2 months.

Just an update. Do I wish I had never tried meph? Absolutely not. I do wish I had the will power to have been responsible with it though. No doubt in my mind that is very toxic stuff. I feel like I have vascular damage (vericose veins in legs) and also nerve damage (chronic widespread pain). You gotta pay to play though. The harder you play, the more you pay.

I have since given up stims except for the occasional adderal when visiting a close friend. I haven't touched a needle since August 2010.

Cheers,
-SimStim
Click to expand...

did you tell your doctor about your abuse? where is your pain located? I have strong abdominal, genital, lower back pain after taking mephedrone in august 2011. I was diagnosed with so many things but I did not tell my doctors that I was taking cathinones/amphetamines (I was taking methylone, adderall as well but not in combination with mephedrone). Eventually, i have gone to see a myofascial therapist and unlike you, I dont think I have nerve damage, but have seriously fucked up my muscles. if you could please discuss your pain and the type of pain you have, I am very interested in bringing nerve/muscular damage from cathinones to the table here on bluelight. I think it seriously needs to be discussed and be an integral part of our analysis of its side effects and dangers
 
You must log in or register to reply here.
Top