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The Big & Dandy Methoxetamine Thread - 6th Dose (now you've gone and used it all up)

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God I'm glad I'm so good at using drugs (is that a talent? experiencing drugs well? wish I could parlay that into my career. all my relatives and friends would marvel at my passion and tell me how brilliant I am at indulging myself, and I would say, "damn right, losers").

=D I've thought along those lines before, too. Well, judging by your incredibly colorful and refined descriptions of drug experiences, I'd judge that you are pretty damn good at using altered states of consciousness as a form of art! You should write us a tutorial one of these days.
 
MXE Neurotoxicity and Psychedelics

In regards to any damage caused by NMDA antagonists with repeated usage, am I correct that the damage occurs due to NMDA dissociative neurotoxicity? Because supposedly psychedelics can prevent NMDA antagonist neurotoxicity according to an old-ish paper, though I don't understand this phenomenon very well or the doses/ratios required. Heres the paper you probably have seen it:

http://www.nature.com/?file=/npp/journal/v18/n1/full/1395108a.html&filetype=pdf

On a related note I recently had a wonderful experience with 120mg mxe snorted with 30mg 4-ho-met, and 3 hours later 15-20mg more 4-ho-met and a bit of jwh-250. Surprisingly friendly, and with the little bit of jwh-250, remarkably and memorably intense and fascinating. I laughed uncontrollably nd almost constantly during the peak of the cannabinoid, and my mind was very altered.
 
I appreciate your candor and words of caution, Transcendence and jazz hands. Glad I said something because I was curious about the long term effects of K and dissociatives in general... however, I do not feel that once or twice a week is anywhere near to being the same as daily use. I'm still quite new to the MXE experience, but during the 4 days that I took MXE each night, I could tell that it was too often - I ended up doing that because I had told so many friends about it and had many so-called "obligations" take it with them. With daily use; MXE lost it's efficacy, tolerance developed, and there was no revelation (as mentioned in a prior post).

While my initial plan is to take MXE over an extended period of time, that plan is not set in stone. If I start to experience negative effects, I'll reduce my frequency a bit or drastically. I've also spoken with my closest and dearest friend and expressed my plans. She is a very level headed person that rarely does drugs (though has in the past - so she understands them) - I've made it clear that if I start to show negative effects, that I want her to bring me back to earth. Granted once symptoms are apparent to the observer, they may already have become quite severe - but this is a nice extra layer of protection.
 
You'll probably be okay using it once a week. However, MXE is one of the most subtly and persuasively seducing drugs I've used. It's so hard not to ramp up use, because it really seems like it's perfect for every situation. You start to convince yourself that MXE will balance out whatever ails you on any particular day. You become very good at rationalizing its use.

After using MXE often, I started noticing that my thoughts and words were become more aggressive, more overly confident. It's really hard to describe how it changes your thought process, but you begin to see loops and interpret reality to confirm all of your thoughts and actions, both past and present. The confidence is empowering and nice in a way, but it goes overboard.

At the end of the month I began to get really paranoid and delusional about my health, something that is very uncharacteristic of me. Looking back on it now it seems absurd, but it was very real at the time. I was convinced that my apartment was growing toxic mold everywhere and it was the root of all my health problems. I thought I was developing bladder damage and even brain tumors. I was just way off balance.

The thing is, the changes in your personality are gradual but you don't notice them until you're way off kilter. Having a friend keep you in check might help, but you can't rely on it because they can't see inside your head, and by the time they report something is off you'll probably be deep inside the hole.

MXE was my favorite drug in the world at first, but it turned sinister toward the end. I started feeling really bad about myself, even though I would have thought that impossible when I first started using it.
 
^Great post!

I feel like I have totally ruined MXE for myself now after using it for 3-4 months almost daily (lately maybe 1-2 times a week). At first I had the whole hypomanic "this is a miracle drug/I'm reborn/my depression flew out the window/everything is fixed" experience but just couldn't help abusing the hell out of it. I've still had good introspective experiences this month but the last time I took it I just felt really.. REALLY dysphoric and ill. A cold, alienated, rotten feeling which I think some other people have described too...

Despite having a bit of an awful feeling about the drug and myself now, I still feel better than before I started using MXE. Like I am more sincere and in touch with myself and whatever inner issues I might have been dealing with for a long time. A humble feeling, now that the manic, delusional MXE-fiending me has been exorcised out of my guts. It has also somewhat relieved my social phobia and helped me form better relationships with some good people I otherwise may have lost contact with due to my tendency to very often retreat into isolation... I just hope I haven't damaged myself physically :(
 
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Thanks for sharing that, Transcendence. It gives me something more specific to watch for during my experiments. Interestingly, I have already experienced the over confidence you speak of to a degree. I found myself saying things that display an inflated ego - which would be exceptionally rare for me in the past (after I said some of these things I was almost shocked at how confident/forward they were). This "aggressive" behavior led to many positive outcomes, however - so I didn't consider it to be a bad thing. It was just that I now needed to develop a "filter" for what I was saying.
 
Had my first trial with MXE last night. I'll report more once I've had a few more trials, but I can say that I found 25mg orally to be significantly stronger than I was expecting. I was expecting just a taste of the experience, and I definitely got more than that. . . not that I'm complaining.
 
^Same here... On my first trial, I went with 20mg which was way stronger than I was expecting based on reports read here...

RE: confidence... It comes with a single dose IMO, it doesn't require repeated dosing. It fits pretty well along the lines of the superhuman persona I've heard described with PCP and other drugs in this class.
 
^Same here... On my first trial, I went with 20mg which was way stronger than I was expecting based on reports read here...

RE: confidence... It comes with a single dose IMO, it doesn't require repeated dosing. It fits pretty well along the lines of the superhuman persona I've heard described with PCP and other drugs in this class.

I am interested in this "superhuman" feeling one can get from this class of drugs. I haven't experienced it myself, but one time when I was having a chill MXE night with a friend of mine, he suddenly experienced what he later described as being a "super person", he sensed everything at the same time, sounds, images, movement, colors, everything. He was fully aware of the "now" with no filters. It only lasted a brief moment. I wonder why I haven't had this experience myself. Do you have any experience with ROAs or dosing regimens that are better than others at achieving this?

P.S. sorry if this post is a bit broken in the language, I am on MXE right now, ha!
 
Transcendence thanks for sharing your experience.

But I have to say my experience with using MXE mostly daily (3 to 6 doses of about 20mg - 50mg a day) , with a couple weeks off here and there.. and doing this for about the last 10 months. My mind has been 100% stable throughout this pattern of use. Yes MXE gives me more energy and enthusiasm, but nothing that would cause me to act irrationally or impulsively.

In this period of time I have been increasingly recognized at work for excellent performance and creativity. I have gone hiking and skiing and exercising in greater frequency. Skiing on MXE is my favorite thing ever :) ... and yes I am totally in control I am an expert skiier and have tackled some serious backcountry terrain under the influence of light doses of MXE. Plus it gives me more physical energy to go harder and last longer.

During this time I have helped organize a music festival that was a success and my relationships with my friends is at an all time high.

Problems I have had: One time at a concert I over-did it and also drank a big bottle of vodka and passed out on the floor for a minute, and somebody had to help me up. I was fine just had to sit down for a minute. Also I've found that repeated use will increase blood pressure but apparently not to dangerous levels.

But psychologically I've had only benefits, and really great benefits at that from MXE. I am more confident, more positive, and have adapted an "alpha male" mentality that demands respect from other men and women all love me ;)
 
I have read the threads some and searched but is there danger of respiratory depression on this stuff, especially mixed with alprazolam? I have taken my 1.5 mg that I am prescribed today. I just got back on yesterday after no use for a month so my tolerance is not that high. I am only planning on doing about 20mg tonight.
 
Yeah speaking of respiratory depression, how is it MXE with etizolam? Someone on the first page I think praised the combo of benzos and mxe but I don't know if it could cause a synergistic depression of the respiratory system.

Bluedolphin: Skiing on MXE sounds awesome! I have gone longboarding on it a few times and even though my balance was a bit off, I had a lot of fun!
 
I have read the threads some and searched but is there danger of respiratory depression on this stuff, especially mixed with alprazolam? I have taken my 1.5 mg that I am prescribed today. I just got back on yesterday after no use for a month so my tolerance is not that high. I am only planning on doing about 20mg tonight.

There is, but at those doses you'll be okay.
 
I figured as much. I haven't' taken any alprazolam for about 4 hours. Hopefully I am able to stick to 20-30mg tonight. =D
 
Last night was rather interesting. My friend overdid his "weekend dose" and ended up experiencing his first "M-hole", meanwhile I was on the border of one too, and was trying, while extremely messed up, to get him out of the voice chat channel so he didn't weird out all the people who didn't know he was tripping. Interesting night lol..

I think I'm intrigued enough to go to that place myself, so I think next weekend I'll try somewhere between 80 and 100mg sublingually :)
 
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