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Neuroscience and Pharmacology Discussion

Discussion of journal articles, drug science and other theoretical topics
The Holy Quadruplty
Do anihistamines bind to opioid receptors?
    • Like
Replies
16
Views
611
Feretile
Feretile
dalpat077
Please can somebody help me find my Fetty
Replies
3
Views
378
Nas47
Nas47
Nagelfar
Conolidine & newly discovered opioid receptor ACKR3
    • Like
Replies
5
Views
1K
plumbus-nine
plumbus-nine
nuke
  • Locked
I Like to Draw Pictures of Random Molecules
276 277 278
Replies
6K
Views
867K
thegreenhand
thegreenhand
jasoncrest
Forcing Loperamide through the BBB
4 5 6
Replies
118
Views
49K
DeathIndustrial88
DeathIndustrial88
Hammilton
Heroin and Quinine
Replies
11
Views
4K
Feretile
Feretile
P
Removal of the N-cyclopropylmethyl from buprenorphine and replacing it with an N-Me or N-phenethyl would create extremely high potency full agonists.
Replies
2
Views
254
Feretile
Feretile
acklac7
Pholedrine / 4-hydroxy-N-methylamphetamine questions
    • Like
Replies
4
Views
400
acklac7
acklac7
PtahTek
Alprazolam without the issues related to ... (Bromazolam (XLI-268)... just the (br) needed
    • Like
Replies
2
Views
1K
Feretile
Feretile
C
Why is hydrocodone so stimulating compared to codeine?
    • Like
Replies
2
Views
437
Feretile
Feretile
N
Why is Naloxone in Suboxone if it is 'inactive'?
2
Replies
33
Views
10K
MikeyView34
M
Nagelfar
Chemistry nomenclature question on reversed benzoate name (cocaine analogs, technical)
Replies
3
Views
368
4meSM
4meSM
JohnBoy2000
Response to drugs changes over time with cognitive/personality evolution, why? Neural rationale?
    • Like
Replies
1
Views
300
plumbus-nine
plumbus-nine
C
Novel opioid with Ki of 0.21
Replies
13
Views
1K
Feretile
Feretile
C
Does alcohol make you hornier or simply reduce inhibitions?
Replies
16
Views
955
JTemperance
JTemperance
Feretile
(±)-McN 5652/JNJ-7925476 A potent scaffold for a triple reuptake inhibitor - extensive QSAR allows almost any DAT-NET-SERT ratio.
    • Like
Replies
3
Views
613
Feretile
Feretile
plumbus-nine
REM sleep disorder - caused by dissociatives? morphine / venlafaxine
Replies
7
Views
539
plumbus-nine
plumbus-nine
Foreigner
Salicylic acid vs. aspirin
Replies
10
Views
847
sekio
sekio
A
maybe ketamine isnt as useful as we think?
    • Like
Replies
9
Views
593
Feretile
Feretile
Feretile
Novel (and simple) scaffold for new hallucinogenic compounds.
    • Like
Replies
4
Views
579
Feretile
Feretile
plumbus-nine
DMSO for transdermal delivery
Replies
2
Views
513
Skorpio
Skorpio
C
Why ARE ephedrine, cocaine, or amphetamines so much more potent than caffeine?
    • Like
2
Replies
36
Views
4K
red22
red22
M
How is the COVID vaccine metabolized?
Replies
4
Views
443
plumbus-nine
plumbus-nine
Jabberwocky
First scientific evidence that smoking cannabis impairs the lungs
Replies
8
Views
513
Skorpio
Skorpio
H
Why can you abuse drugs like Ritalin, but not Prozac?
    • Like
2
Replies
20
Views
2K
plumbus-nine
plumbus-nine
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