Wow, missed on IV and managed to go IM instead of SubQ. I would imagine subq would be pretty irritating as the blood flow there isn't as good as it is through the muscles. I don't have a proper scale plus all the reports of the caustic nature have me apprehensive to go IV. Also, a couple of nights ago it floored me. I had been going the insufflation route, and had been increasing the dosage by 5-10mg to find my happy spot, and it seems this stuff has the low ED:LD ratio that is similar to fentanyl. Luckily I stayed conscious and my sober-sitter didn't have to hit me with narcan. Polypharm was not a factor in this. The reports of this being similar to hydromorphone really piqued my interests as it is my favorite. Unfortunately it's not as close as I was hoping. I will share my observations after about a week with this stuff. I am not very opiate naive. Prior to trying, about 70-80mg of hydrocodone put me in my happy place (not quite nodding, but feeling very nice). I have experience with: Opium (smoked), codeine, hydrocodone, hydromorphone (IV, IM, oral, insufflated, plugged), heroin (smoked, IV, IM, insufflated, subq), oxycodone, oxymorphone, nalbuphine, pentazocine, buprenorphine, morphine (same ROA as H + oral, - smoked), fentanyl (hospital IV). General thoughts: it is about the same as oxy feeling wise. It is stronger than oxy on a mg for mg basis, as 10mg of U4 feels about the same as 30mg of oxy. The itching is intense; probably itchier than anything I've tried. I need about 40mg of zyrtec and 75-100mg of diphenhydramine to put a dent in it or 3 phenagren, or 60mg of mirtazipine. Luckily I don't mind it, and even like it sometimes. At higher doses there seems to be some kappa activity, but not intense. It doesn't have me fiending like I thought it would. It seems it doesn't start dropping off the receptor until about 10-14 hours after the last dose, judging by the feeling, the difficulty pissing, and the extremely constricted pupils. When it did wear finally, I feel like i was hit by a bus - I redosed at that point. I still have a bit left, but I have gabapentin, flexiril, lope, clonidine, cloneazapam (I can t take this though, as I need to piss clean to get in the sub clinic, even though its prescribed) - Speaking of which, it does not show up on a 12 panel test. My preferred ROA is oral. I've tried oral, insufflated, and plugging. I'll go though my feelings, pros/cons etc. Oral: pros - lasts much longer than any other ROA, Still a relatively fast onset, 10min then 15-20min to peak. Itch seems slilghtly dampened (probably just in my head though), only a couple waves of nausea. more room for error on dosing, probably the least risky as far as it being caustic - stomach is used to lots of caustic things, like hydrochloric acid et al. The tolerance builds fast - I only get one really good trip per day, any other dose is only for maintenance. All the other feelz as other opiates/opiods. Longest duration. Cons: Tastes pretty gnarly, need a higher dose than any other method comparatively speaking, no rush, seems significantly hindered by food intake, both on absorption and onset. Has the other normal cons of other compounds. Plugging: pretty much the same as oral - but for me, I needed the same dosage as oral - if not more. Might need to pop a laxative and clear everything out of there. Insufflation: pros - fastest onset, mild rush, powder is fluffy, so it's pretty much as easy as lining it up. Need about 50% less than oral. Cons: Shear fucking torture going up there - I've never had anything burn so bad going up there. Saline and mentholated spray barely helped at all. Day after 6 toots (gotta do smaller bumps) my sinuses were absolutely wrecked. I'm not going this roa again unless I can figure out how to make spray somehow. So all in all, the price and the fact it doesn't show up on a test are the biggest motivators in this. If I weren't worried about tests, I would likely stick to others.
