I personally find 6-APB to be one of the few RC's which has more pro's than con's. I'd almost deem it identical to MDA, though both chemicals have their slight differences. I personally think the 100-125mg range to be the sweet spot for it. My friends who've surpassed this dosage (150-175mg) experienced intense jaw chattering, and a migraine that influenced nausea, though I can't personally attest to whether or not this is a common occurence. Very glad to see this chemical finally made an authentic surge into the Research Chemical market. If you're able to find the authentic 6-APB (tan chalky/chunky powder), I'd definitely invest in it! Wonderful, intriguing chemical.