Let me at least break down the chemistry of the toads a little for you guys.
B.alvarius, the sonoran desert toad or colorado river toad, both produce and can secrete venom, it comes primarily from the two large parotid glands located approximately where its shoulders would be if it were a human lying face down.
In the case of Bufo marinus, the australian (or at least it is now, unfortunately. It was introduced in a failed attempt to control some pest species of beetle that were devastating crops, but they fucked up BIGTIME, both in that they neglected to factor in that these beetles lived at the top of the stems of the crops, whilst the toads are ground-living creatures, and also that they are extremely invasive, because they both breed prolifically and also they don't have indigenous predators to keep the numbers down. In OZ they organize toad round-ups and killings to keep down the numbers, and the REASON that nothing eats them (at least, if they do, they only do it once) is that they are chock-full of poisons. Wouldbe predators such as venomous snakes might well kill an individual toad, but once they try to eat it, it'll get its own back and kill the predator.
Not sure if there is ANY 5-MeO-DMT but of the tryptamine fraction of the venom, the vast part is bufotenine, 5-hydroxy-N,N-dimethyltryptamine, or 5-OH-DMT.
B.alvarius, the desert toad, contains both, mostly being 5-MeO-DMT with less being bufotenine.
In addition, the only means the venom can be safe to take is via the vaporized route, with the resulting fumes being inhaled.
The reason for this is that both B.alvarius and B.marinus contain a series of steroidal cardiotoxins which have an action not dissimilar to that of digitalis, oleandrin, and similar cardiotonic, cardiotoxic steroids. ORALLY or via injection, insufflation, or plugging etc. these would be highly poisonous. They either do not make it through, or are decomposed, it must be, via the vaporization process, or maybe the boiling point is too high for the venom vapor to carry the steroidal poisons through to the user.
These steroidal bufagins, bufagenins, bufotoxins etc. are heart poisons, that in small quantities, as with digitalis (foxglove, used in purified form, carefully at known doses these days as an important heart medication for certain types of cardiac ill health), slows, and strengthens the force of the heartbeat, in larger, toxic doses they cause arrhythmias and then stop the heart. Needless to say, this is not healthy and not to be recommended for anybody who isn't a filthy fucking police pigfficer
The effects of bufotenine itself are psychoactive, but it is a rough ride on the body, physically speaking. I've had purified, extracted bufotenine, sourced from species of Anadenanthera, vaporized and insufflated (this is a plant, which produces large pods with seeds inside which have a thick brown testa or seed-coat around them), and a common preparation from the crude beans is called 'yopo' or 'cohoba', some varieties depending on the indigenous culture and the species used contain DMT also, possibly only in the pod-cases themselves rather than the seeds, these are psychedelic snuffs used in countries located around the amazon basin region.
And I found it quite definitely hallucinogenic, when the bufotenine had been chemically extracted, isolated and purified, then vaporized, it did feel quite heavy on the body, with somatic symptoms present, a rapid heart rate, etc. occurring. It certainly wasn't 'a lethal poison', but it was rough. I remember seeing in front of my eyes a sort of visual phosphene network-like pattern, colored, like a threedimensional grid, with swellings present at the interface of any corner where the 'bars' met.
And otherwise, a darkening of the visual background with eyes closed. It did feel pretty body-heavy.
In any case, do NOT subscribe to the myth of toad-licking. The psychoactive portions, the tryptamines in the venom are not in any case orally active, at least, they do not affect the brain, being quickly attacked and destroyed by monoamine oxidase A.
The steroidal cardiotoxins on the other hand are perfectly capable of causing toxic effects if the venom were to be ingested, be it swallowed, stuck up your chocolate starfish, injected (injection would also, given the large content of foreign, animal proteins present in an animal secretion, would be asking for the development of an allergy and potential anaphylaxis when they are recognized as foreign invaders by our human immune systems), or powdered and snorted, that would make it easy to absorb the cardiotoxic steroids.
Since people report smoking the venom without succumbing to a digitalis or oleander-like poisoning, then it does definitely seem as though the vaped route cuts out enough of the steroidal nasty business.