On the 2nd of this year I went to Santa Cruz to try this. I hadn't eaten all day, and I had a small amount of caffeine in the morning. Then I drank 50mg in Kool-Aid and, my other 2 friends had 20, and 30mg. Within 10 minutes I was uncontrollably laughing until my head felt solid. Then we all started smoking weed and my whole visual field had altered into another perception of life. After about 40 minutes I got so worried that I was going to have a stroke, or a heart attack, that I isolated myself in my sister's room, and laid in her bed to calm down. When I looked in the mirror to tell myself I was fine, I couldn't believe who I was. The trip started at 4:00, and for about 2 and a half hours I was in hell. I could feel and visualize my every body part falling apart and becoming independent. I started to lose feeling in parts of my body, and then fell things like my face through the nerves in my leg...and I was just frightened. I was literally blinded by visuals, attempting to look up information on whether it was possible to actually have a stroke. I found a few reports saying people could end up with heart issues and that threw me over the edge. I was just in a loop of thought, thinking how disappointed my parents would be if I died, and how little I have done to make them proud. It was massively emotional, and my flaws were attacking me from every angle. Then at about 7:00, I kind of "came to" after a brief overwhelming experience that I seemed to have blacked out on (I can't remember much of what happened). I started to wave my hand around, and the trail made me so happy. I then started thinking, "Why am I worrying...I'm not dead, and the trip is almost over. Every thing is beautiful and I'm experiencing something truly amazing." Then I just jumped up in the biggest rush of euphoria and felt the true meaning of enjoying an experience. It was amazing. I started listening to music, and talking with all of my friends I was with. The night ended up pretty great. One downside to the night was after my sister came home at 8:30pm, we hot boxed her bathroom...and my friend that took 30mg was feeling nauseous. He started to walk into the living room, and my other friend helped him stand up straight, and then his eyes rolled back and he fell down. I thought he died and I almost started crying from how worried I was, and then he woke up and asked what happened. We weren't sure if he passed out from the hotboxing (we smoked about 15 jointes in a 4x4 bathroom with the windows closed for about 30-40 minutes), or if it was the 4-AcO-DMT. Although I felt responsible, everybody decided it was most likely the weed that made him pass out, but I felt awful. We watched a movie, and then went to sleep. It was one of the most insane experiences of my life. I think the dose, the weed, and the empty stomach effed me over, and I really should have meditated before hand. I never spend the time to get in touch with my mind before strong trips, and then I lose myself. I hope to one day try this again at maybe 40 or 45mg, with no weed, and a lot more concentration of my mind, rather than recreation. What a powerful substance.
PS- I have had trips very similar in intensity to this such as my 50mg 2C-I with an ounce of weed and an empty stomach on 4/20, and 10mg DOC and a few joints (high dose due to tolerance). Those trips were not AS intense, but the duration made it almost unbearable. I was so thankful for the 4 hour duration until the euphoria hit, and then I was upset it had to end.