i had a question for ZNegative, there has been times when ive only done 8mg or less in a day and it hasnt felt much different, if i worked my way to 4-8mg could i possibly get high you think?
Hey man, the reasons that you didn't feel different the few times that you only injected 8mg or less over the course of a day is because your body is used to recieving 16mg/day, so until you taper and stabalize at a given dose (which takes approximately 11 days, though you adjust almost 100% by day 4) you will feel either no difference, or you will feel slightly worse as you're taking a lower dose than you are accustomed to.
Luckily, suboxone/subutex is a fairly easy opioid to taper due to the fact that it is a partial agonist with a ceiling effect. Since Bupe's agonist effects plateau at a certain dosage (probably somewhere between 4 and 8mg when taken sublingually, but more like 2-4mg IV), maintaining at a dose above that celing is only keeping your body from going into withdrawals. So essentially, if the ceiling dose is 6mg, you should be able to jump from 16mg down to 8mg with little to no discomfort as neither dosage is stimulating your opiate receptors more or less.
Now, assuming that the ceiling is at 6mg, you could then still jump from 8 to 6 with little effort as well. However, for a few days you will probably feel some minor withdrawal symptoms right before you administer your bupe, as you are right on the cusp of the plateau. It's at this dose (remember, this is speaking hypothetically as 6mg isn't necessairily the cieling, especially if you IV, I'm talking about the ceiling dose in general), that you will start to experience a slight mood lift from the suboxone, as the amount of buprenorphine in your system is actually at times dropping
below the ceiling, so when you dose, there is more of a "spike".
Once you've stabalized well below the ceiling dosage, your suboxone will begin to feel a lot more like a full agonist. I don't want to lead you on to believing that it's going to feel like shooting heroin, but you will definately experience a pronounced mood lift and increase in energy and motivation. There is also a theory that at these low dosages where buprenorphine is no longer occupying all of the receptors, that it's full agonist metabolite,
norbuprenorphine can attach to the empty receptors, explaining possibly why low dosages feel more euphoric than others (though another explanation could be that your brain is just not saturated with bupe any more, so each time you dose, the effects are more dramatic... Kind of like how the first shot of heroin in the morning is always the best as you've let a significant ammount of time pass since your last shot during sleep...)
Now, unfortunately, it's been my experience that you really will not begin to feel these positive effects until you are shooting a milligram or less a day. If your shooting two mg, you might feel something, but that's still way too much. If you're going to continue using bupe intravenously, I recomend you start cutting the strength of your shots in half. If you're shooting 4mg 4x/day, lower it to shooting 2mg 2x/day, and keep going until youve tapered each shot down to .5mg. At this point, you can start messing around with how you cut back. When I shot subs, I liked my morning Fix to be large, so perhaps your first sot should be .5mg, and then cut the other two shots for the afternoon and evening down to .25mg, and then another .5mg before bed. You'll be amazed at this point by how little bupe it actually takes to ward off withdrawals, and when you stabalize at a point where your dosing .25mg or less you will really get a lot more out of it in terms of energy, and euphoria. In the end though, bupe
is a partial agonist, and the only way you will ever be able to get a high out of it comparable to heroin or oxycodone is if you straight up take a break for about three days and then dose.
I would, in conclusion, also recomend that you try rectal administration instead. IME, plugging buprenorphine and shooting buprenorphine feel exactly the same in terms of onset and "rush". The advantage with plugging though, is that the duration is much longer, which makes dosing only once or twice a day possible which is nice. I grew tired with IV bupe mainly because it started to feel no different than heroin in that I still had to fix at least three times a day, and it just wasn't rewarding enough when you can get the same euphoria through a ROA that doesn't involve sticking yourself with pins.