• BASIC DRUG
    DISCUSSION
    Welcome to Bluelight!
    Posting Rules Bluelight Rules
    Benzo Chart Opioids Chart
    Drug Terms Need Help??
    Drugs 101 Brain & Addiction
    Tired of your habit? Struggling to cope?
    Want to regain control or get sober?
    Visit our Recovery Support Forums
  • BDD Moderators: Keif’ Richards | negrogesic

Kratom raises tolerence or acts like a blocker to oxycodone?

Kratom's opioid component is infitismily tiny. Even so, unless you obtain actual leaves you really have no idea what you are consuming, let alone being able to quantify it. In the end, it will not have anything to do with your opioid habit. For example, the tiny opioid content is not mitigated by antagonists.
 
Well you asked for opinion's on Kratom. If it interact's with Oxy I don't know. 7-OHM's binding affinity, and that other present alkaloid's that are either mu receptor antagonist's or agonist's, should give atleast some clue's. Binding affinity is what matters and that of Oxycodone, the strongest wins.

But I never really labeled the WD's of Kratom as severe. Could be my body chemistry and taper. First it gives me energy/ drive/ calmness, doses of 3/ 5 gram of good Red Borneo/ Green Malay 3/5 times a day. Sometimes reaching 9 gram doses.

Then after experiencing this positive effects with only tiny higher doses needed. One day I'll wake take it and it won't work. And the good are replaced by semi-depressed feeling's and lack of energy. Then I tapered, stopped a month and it would work again. Untill the point of saturation or self limimtation of Kratom.

Might be I am unique experiencing this. But WD's from Kratom are ime a walk in the park.
 
Last edited:
Let's face it, oxycodone creates a tolerance to oxycodone. Long before I even had kratom I would get OC 20's in 1999 from a friend who was prescribed it. This friend liked street heroin better and he would give me handfuls of the 20's. In the beginning one 20 did it. After some time it took a lot more. I don't see that with morphine, at least with me. I also hear from people that have been on oxy for years, one person 80-100 mgs a day, never did kratom and still does not feel his oxy at all. Just keeps him well.

Yes kratom can temporarily raise tolerance. But that helped me stay away from pills. And it does take some time off to reset but it does.
 
Here is my experience with kratom, I take 300 mg of tramadol every day, thats 1 x 50 x 6 a day as a chronic pain patient. I have not really abused narcotics though I do periodically break them in half and will consume that extra half (25 mg) for a month or so at a time, which will result in a shortfall of 15 tabs at the end of a month, most chronic pain patients will end up in that routine, not really abusing it, but pushing the envelope nonetheless. The following pertains strictly to tramadol, taken largely exactly as prescribed, I have found that 5-6 capsules of kratom (red Maenga) forms a pretty decent analog to one 50 mg tramadol, though it will wear off far more quickly, usually any and all effects gone within 3-3.5 hours time. I am 5"10 175 lbs, and have been on tramadol for ten plus years, again every single day, thus I am obviously dependent upon the tramadol, and cannot just stop it absent a serious tapering schedule. All this said, if I am in shortfall (early) I have found that I can makie up that difference by substituting the very first dose of tramadol a day, with 2.5-3 grams of the kratom, thats 5-6 capsules. That kratom will last about 3.5 hours, and at the 4-4.5 hour mark I will then resume the tramadol, never taking them together! This has proven itself extremely effective at making up that shortfall, and I never take any more of the kratom than that one morning dosing, again keeping in mind I am taking that tramadol at 1 x50 x 6 a day. In other words I am not mixing up a huge amount of substances and throwing caution to the wind..... Good luck and I hope someone finds this useful.
 
give this thread a boost and see if we can get anymore experience and feedback...but I've come to the conclusion that Kratom should not be used if your an opiate user or it will sky rocket tolerance and render your opiates useless almost
 
I am so glad to hear others are having this problem. I went through a year or taking a lot of fent. Dirty 30s. Before that I was a casual/regular user of hydrocodone. Before fent I had a decent tolerance but could still achieve a good head nod or solid high without much effort.

I stopped the fent a year ago, and only occasionally get my hands on hydro or morphine sulfate. The rest of the time I am a daily user of kratom. And I can say I rarely, if ever, get anything from taking hydro, morph, or oxy. An energy boost maybe but that's about it. And I can take 150-200+ mg of any of those and pretty much feel completely normal.

It was only after reading through threads on here that I learned how much kratom messes with opiate tolerance. I haven't been able to lay off the stuff long enough to confirm it's the problem. But it's the only logical explanation. I know fent obviously affected my tolerance for a while but it's been over a year. Surely that's not the issue.

I hate it bc I still waste money on tabs hoping to just get one good buzz but I'll down 15-20 at a time and feel next to nothing. I've tried tagamet, plugging, snorting and the results never change. So I guess it's time to stop the kratom and hopefully get my tolerance down to a normal level. The bad part is I don't even care much for kratom. It's expensive, nasty as shit, and it will stop my bowels up for days.

I doubt this is very helpful to anyone but I wanted to share my own experience.
 
I dont take any pain killers but I have a bad habit with high dosed Loperamide for years. I was able to quit for a few days and lowered the dose from 140mg+ per day down to 70mg/day.

I started taking Kratom, 2g per dose a few times a day and I was able to rapidly taper the Loperamide with no withdrawal symptoms except trouble sleeping. Went from that 70mg/day to 30mg today. I dont even know if I needed the 30mg loperamide today its just I have something big to do tomorrow and didnt want to risk dealing with any withdrawals.

I have no idea how Loperamide works but Kratom seems to help alot.

Ill wake and take 4 capsules of kratom for 2g dose, then another 30 minutes later ill take another 4 capsules and I feel good till the afternoon.
 
hey team - 24 yrs old been using oxy since I OD on a dirty 30 when I was 19… not sure why that was the catalyst to my opiate addiction but it was. Started with saris/ benzos in high school been on every benzo/sleeping pill/ssri/remeron/laxiative/Suboxone combo ever since. Last year I detoxed off of 16-24 mg of subtext and 15-30 mg of Valium daily. It was hell and took 64 days. Was in acute withdrawal for the first 24 days then finally could WALK again after 30ish… anyways the last year I have been back on the codine/oxy/hydro vibe and recently my doctor prescribed me buprenorphine again. I took 1x 1/2 of a 2mg buprenorphine tablet 24 hours after taking 45 mg of oxycodone two weeks ago. It threw me into precip (precipitated withdrawl) and then I didn’t feel oxy again for about 5 days. There has been a few kratom attempts here and there my last one being today. I haven’t had any painkillers since Monday it is now Friday and I drank half of a feel free drink which is apparently 20mg of kratom and then went and bought the opms extract gold liquid and capsules. I took one dose (1/3 cap) of the liquid kratom as well about 2 hrs after and so far only raised heart rate and anxiety. In the past, I’ve taken what I believe to be too much and woke up in the middle of the night with a headache, heart pounding, and very itchy. I feel like sometimes my kratom either doesn’t kick in or kick in very delayed. Anyways, I’m considering going back to oxy as I am a weekend warrior when it comes to painkillers but I’m a bit worried that I’m going to have to take a lot of oxy/hydro as it seems like kratom acts very similar to buprenorphine in the way screwed up my tolerance like our friend here who started the thread. I’m not necessarily looking for any specific answer, but any sort of advice or two cents I would love to hear. Could I try oxy tonight? Am I not taking enough kratom? Do I need to space them out more since one is a partial agonist and others are full agonist? Please let me know how I can achieve my desired affect whether that be kratom or oxy/hydrocodone again. I will take buprenorphine if neither work, but that’s my last result as it’s the only prescription I can still get due to my overdose. All this is appealing to me since I deal with chronic G.I. issues and happy to get more into that once the thread gets going. Pain isn’t fun and living with it is worse. Please send some advice!
 
I don't have any great advice but bupe and kratom def mess with opiate tolerence almost to the point its not worth taking but we still take it hoping it will be different this time ...do I get a little relief sure but its just very dull ...the further you can get out from last dose of kratom or bupe the harder it will hit but I wouldn't expect it to hit like it once did... I cant speak much about kratom I've only tried it that one time and as soon as I found out it killed my opiate tolerance I aborted...But I can speak on opiates and its such a hard game to play and it wears you down slowly but surely.. less is always better ...I don't have any magic answers but I know your pain and I wish you the best.
 
My experience with Kratom and percocet was that they cancelled each other put and it suuuucked. Same with suboxone. Everyone is different bit I wouldn't take them together. I did because I was going through withdrawals. I had gone from dilaudid to being cut off and put on a small amount of percocet and it was awful. Anyway, maybe I'm wrong and it's because I was in withdrawals but it seemed to negate the percocet.
 
Top