Here is my experience with kratom, I take 300 mg of tramadol every day, thats 1 x 50 x 6 a day as a chronic pain patient. I have not really abused narcotics though I do periodically break them in half and will consume that extra half (25 mg) for a month or so at a time, which will result in a shortfall of 15 tabs at the end of a month, most chronic pain patients will end up in that routine, not really abusing it, but pushing the envelope nonetheless. The following pertains strictly to tramadol, taken largely exactly as prescribed, I have found that 5-6 capsules of kratom (red Maenga) forms a pretty decent analog to one 50 mg tramadol, though it will wear off far more quickly, usually any and all effects gone within 3-3.5 hours time. I am 5"10 175 lbs, and have been on tramadol for ten plus years, again every single day, thus I am obviously dependent upon the tramadol, and cannot just stop it absent a serious tapering schedule. All this said, if I am in shortfall (early) I have found that I can makie up that difference by substituting the very first dose of tramadol a day, with 2.5-3 grams of the kratom, thats 5-6 capsules. That kratom will last about 3.5 hours, and at the 4-4.5 hour mark I will then resume the tramadol, never taking them together! This has proven itself extremely effective at making up that shortfall, and I never take any more of the kratom than that one morning dosing, again keeping in mind I am taking that tramadol at 1 x50 x 6 a day. In other words I am not mixing up a huge amount of substances and throwing caution to the wind..... Good luck and I hope someone finds this useful.