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The Big & Dandy MDAI Thread

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Evening all.

Tried about 125mg MDAI last night, and had a similar experience to most reported in this thread already - fairly mild, not much of an impact.

I'm planning on taking this again in conjunction with Methylone next time (probably in a week or so), and will let you know how I get on with it then.
 
I think until mr dark brown becomes cleaner I will be suspending further experiments. Though of late b1 and dài combo been great
 
^i'm in the same boat in regards to the dark brown stuff. Kinda wanna do some further testing, but not enough to wash the stuff myself. Also, word on the street is the current batch of dark brown's almost all gone ;). Hopefully the re-up will be cleaner.
 
Is it likely that MDAI has affinity for the 5ht-2b receptors leading to cardiac fibrosis like other SE releases such as Chlorphentermine. Making it a concern for a long term use as an anti-depressant?
 
Is it likely that MDAI has affinity for the 5ht-2b receptors leading to cardiac fibrosis like other SE releases such as Chlorphentermine. Making it a concern for a long term use as an anti-depressant?

yes, it's likely.

5-HT 2B agonism could be required for 5-HT release. i've once posted a link to a paper somewhere on bluelight, that found abolished serotonin release when mdma was given with a 5-HT 2B antagonist.
 
5-HT 2B agonism could be required for 5-HT release. i've once posted a link to a paper somewhere on bluelight, that found abolished serotonin release when mdma was given with a 5-HT 2B antagonist.

What's also the likelihood of their being a negative feedback loop, where 5-HT 2B antagonism reduces serotonin release. But there is a lack of positive feedback, so beyond natural agonism of this same receptor would insignificantly boost SE release?
 
Based on personal experiences would you recommend starting with 130mg with the option of a 50mg booster or instead start with a larger dose (150-180mg)? Have read and re-read forum, seems there is a disagreement as far as dosage.
 
Also, do you think combining pseudoephedrine could produce a mild dopaminergic effect that many say is lacking?
 
Can this be taken with tramadol? Has anyone ever? I know MDMA + trams have complications, does it apply to this?
 
Also, do you think combining pseudoephedrine could produce a mild dopaminergic effect that many say is lacking?

No.

Can this be taken with tramadol? Has anyone ever? I know MDMA + trams have complications, does it apply to this?

The interaction should be similar in terms of serotonergic fx, but not with NE or DA, so yes, the complications should be similar, but without synergistically lowering the seizure threshold.

ebola
 
Based on personal experiences would you recommend starting with 130mg with the option of a 50mg booster or instead start with a larger dose (150-180mg)? Have read and re-read forum, seems there is a disagreement as far as dosage.

I did 150 mg oral and followed it up with 50 mg snorted.

This has been my only experience with MDAI thus far.

My girlfriend with much less drug tolerance in general did the same and we both found that it would be better just to take more off the bat. We're going to do 200 mg orally off the bat next time.

Personally, I'd say just do 180 mg all at once. It's not intense by any means, but enjoyable.

Also, do you think combining pseudoephedrine could produce a mild dopaminergic effect that many say is lacking?

The one time we did MDAI we found it to be definitely more sedating than stimulating, so combining some pseudoephedrine should help.

After I try 200 mg for my 2nd experience, I'm going to try 125-150 mg combined with around 60 mg of dextroamphetamine, so adding stimulants seems to be popular with this one.

Let us know how it goes!
 
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Also, do you think combining pseudoephedrine could produce a mild dopaminergic effect that many say is lacking?

I don't know how effective pseudoephedrine would be in this context. I've used M1 and d-amph for this to good effect. Some people have had success with mdpv, but i haven't tried it personally yet.
 
I don't know how effective pseudoephedrine would be in this context. I've used M1 and d-amph for this to good effect. Some people have had success with mdpv, but i haven't tried it personally yet.

When using MDAI and d-amphetamine, what were the doses for each?

I'll be using crushed up extended release d-amph that comes in little orange spanules. I don't know if that makes a difference.
 
When using MDAI and d-amphetamine, what were the doses for each?

I'll be using crushed up extended release d-amph that comes in little orange spanules. I don't know if that makes a difference.

I used 120-200mg MDAI with ~10-20mg d-amph, and even a couple times with less than 10mg. I also used the time-release type you referred to. Removing them from the capsule and crushing them does seem to negate the "time release" aspect. I don't take d-amph often, and am rather sensitive to it, plus I dislike some of the peripheral effects it causes, so I kept my dose pretty low. If you take it often or are insensitive to it otherwise, you may want to dose it a little higher.
 
I used 120-200mg MDAI with ~10-20mg d-amph, and even a couple times with less than 10mg. I also used the time-release type you referred to. Removing them from the capsule and crushing them does seem to negate the "time release" aspect. I don't take d-amph often, and am rather sensitive to it, plus I dislike some of the peripheral effects it causes, so I kept my dose pretty low. If you take it often or are insensitive to it otherwise, you may want to dose it a little higher.

I am assuming I'm a little insensitive to it. The other day I used 45 mg to help study with my group for a group project and I was definitely not acting wired enough to be remotely noticeable.

Do you know if they synergize well? Does taking 10 mg of d-amph with MDAI make the 10 mg of d-amph more effective?
 
MDAI doesn't really have any stimulant properties. Alone is almost sedating, definitely relaxing. Combining the two results in a somewhat MDMA like high, though certainly not identical, just the closest thing I could compare it to.

I rarely, if ever, take more than 10mg d-amph at a time to study. I would go with whatever your normal dose of d-amph is.
 
do you guys think MDAI would be a good add on to shrooms? the word relaxing keeps coming up in conjunction with mdai, so its got me wondering. ?
 
I cannot wait to see the tail end of the brown stuff it's a neusance to work with . Hopefully the supplier will get the next batch nice and clean . More tests to follow so far b1 and mdai combo for us works nice.
 
I recently acquired some MDAI, which must be from a new batch. The color is an off-white, kinda tannish gray. It reminds me of nothing so much as the color of dry mortar.

I should point out beforehand that I drank half a bottle of one of those six hour energy drinks. I was planning on a pleasant day doing yardwork.

Based on comments posted here I assumed an average dose would be around 100 mg and decided to try a third of that

Two hours after the energy drink I dissolved 30 mg in a glass of water and downed it. Well...ummm...this batch must be WAY more potent. Fifteen minutes after ingestion there was a strong comeup. No wondering if I was feeling anything, there was nothing subtle about it. Vision got brighter, daylight was harsh. Huge body rush. I was alarmed at the surge, and thoughts of deaths caused by mislabeled RCs caused a lot of anxiety. Heart pounding, and sweating profusely I sought out my wife to help keep me grounded. I had not told her that I was planning to trip because I thought this would be a light, maneageble dose. She was surprised but accomodating and just a few minutes snuggling got me calmed down. At the half-hour mark I was at a plus +++. We had a nice conversation about work/life/relationship issues and an hour or so later I decided to take a shower to wash off the sweat.

Shower felt good. I could feel every rivulet of water running down my back and legs. I alternated hot and cool water because it felt good. Feeling refreshed and more balanced I dried off and got dressed. By this time I was over the peak and settled into a long plus ++ plateau.

Walking around the house was difficult. I felt drained of energy, but at the same time with a strong body buzz, shaky and unsteady. Not very pleasant. How much of this was the MDAI and how much was the energy drink is anybody's guess, but I have never had that kind of reaction to energy drinks before. Possibly a synergy between the two.

I went to the fridge to get my favorite psychoactive substance, a big glass of milk. It noticeably calmed down the shakes, and got me into a better space.

Ok time for music. Headphones on and cue Pink Floyd, Enigma and Flim and the BBs. Nice enhancement, but not as good as pot. Mild CEVs. I had trouble getting immersed in the music as thoughts kept intruding, probably remnants of my anxiety.

Two or three hours later it was time to walk the dogs. Still a little unsteady but much improved. Dogs seemed to be grooving on my energy, but I still wasn't quite where I'd like to be.

Got home, had some dinner with my sweetie, still tripping. Food didn't taste very good, despite having one of my favorite dishes. Then we watched a black & white western, which was a lot more interesting than I normally find these things. So here I am nine hours into the experience and it's finally beginning to tail off.

Mild headache, but sleep came easily. I awoke at 3 AM with a pounding headache. Not wanting to add more drugs to my system, I waited it out, falling back asleep in 45 min or so. Slept in late and felt OK but a little shaken, no headache.

There are comments posted here about MDAI being subtle, mild and fairly uninteresting. I found it to be none of those, and this was at one third the dose others have reported.

I intend to explore this compound further, but at smaller doses and without the energy drink. I think it can be much more pleasant than this experience would indicate.

If anyone here gets some of the new batch keep my comments in mind and as always start low and work your way up.
 
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