I need some dosing advice, I have a close person who is dead bent on trying something psychedelic, but they're on a SSRI (escitalopram 10mg/day) so they cannot trip with common psychedelics such as mushrooms. They even tried stopping their medication to trip, despite my advise against it, becoming pretty badly depressed after only three days of absistence having to restart their medication. So to satisfy their curiosity, it would seem like methoxetamine has to fulfill the role of the psychedelic.
First of all, is something like 30mg (or 60mg spreaded dosage) of MXE safe to take with such an SSRI? Would this be a good dose for someone who hasn't had any experience with psychedelics or dissociatives (not sure about dxm) before (but have smoked more than plenty of weed and taken other drugs, except stimulants)? They want a meaningful experience but obviously not an overwhelming one. If it ends up happening, I will be their trip sitter and responsible for the dosing, so I would really appreciate any input. I am experienced with psychedelics and dissociatives myself, but my adventures with MXE have always been with rather high doses so I don't know how to approach the substance with lower dosage. Perhaps some boosting is in order?
I would especially appreciate experiences of people who were inexperienced with tripping/dissociatives and had their first truly psychedelic/dissociative experiences with MXE.