Torabora
Bluelighter
- Joined
- Apr 30, 2010
- Messages
- 190
Nobody seems to know how toxic it is relative to ethanol. AFAIK, we'd need to know the toxicity of all metabolites of the chemical (assuming that it IS metabolized? someone said earlier that it isn't metabolized in the liver...), and even without metabolites, its impossible to know if the 2-methyl-2-butanol itself is toxic without there being research done on it.
about toxicity and metabolites: http://toxsci.oxfordjournals.org/content/49/1/15.full.pdf
paper suggests that it is metabolized to 2,3-dihydroxy-2-methylbutane via p450 oxidation (~35%) and gluconoridation (~23%) and the 2,3-dihydroxy-2-methylbutane being further metabolized via gluconoridation but they dont give a conclusion about toxicity for humans.