So my partner is going through a bout of anxiety and depression. He's never used a disso before, but is considering taking one tonight. Given the late hour, it's probably best to go with a short acting one. Do you think MXPr, 2-FDCK, or MXE would be a good place to start?
MXE would be my choice, I find that it has pretty profound antidepressant qualities and is just lovely in all respects. I'd start with a pretty low dose since he hasn't taken dissos before. Some people don't really like dissociatives. MXE at 20mg or so would be hard to have a bad time on.