Thanks for the reply. Well, as the creator of the thread, I do say that it would be much appreciated if a moderator did fix the typo in the title so as to get more exposure. Perhaps someone out there who has access to scientific journals that I don't might be able to shine some light on this topic. I've searched PubMed and Google Scholar, but as always, the majority of the articles found in those scholarly databases are for purchase only (which is fine, as a scientist you've got to make your money somehow). I don't have a problem with plugging, though I've never done it. I just find it strange that such a common drug (at least in this Bluelight community) has no data in terms of bioavailability across various different routes of administration. The megathread for bioavailability/half-life is great, but unfortunately I couldn't find what I was looking for. Specifically,I was looking for intranasal vs. oral bioavailability. Perhaps it is just the fact the when insufflated, the effects are felt almost immediately, leading to the illusion that it might have a great intranasal bioavailability. Referring back to the megathread, some benzos in that thread are stated to have a higher oral bioavailability than intranasal; in other benzos the opposite is said to be true.
Also, I wasn't aware that insufflating pills was so bad for your lungs. I know injecting them is, so I've never done it. I've never gotten a nosebleed from insufflating pills -- and I've snorted many. Not trying to argue that just because it's not painful for me or that I've never bled from it that I believe it's not harmful. I've just never heard that it's so harmful.
Well, thanks again. Please add any relevant info if anyone comes across it.
