• Select Your Topic Then Scroll Down
    Alcohol Bupe Benzos
    Cocaine Heroin Opioids
    RCs Stimulants Misc
    Harm Reduction All Topics Gabapentinoids
    Tired of your habit? Struggling to cope?
    Want to regain control or get sober?
    Visit our Recovery Support Forums

Benzos Xanax, Oxy and Promethazine...will it kill me?

Oxy8_8

Bluelighter
Joined
Apr 24, 2013
Messages
489
Location
England
I realize there's a lot of text here. If you're kind enough to answer but just wanna see a quick question, jump to the last two paragraphs :) haha.


I take a lot of Phenergan (Promethazine Hydrochloride). I take around 100mg a day, occasionally a little more. I started taking it because of the opi-itch. And it worked excellent for that. I noticed it also helped me sleep better (50mg before bed). And it reduced my anxiety all day if I took one (25mg) in the morning and one (25mg) in the afternoon. It also helps with the nausea I get (not that much alone, but it gives a notable boost to my Domperidone). too. Basically, I think the stuff is fantastic and helps with many of my problems making my life that bit easier.

Generally, my life is not easy. Physically, I mean. I'm only 23 years old but last November I almost died of an extremely severe acute attack of pancreatitis (brought on my 11 years ofbulimia and 3 years of alcoholism, but I won't go into those as I am almost 7 months "clean" of both and they are irrelevant to this post).
Despite the low odds, I was very lucky and survived. However, I live with severe chronic pancreatitis and fibromyalgia. I also had a seizure (alcohol withdrawal) a year ago and have two collapsed vertebrae in my lower spine. Basically, I'm in a SHITLOAD of pain. I take 200mg of a mix of OxyContin (sustainted-release pills) and oxycodone (instant release capsules) a day. I will admit to sometimes abusing my prescription. I could probably get by on 140 oxy plus Tylenol 3. And I sometimes take up to 280mg a day.
Long story short, I suffer intensely severe pain every day. I am also addicted to opiates.

I have been diagnosed with "severe mixed anxiety-depression" since I was 11. Stupid doctors thought "talk therapy" was best. BullSHIT. I was put on Sertraline (Zoloft) at 19 and it 100% cured my depression and changed my life. To me that drug is a fucking MIRACLE.
However, it didn't do too much for my anxiety, although it helped a little.
Doctors have always refused to prescribe me benzos (they rarely do in the UK), particularly because of my history of alcohol dependency.

Crippling anxiety and panic attacks literally ruined my life. I was bullied for it at school which double the issue. My parents never understood and made things worse etc etc. I finally decided enough was enough: so I took matters into my own hands and have been taking 0.5mg of alprazolam (xanax) three times a day for the past two weeks and it's great.

But like my pain meds, I do sometimes abuse them, although not to crazy amounts: I have never had more than 2mg at once and never more then 3mg in one day.

I know that promethazine potentiates opiates. Not a lot but enough to help the nice warm sleepyness. However: I searched online to see if the same was true about promethazine with benzos, but I got nothing but warnings and horror stories!

I am worried now. Is taking oxycodone, alprazolam and promethazine together dangerous? Taking into consideration that I know all the drugs and my tolerance very well and will be sticking to small-medium amounts of all???

Most likely:
Oxycodone: 60-80mg
Promethazine: 50mg
Alprazolam: 2-2.5mg
 
Last edited:
Dose low on everything. You're still rolling the dice, though. It's a totally unpredictable combo.
 
That is not a low daily dose of alprazolam, sorry to tell you. I mean, compared to people on bluelight, sure that's a low dose, but not in terms of how it's usually medically prescribed to someone who just started taking it and should have a low tolerance....

I'm relatively certain that you aren't getting legit scripts for these, what happens when you run out and can't get more?

Also, with alcoholism, you're pretty much primed for a benzo addiction, IMO, no wonder the doctors wouldn't script them for you, they're not total idiots.

Many people have died from the combination of opioids and benzos. Course, they are scripted all the time together, under the supervision of a provider, typically in low, therapeutic dosages, typically not more than 10mgs a day valium or the equivalent.

Alprazolam, bought off the street, used by someone who is self-medicating, and taking large doses of opioids daily, nothing could ever go wrong with this scenario :!
 
That is not a low daily dose of alprazolam, sorry to tell you. I mean, compared to people on bluelight, sure that's a low dose, but not in terms of how it's usually medically prescribed to someone who just started taking it and should have a low tolerance....

I'm relatively certain that you aren't getting legit scripts for these, what happens when you run out and can't get more?

Also, with alcoholism, you're pretty much primed for a benzo addiction, IMO, no wonder the doctors wouldn't script them for you, they're not total idiots.

Many people have died from the combination of opioids and benzos. Course, they are scripted all the time together, under the supervision of a provider, typically in low, therapeutic dosages, typically not more than 10mgs a day valium or the equivalent.

Alprazolam, bought off the street, used by someone who is self-medicating, and taking large doses of opioids daily, nothing could ever go wrong with this scenario :!

The starting dose of alprazolam is 0.25mg to 0.5mg a day. For anxiety the highest doe is 4mg, more than double what what I usually take. Plus, you can take up to 10mg a day for panic disorder which I have.

I got a warm, mild euphoria and well asleep on my laptop lol. I took 3mg Xanax (a very recreational dose for me) and stayed low on the oxy. That was my mistake. It's best done the other way around.

I'm chew an OC 8 (been chewing or insufflating every 4 hours or so all day) and start with 0.5mg xanax. Then add 0.25mg xanax every half hour until I reach desired results (maybe adding 20mg oxy hourly).
I'll just take 50mg promethazine (I take 50-75mg pretty much every night)
 
Yeah, it'd definitely better to take less alprazolam than that, I'd black out and I've taken benzos for many years. Always a small dose, as rarely as possible, and I still have great results with .5mgs alpraz. I know what the prescribing guidelines are, but should also mention that they're meant to be taken for as little time as absolutely possible, as they are very addictive and the withdrawal syndrome from benzos is absolute shit!

Sorry to lecture, but I've been answering your questions for weeks now, so if you OD, I'll feel like a failure! haha

Anyway, the promethazine is only going to make you more sleepy, as you find, but there aren't any hard drug interactions with what you're taking.

If you don't believe me about the benzos, pop into EADD and ask the lads how easily and quickly you can get addicted to alprazolam, it's no joke!
 
I have overdosed twice from a similar combo of heroin, xanax, and diphenhydramine I would highly recommend against it
 
Will it kill you?: If you are not tolerant, yes... We really can't possibly answer that.

Should you take the risk?: No...

Would I remove the promethazine?: Yes...
 
your a dumbass...if you have to ask.. "will this kill me? (and yes it will) ..than ..fuk...people like you are why drugs r illegal
 
I have overdosed twice from a similar combo of heroin, xanax, and diphenhydramine I would highly recommend against it

thumbs up to this guy for real world exp., i only say this cuz your experience is ...shall we say reminiscent
 
Last edited:
your a dumbass...if you have to ask.. "will this kill me? (and yes it will) ..than ..fuk...people like you are why drugs r illegal

You know, what he's asking isn't really something your average layperson would know about pharmacology. Censuring questions like this is only going to increase the danger to someone's life and keep them from asking for more, necessary information.
 
Yeah, it'd definitely better to take less alprazolam than that, I'd black out and I've taken benzos for many years. Always a small dose, as rarely as possible, and I still have great results with .5mgs alpraz. I know what the prescribing guidelines are, but should also mention that they're meant to be taken for as little time as absolutely possible, as they are very addictive and the withdrawal syndrome from benzos is absolute shit!

Sorry to lecture, but I've been answering your questions for weeks now, so if you OD, I'll feel like a failure! haha

Anyway, the promethazine is only going to make you more sleepy, as you find, but there aren't any hard drug interactions with what you're taking.

If you don't believe me about the benzos, pop into EADD and ask the lads how easily and quickly you can get addicted to alprazolam, it's no joke!

Thanks for all the help! I think I'm now out of the noob category and won't be asking much more haha. I did blackout and fall asleep. From now on I'm gonna use either benzos OR promethazine for sleep. Never both haha :).

I know I've asked a lot of questions, and ones that may make me sound kinda dumb (I'm not, honestly) I just wanted to know exactly what I was getting myself in to. I hope I haven't made a fool of myself :\
 
Pleasure Oxy :)

Never really thought you were a noob, but glad you keep asking! BL has soooo much expertise and experience in drugs between all the members, it's fantastic. I mean, we're here exactly for this, to keep people alive, so never feel bashful about asking a question that regards drugs and your health.

Cheers =D
 
Oxy8_8 said:
Doctors have always refused to prescribe me benzos (they rarely do in the UK), particularly because of my history of alcohol dependency.

Crippling anxiety and panic attacks literally ruined my life. I was bullied for it at school which double the issue. My parents never understood and made things worse etc etc. I finally decided enough was enough: so I took matters into my own hands and have been taking 0.5mg of alprazolam (xanax) three times a day for the past two weeks and it's great.

Wait...in another post you said your dad was so mad about your lack of treatment for anxiety he took you to a private doctor who is scripting the xanax? I'm confused.

But yeah I think your xanax dose is a bit high, you hear things on BL about people taking ridic amounts of it but that's not something the average person can do.

Anyways sounds like you already did it.
 
Mixing what you are taking is like playing with fire. Xanax is horrible. After four weeks my tolerance crept up super fast and the interdose wd was killing me. Careful playing with fire that you dont get burned.
 
i'm going to second what a lot of people have said on here & say that xanax is a little bit of a tricky thing to be playing around with... my mom & i are both rx'd .25mgs twice a day as needed for anxiety & we both have gone through periods of tolerance creeping up higher than what it should be... i've never taken more than 1.5mgs in a day, but only because i stopped myself from getting my tolerance even higher. i brought it back down & now i take maybe .5mgs in a day on an average day for anxiety, but i take days off frequently to ensure it still works well at that dosage when i need it too. i've never gone through hardcore benzo withdrawal, but i have gone through opiate withdrawal (more than once) & after reading about how life-threatening benzo withdrawal is on BL, i never ever want to experience it for myself.

i'd take days off with the xanax when you can, maybe use it every other day or every third day, or take a couple days off & a couple days on, whatever you find works best for you. it's just really easy to let your tolerance get higher & higher without you consciously realizing it.

be careful, we all care about you!!! <3
 
Top