Well sure,ive had euphoria from Xanax but was taking then with Stilnox(i dont remember the substances name-its a benzo,semi-weak imo) and was/am an opiate addict so H was always involved.
That being said ,once on the 3rd day of a heroin detox,like a typical retard i took 11 2mg Xanax bars(22mgs) along w Valium and some codeine and Tramadol,all prescribed by a doc to help with the Heroin WDs and i felt nothing except slightly dizzy.
So ultimately i guess it comes to the right dose and the right combo for everybody.