Would Salvia take away your opiate nod?

[cAMP]

Opiates act on the mu-opioid receptors which accounts for their nice effects (euphoria etc)

Agitation of the kappa-opioid receptor negates the effect of mu-opiod agonization. Salvinorin A is a potent kappa-opioid agonist and its responsible for the dysphoria concomitant to smoking sally d.

So I'm thinking of a pod tea salvia combo. If you are nodding hard on them pods would a few Sally D hits take away your nod for ~15mins?

I'd personally test it on my self but I have only living salvia and no pods at the moment.

 

[fryingsquirrel]

I think it safe to assume you won't be nodding for 15 minutes, you'll be off in salviaworld. Why you would want that I haven't a clue.

 

[MikeHawk]

Isn't the opiate nod a subjectively positive effect? It certainly is for me.

 

[cAMP]

I know that the majority of people would be pissed if taken away from their nod

I would try out this combo simply due to scientific interest. I can afford 15mins in salviaworld when I have 14hrs of nodding.

 

[fryingsquirrel]

I'm kinda curious myself as to the interaction of receptors. Please post when you get a chance to try it out.