Help! Worth doing ketamine with a schizophrenic uncle

[bladeedraingang]

Basically my uncle got severe schizophrenia from being a pothead in his 20s, for this reason I try to avoid weed and lsd. How risky is doing ketamine for me, I’ve done it once b4

 

[Shipurata]

I would personally avoid hallucinogens or stimulants if I had schizophrenia or bipolar in the family. It's not worth the risk.

 

[bladeedraingang]

I take vyvanse like everyday,prescribed!

I would personally avoid hallucinogens or stimulants if I had schizophrenia or bipolar in the family. It's not worth the risk.

 

[mr peabody]

Ketamine is strictly contraindicated for individuals with schizophrenia because it blocks NMDA receptors, which can trigger hallucinations, severe paranoia, and a dangerous return or worsening of active psychotic episodes. [1]

Effects on the Brain

Worsens Psychosis: In people diagnosed with schizophrenia, ketamine actively destabilizes brain circuits, sharply increasing positive symptoms (like delusions) and negative symptoms (like emotional numbness). [1, 2]

 

[Didgital]

I'm gonna 2nd @mr peabody

Ketamine makes even regular people delusional so I can't imagine what it would do to someone with schizophrenia.

That said.. just cuz you're uncle is schizo, doesn't mean you are.

 

[petateom]

If your uncle has schizofrenia you posibilities aren't that high, its around 3-4% while for a normal person would be 0.5%. I'd still do the experiments, but being way more cautious unless you have an schizoid personality or you are too young (better wait until the late 20s or early 30s).

The lifetime risk of schizophrenia for the general population is estimated to be 0.2 to 0.7% (13).

"The recurrence risk of schizophrenia in the siblings of a patient is 10%, and in the children of patients, the risk is approximately 10%. The risk for second- degree relatives is approximately 3-4%"

Source

 

[FractalPerogys]

Ketamine when done in excess (as well as most dissociatives) WILL cause mania and possibly psychosis in those prone from excess glutamate when you come down. Dopamine as well as glutamate cause mania and psychosis in high enough amounts, and likely other excitatory neurotransmitters.