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Will taking LSA one night give me a tolerance to LSD for the next night?

K20aCTR

K20aCTR

Greenlighter
Joined
Aug 28, 2008
Messages
6
I am thinking about taking about 8 hbwr seeds tomorrow but I am going to Asheville for a show at the Orange Peel the following night and would love to find some acid there. I dont want to have a tolerance for the second night so will taking LSA give me somewhat of a tolerance to LSD for the next day?
 
Lots of psychedelics have cross tolerance, and seeing as LSA and LSD are similar in structure, I would say for sure. Not 100% on that though.
 
LSD is such a strong agonist it usually overcomes the tolerance from other psychedelics; you might have to take a bit more acid than you normally would, though. If it were me I would just save the HBWR seeds for another time, though.
 
The Winner!! said:
Lots of psychedelics have cross tolerance, and seeing as LSA and LSD are similar in structure, I would say for sure. Not 100% on that though.
Click to expand...

It is not structure that determines tolerance,l but mechanism of action. Amphetamine and 2C-I could be considered to have a very similar base structure, yet therer would be no cross tolerance. Any psychedelic that binds and agaonises the 5HT2a and other 5ht receptors will create cross tolerance issues. Structure of a molecule is realtively meaningless.....But yeah, you were right in saying that LSA and LSD will have cross-tolerance; due to MOA not structure though.

:) <3
 
psychs on consecutive nights will give tolerance. how much is case dependent. a high dose the 1st night will give more tolerance. a person with an already high tolerance will have more tolerance. the more similar the substances the more tolerance.

thats what i believe
 
Yes there will be tolerance. All psychedelics will cross tolerate each other.
 
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