Opioids Why does codeine so consistently give me a strong stimulant effect?

[bluejeans]

I'll get a bit of tiredness after 6 hours of a 60mg dosage - but after that, I can stay awake another 20. Nobody has been able to explain why this happens, even my doctor. Daily meds are:

Mirtazipine 30mg
Seroquel 800mg
Valium 10mg
Tramadol 50mg

This didn't happen before I was on seroquel. But rohypnol also caused me to be awake like this.

 

[Pickledlemons]

Does your codeine contain caffeine? It can really add up if you are using recreational dosages. The codeine can overpower the caffeine at first - but its shorter acting - so you can be left with a lot of residual stimulation once the codeine itself wears off.

 

[JohnBoy2000]

I'll get a bit of tiredness after 6 hours of a 60mg dosage - but after that, I can stay awake another 20. Nobody has been able to explain why this happens, even my doctor. Daily meds are:

Mirtazipine 30mg
Seroquel 800mg
Valium 10mg
Tramadol 50mg

This didn't happen before I was on seroquel. But rohypnol also caused me to be awake like this.

I'm always curious to put subjective effects of downstreams effectors relative to upstream cognitive states - and what you describe is so counter intuitive it's actually farcical.

Serious question but, to get some perspective on your cognitive state/disposition, could you post a recent'ish picture of yourself?

 

[Joey]

I find opiates in general almost always gave me energy. I rarely nodded as a heroin addict and have only gotten to any real down point on fentanyl. A good opiate rush was always invigorating to me. Not the same way a stim is, but all the same.

I used to fucking love heroin.

 

[Spideronthewall]

Serious question but, to get some perspective on your cognitive state/disposition, could you post a recent'ish picture of yourself?

This is a ridiculous request to ask...

 

[Fiori di Bella]

With the exception of MS Contin, (morphine sulfate), which I discontinued due to the serious nod it caused, I have found all opiates to provide me with an energy boost. I tend to believe this is related to the euphoria (dopamine, I think?) but I know zero about all the chemistry of these things and can only tell you what I know from my own experience.