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  • BDD Moderators: Keif’ Richards | negrogesic

Why does a crushed 20mg Adderall XR not feel like 20mg Adderall IR

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Addyman

Addyman

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Jan 3, 2011
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California, USA
I crush it completely
I feel like I just wasted it

The XR orally taken lasts 12 hours for me (due to dropping my tolerance)

The XR crushed... Was almost like a placebo

Any insight on why a crushed XR doesn't mimic an IR tablet's effects?
 
I don't know much about adderall, but it could be for a couple of reasons. 1 if the pill is mixed with a waxy substance through out then even crushed the contents of the pill itself may still have the time release coating on the ground up peices, the other reason I can think of is where and how the medication is absorbed into the blood stream effectively, which is why some pills are made to be extended release, so what happens is you take the pill and as it travels down the digestive tract it may be that this drug needs to be absorbed in the intestines rather then the stomach. Crushing the pill may allow the stomach to digest it to soon an there by removing all of the active ingrediants prior to it moving into the lower ends of your digestive tract. As someone once put it pills, capsuls and the like are made to allow the medication to end up into the digestive tract where they are to be fully disolved to get the best effect. With the strong acids in the stomach you could very easily be metabolizing the drug before it gets to where it needs to be to absorb properly for its best effect. So either of those reason could be why your not bypassing the XR, the fact is you may be completely metabolizing all of the drug before it ever hits your blood stream. I dont know the facts of this drug particularly, but those are the common reasons you dont crush or chew XR meds and expect to get an IR reaction. I would try googling it and see if you can find out how an where the drug is metabolized, it may simply be that the acids in the stomach are too much for that drug crushed and its all gone by the time it moves further down in your system. Hope that helps some.
 
I have grinded the beads into fine powder, i feel that when i do this and swallow it, the effects hit me within 10mins much more intense and euphoric than IR tabs, but it seems to not last as long as regular IR addys
 
Not sure why. From my understanding breaking the beads makes it an IR adderall. Did you lose any of the final XR powder?
 
olab7 said:
Not sure why. From my understanding breaking the beads makes it an IR adderall. Did you lose any of the final XR powder?
Click to expand...

No, but it might have to do with intranasal route of administration

I never seemed to like the intranasal route much
 
^^ that sounds more closely to whats happening. The original post did not mention anything about insufflation. When dealing with XR, meds especially ones where the binder is a waxy substance, the binders tend to make the drug non water soluble and the binders would just plug your nose an sinus cavities thus making the bio-availability of the drug extremely low. But again not having any personal experience with adderall, I am not sure if the XR is just in the coating or if it's mixed all throught the pill which would be the waxy substance I'm referring too that is used by some drugs in the binder to making it XR. But either way usually grinding up most XR drugs and swallowing them will bybass the XR to some extent allowing it to hit you more like an IR. I havent heard many people having luck in insufflating drugs unless it's just in the coating and you scrap off the coating and the drug must be water soluble, otherwise it's pretty much a waste.
 
It might have something to do with the binder used that is slowly digested in a time release fashion as opposed to the IR.
 
blackskirt said:
It might have something to do with the binder used that is slowly digested in a time release fashion as opposed to the IR.
Click to expand...

That was my original thought until he mentioned that he was snorting it and not parachuting or swallowing the crushed pills.
 
painenduser said:
That was my original thought until he mentioned that he was snorting it and not parachuting or swallowing the crushed pills.
Click to expand...
I've heard time and time again that adderall contains four amphetamine salts, and some of them actually need to go through the digestive system in order for their effects to be applied. I'm not sure if the XR binder is adequately digested when applied intranasally.
 
Also based on the make up of the pills according to RXlist.com
Rxlist.com said:
ADDERALL XR (amphetamine, dextroamphetamine mixed salts) capsule contains two types of drug-containing beads designed to give a double-pulsed delivery of amphetamines, which prolongs the release of amphetamine
Click to expand...

Basically Adderall XR is made up of these little beads made up of the drug, gelatin, an a polymer. This is what makes Adderall slow release as the body breaks these down slowly. This also makes the drug virtually useless when trying to snort it. The only way to break this down to bypass the XR is to crush them down to an extremely fine powder, or crush them down and try to dissolve them with warm water. Either way you would have to swallow them. They will be ineffective snorted and unless finely ground enough to break up these beads or trying to get them to dissolve in warm water, you will not break the XR. I just did some google searching on this and those are about your only options. Not quite sure there is any more advise that can be given here. Good luck. Why not just try to get IR instead of trying to go through all this work which may or may not work with the XR's? Just a thought :)
 
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blackskirt said:
I've heard time and time again that adderall contains four amphetamine salts, and some of them actually need to go through the digestive system in order for their effects to be applied. I'm not sure if the XR binder is adequately digested when applied intranasally.
Click to expand...

You are correct, I mean you could get a little bit from drip, but nothing worth anything really, again I will quote rxlist.com to back up what we are saying.

rxlist.com said:
ADDERALL XR (amphetamine, dextroamphetamine mixed salts) is a once daily extended-release, single-entity amphetamine product. ADDERALL XR (amphetamine, dextroamphetamine mixed salts) combines the neutral sulfate salts of dextroamphetamine and amphetamine, with the dextro isomer of amphetamine saccharate and d,l-amphetamine aspartate monohydrate
Click to expand...

With out ingestion into the digestive system this drug is useless. So we are pretty much beating a dead horse so to speak. NOTE: No horses were harmed in the writing of this post!
 
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My nose is such a waste </3

I have a perfect druggie nose (super snorter)

and yet adderall xr just doesn't like to be snorted
 
adderall XR is my favorite. the 15mg blue and white generic capsules with beads do the trick. I would crush those bitches up, it would hit hard, then after staying up and coming down I'm hit with a wave above one and a half times the first. I think generic XR is the key. I'm guessing they have less combos of salts, so it's pretty much a 2 stage deal, instead of the other extreme of XR, vyvance, which I never get high off of and reminds me almost nothing of an amphetamine high. Vyvance makes me feel medicated to do something, it's weird and usually uncomfortable. While I'm on the topic of vyvance, please don't abuse it. Amphetamine psychosis is so much worse when it's drawn out for 5 times longer than normal and less than half the high.
 
Addyman said:
I crush it completely
I feel like I just wasted it

The XR orally taken lasts 12 hours for me (due to dropping my tolerance)

The XR crushed... Was almost like a placebo

Any insight on why a crushed XR doesn't mimic an IR tablet's effects?
Click to expand...
in the XR amph pharms, the amphetamine is inside the plastic right, well basically you probably just crushed it up and everything but some still remained in the plastic.
next tiem take a razorblade and chop it to as fine a powder as possible, then drop it in water and drink the water, most of the shit in pharm amps isn't water soluble so the amp would dissolve but most of the other stuff wont.
 
Everyone i ever talked to in person who had used XR and IR adderall said that the XR was less recreational, and had worse sideffects. That was my experience as well. It felt weaker, in terms of ddesirable stimulation, and stronger, in terms of undesirable physical effects.

It makes zero sense, but many people seem to have similar experience with it. IMO, just get the IR's. If you've got a legit perscription, try to get it changed to the instant (maybe justify it by saying it's keeping you up, because it lasts so long? I dunno. I had no trouble getting the IR)
 
TheAzo said:
Everyone i ever talked to in person who had used XR and IR adderall said that the XR was less recreational, and had worse sideffects. That was my experience as well. It felt weaker, in terms of ddesirable stimulation, and stronger, in terms of undesirable physical effects.

It makes zero sense, but many people seem to have similar experience with it. IMO, just get the IR's. If you've got a legit perscription, try to get it changed to the instant (maybe justify it by saying it's keeping you up, because it lasts so long? I dunno. I had no trouble getting the IR)
Click to expand...

I think I'll ATTEMPT to switch from a 20mg XR to 3 15 IRs by saying the isnt strong enough AND doesnt last long enough
 
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